This mixed-methods systematic review synthesized 21 studies of chemotherapy-treated cancer patients with cancer-related cognitive impairment. Memory, concentration, and executive-function problems affected daily life, work, relationships, and emotions. Coping included memory aids, self-regulation, task modification, lifestyle changes, and social support. Perceived benefit is not trial-proven clinical efficacy.
Key findings
- Memory, concentration, and executive-function problems affected daily activities, work, relationships, and emotions.
- Patients sought information, supportive care, and peer support.
- Perceived benefits of memory tools, task adjustment, lifestyle changes, and social support varied; simply powering through was reported as ineffective.
Why this matters globally
The synthesis frames cognitive impairment as a lived-function problem and can inform screening, education, referral, and individualized support. It does not establish any coping strategy as standard treatment because perceived benefit is not controlled-trial efficacy.
Thai researcher contribution
All four authors were affiliated with the Faculty of Nursing, Khon Kaen University, with Jing Li also affiliated with Jinzhou Medical University. The international and Chinese database strategy reflects cross-country nursing collaboration led from Thailand.
Limitations to consider
Heterogeneous populations, measures, cancers, and treatments limit comparison. The synthesis depends on primary-study quality, many strategies were not tested experimentally, search and language limits may omit evidence, and cultural representation was restricted.