Information from the abstract
Objective: To assess maternal and cord blood SARS-CoV-2 anti-receptor binding domain (RBD) immunoglobulin G (IgG) levels in Thai pregnant women following different COVID-19 vaccine regimens, and identify factors influencing these levels. Material and Methods: A cross-sectional study was conducted at a quaternary care hospital in Thailand between April 2022 and February 2023 to evaluate anti-RBD IgG levels at delivery among singleton pregnant women. Participants received either two doses of COVID-19 vaccines, ChAdOx1, BNT162b2, or mRNA-1273 in any combination, or three doses, with one of these vaccines administered as the final dose. Spearman’s correlation was used to assess the relationship between the maternal and cord blood antibody levels. Non-linear least squares regression estimated the effect of time since the last vaccination, while multivariable models identified factors influencing antibody concentrations. Significance was set at p-value
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Related topics: SARS-CoV-2 and COVID-19 Research · COVID-19 Impact on Reproduction · Vaccine Coverage and Hesitancy
Thai researcher and institutional participation
Thitima Suntharasaj · Natthicha Chainarong · Smonrapat Surasombatpattana · Nutsiwat Didas · Alan Frederick Geater · Nannapas Kaewmanee · Rapphon Sawaddisan · Prince of Songkla University
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