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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
Rational Prescribing and Medication Safety74IMPACT SIGNAL
Evidence of global relevance

Assessment of Inappropriate Omeprazole Prescribing, Associated Factors and Financial Impact in the Outpatient Department of a General Hospital in Thailand

A review of 347 outpatient prescriptions for 229 patients from January-June 2025 at one Thai general hospital classified 58.2% of omeprazole prescriptions as potentially inappropriate. Of these, 75.2% lacked an appropriate indication, followed by inappropriate duration.

Thai researchersSaranporn Srithonrat · Chayanat Pongsathabordee · Satawat Kulworahathai · Chidawan Prapat · Aticha Jamratkittiwan · Nichakan Jitakson · Taniya Paiboonvong
Endocrine Emergency Medicine74IMPACT SIGNAL
Evidence of global relevance

Prognostic factors and prognostic risk score of 30-day all-cause mortality in thyroid storm

A retrospective cohort of 115 thyroid-storm patients at a Thai tertiary center had 13% 30-day mortality. An eight-point score using male sex, hypertension, SOFA at least 2, and GCS at most 10 achieved apparent AUC 0.81 and bootstrap-corrected AUC 0.79.

Thai researchersPakpoom Chantrapitak · Worapaka Manosroi · Sittikul Thipbumrung · Pichitchai Atthakomol
Companion-Animal AMR and One Health74IMPACT SIGNAL
Evidence of global relevance

Genomic Characterization, Antimicrobial Resistance Profiles, and tetA Nucleotide Substitutions of Escherichia coli Isolated from Healthy Dogs in Thailand

Fecal samples from 200 healthy dogs at 50 clinics in Chiang Mai and Nakhon Si Thammarat during January-March 2026 yielded 66 E. coli isolates. Resistance reached 100% for ampicillin, 84.85% for piperacillin, 60.61% for ceftriaxone, 56.06% for tetracycline, and 47% multidrug resistance.

Thai researchersRavisa Warin · Naparat Suttidate · Wanna Suriyasathaporn · Witaya Suriyasathaporn · Ratchadaporn Boripun
Microalgae and Energy Harvesting74IMPACT SIGNAL
Evidence of global relevance

Immobilized microalgae-driven triboelectric nanogenerators for sustainable bioelectricity production

Thai researchers immobilized living Chlorella vulgaris TISTR 8580 at different densities on aluminum electrodes as a triboelectric layer for solid-solid and solid-liquid interactions, reporting peak output of 110 V and 330 nA.

Thai researchersChalampol Janpum · Tanakit Komkhum · Naratip Vittayakorn · Kamon Thinsurat · Chawalit Ngamcharussrivichai · Pichaya In-na
Alternative Proteins, Drying, and Flavor73IMPACT SIGNAL
Evidence of global relevance

Drying-Induced Structural and Oxidative Transformations in Sustainable Proteins: Impact on Physicochemical Properties and Flavor-Binding Functionality

This review proposes a structure-process-function framework explaining how hot-air, heat-pump, microwave, and freeze-drying differently unfold, aggregate, and oxidize plant and marine proteins, changing how volatile flavors are bound, retained, and released.

Thai researchersYoon Hlaine Barani · Passakorn Kingwascharapong · Saroat Rawdkuen
Ultrasound Nanomaterials and Cancer Immunity73IMPACT SIGNAL
Evidence of global relevance

Ultrasound-Activated Metal–Organic Frameworks Incorporated Polyacrylonitrile Nanofibers Promote Macrophage Inflammation

Researchers embedded a manganese-titanium metal-organic framework in polyacrylonitrile nanofibers to convert ultrasound into electrical stimulation. The composite generated a peak 0.24 V and, under ultrasound in RAW-Blue cells, activated NF-kB, TNF-alpha, IL-6, and transient calcium influx.

Thai researchersMitsuhiro Ebara
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
74IMPACT SIGNAL
Clinical Medicine

Ambient PM2.5 and respiratory tract disorder–related outpatient visits among healthcare workers: an ecological time-series study

BMC Public Health

Thailand-affiliated authors
Chaturon Tangsangwornthamma · Sivakorn Suntinipanon · Chathaya Wongrathanandha · Natnaree Aimyong
Institutions
Ramathibodi Hospital · Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Clinical Prognostic Factors and Survival Risk Stratification for Advanced Biliary Tract Cancer Treated with Gemcitabine-Based Palliative Chemotherapy: A Real-World Retrospective Study

Life

Thailand-affiliated authors
Jirapat Wonglhow · Arunee Dechaphunkul · Patrapim Sunpaweravong · Chirawadee Sathitruangsak · Panu Wetwittayakhlang
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

A Proteomic Study Reveals the Relationship Between Arterial Stiffness and Hyperglycemia in Middle-Aged Obese Men

Clinical Diabetology

Thailand-affiliated authors
Thanutchaporn Nutmakul · Nontawit Auppawat · Sittiruk Roytrakul · Jintana Sirivarasai · Sirasa Ruangritchankul · Wutarak Monsuwan
Institutions
Ramathibodi Hospital · National Science and Technology Development Agency
74IMPACT SIGNAL
Clinical Medicine

Skipjack tuna bone-derived biocalcium ameliorates osteoblast and osteoclast differentiation through microRNA21 regulation

iScience

Thailand-affiliated authors
Sompot Jantarawong · Sudarat Phuntong · Saowapak Kanobthammakul · Papitchaya Watcharanurak · Jidapa Szekely · Jedsada Kaewrakmuk · Eakolarn Chotianuson · Doungporn Amornlerdpison · Chutima S. Vaddhanaphuti · Theeraphol Senphan · Yutthana Pengjam
Institutions
Prince of Songkla University · Suan Sunandha Rajabhat University · Maejo University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Effects of Fine Particulate Matter on Systemic Inflammatory Biomarkers in Elderly Patients with Chronic Obstructive Pulmonary Disease Versus the Healthy Elderly: A Pilot Study

International Journal of Molecular Sciences

Thailand-affiliated authors
Warawut Chaiwong · Chalerm Liwsrisakun · Pilaiporn Duangjit · Juthamas Inchai · Chaiwat Bumroongkit · Athavudh Deesomchok · Theerakorn Theerakittikul · Atikun Limsukon · Pattraporn Tajarernmuang · Nutchanok Niyatiwatchanchai · Konlawij Trongtrakul · Chittrawadee Chitchun · Nipon Chattipakorn · Siriporn C. Chattipakorn · Nattayaporn Apaijai · Chaicharn Pothirat
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Abalone-derived dermatopontin and its RFK-containing peptide promote osteogenesis via TGF-β/Smad signaling pathway

International Journal of Biological Macromolecules

Thailand-affiliated authors
Purimpuch Soongnart · Supawich Boonkua · Orawan Thongsum · Rueangtip Chantunmapitak · Primwadee Wichienwat · Pan Soonsawad · Wattana Weerachatyanukul · Aungkura Supokawej · Somluk Asuvapongpatana
Institutions
Mahidol University · Thammasat University · Mahamakut Buddhist University
74IMPACT SIGNAL
Multidisciplinary

Nanoclay, calcium alginate, and composite soil amendments mitigate drought effects on wheat growth and water-use efficiency

Frontiers in Plant Science

Thailand-affiliated authors
Khalifa M. Alteneiji · Razan F. Alhammadi · Lamya Alsuwaidi · Walid Abo Baker · Mohammad A. Al-Faqieh
Institutions
Department of Livestock Development
74IMPACT SIGNAL
Clinical Medicine

Organic UV Filter Exposure in Children of Indonesia, Thailand, and Saudi Arabia – Urinary Concentrations, Risks, and Potential Sources

Integrated Environmental Assessment and Management

Thailand-affiliated authors
Kraichat Tantrakarnapa · Wissanupong Kliengchuay
Institutions
Mahidol Oxford Tropical Medicine Research Unit
74IMPACT SIGNAL
Clinical Medicine

Investigation of Oncogenic Gene Mutation and Associated Protein Expression in Ameloblastic Carcinoma

Oral Diseases

Thailand-affiliated authors
Puangwan Lapthanasupkul · Jintana Pankam · Siribang-on Piboonniyom Khovidhunkit · Prapapun Seneetuntigul · Nakarin Kitkumthorn
Institutions
Mahidol University · Ministry of Public Health · Burapha University
74IMPACT SIGNAL
Clinical Medicine

Late-follicular androgen and estrogen rise associated with clinical pregnancy in IVF/ICSI with granulosa cell studies

Reproduction and Fertility

Thailand-affiliated authors
Rungnapa Sririwichitchai · Chantacha Sitticharoon · Issarawan Keadkraichaiwat · Pailin Maikaew · Suchawadee Chanheng · Somsin Petyim
Institutions
Siriraj Hospital
74IMPACT SIGNAL
Clinical Medicine

Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study

Renal Failure

Thailand-affiliated authors
Ulugbek Ochilov
Institutions
Asia Pacific International University
73IMPACT SIGNAL
Fundamental Science

L-shell X-ray production cross sections for thick silver targets induced by MeV Cuq+ ions with velocities well below the Ag L-shell Bohr velocity

Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms

Thailand-affiliated authors
J. Hussain · L.D. Yu · U. Tippawan
Institutions
Chiang Mai University · Thailand Center of Excellence in Physics
73IMPACT SIGNAL
Multidisciplinary

Effects of Reactive Footwork Training Versus Simple-Reaction Training on Lower-Extremity Motor Coordination, Dynamic Balance, and Cognitive Screening Scores in University Sport Science Students: A Pilot Randomised Controlled Trial

Sports

Thailand-affiliated authors
Arisa Sespheng · Kantapong Kaewmuan · Pitak Chaimiphak · Thanakrit Mekkeaw · Suttinee Petmunee · Saithip Piyatammakun · Thanatchaporn Putthikrittayakarn · Nurfajjaree Loteh · Natkanlaya Nonthanapapol
Institutions
Walailak University
73IMPACT SIGNAL
Multidisciplinary

PHOTOLUMINESCENCE AND SCINTILLATION PROPERTIES OF CE-DOPED Lu0.5Gd0.5AlO3 SINGLE CRYSTALS GROWTH BY FLOATING ZONE METHOD

Suranaree Journal of Science and Technology

Thailand-affiliated authors
Tharittawat Tharasook · Prom Kantuptim
Institutions
Kasetsart University
73IMPACT SIGNAL
Clinical Medicine

Evaluation of pyocin activity and pyocin-related gene distribution in multidrug- and extensively drug-resistant Pseudomonas aeruginosa isolates from Thailand

PeerJ

Thailand-affiliated authors
Phatcharin Laosena · Punthira Suppaiboolkij · Pornpavee Nualnisachol · Jiraphan Premsuriya
Institutions
Chulabhorn Royal Academy · Kasetsart University · Chulabhorn Graduate Institute · Chulabhorn Hospital
73IMPACT SIGNAL
Clinical Medicine

Foot Shape in Women With and Without Hallux Valgus Determined Using 3‐Dimensional Foot Scanning

Journal of Foot and Ankle Research

Thailand-affiliated authors
Hylton B. Menz
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Optimized Self‐Healing and Antioxidant Hydrogels Based on Gallic Acid–Blended Quaternized Chitosan and Oxidized Pectin for Potential Wound Dressing Applications

Journal of Biomedical Materials Research Part A

Thailand-affiliated authors
Porntipa Pankongadisak · Kitipong Kiti · Pimpakan Faijai · Mueanchan Chanmontri · Orawan Suwantong
Institutions
Mae Fah Luang University
73IMPACT SIGNAL
Multidisciplinary

Development of Indomethacin Nanostructure Lipid Carrier Incorporated in Emulgel

Journal of Health Science and Medical Research

Thailand-affiliated authors
Kanokwan Singpanna · Prasopchai Patrojanasophon · Chaiyakarn Pornpitchanarong · Nattanit Aekwattanaphol · Chanwit Changcharoensuk · Peerapat Chidchai
Institutions
Siam University · Silpakorn University · Prince of Songkla University
73IMPACT SIGNAL
Clinical Medicine

Dysregulation of the miR-29c-3p/collagen axis induces spermatogenic failure in heat stress and non-obstructive azoospermia

Asian Journal of Andrology

Thailand-affiliated authors
Shou‐Bo Zhang
Institutions
Police General Hospital
73IMPACT SIGNAL
Clinical Medicine

UHPLC/QTOF-mass spectrometry-based metabolomic analysis of Riceberry during simulated in vitro digestion

Acta Alimentaria

Thailand-affiliated authors
S. Punyauppa-Path · S. Phupaboon · W. Pilap · U. Thonsri · P. Kiatprasert · Patcharee Boonsiri
Institutions
Rajamangala University of Technology Isan, Surin Campus · Mahasarakham University · Thammasat University · Khon Kaen University
73IMPACT SIGNAL
Clinical Medicine

Caregiver Coaching in Occupational Therapy–Led Early Intervention: A Scoping Review

Child Care Health and Development

Thailand-affiliated authors
Krongporn Chinchai · Thapanee Panunpang · Chirathip Thawisuk · Rujira Jaikaew
Institutions
Chiang Mai University
73IMPACT SIGNAL
Engineering

Coupled effects of center-of-gravity position and added mass on vortex-induced vibration and galloping-based hydrokinetic piezoelectric energy harvesting

Applied Physics Letters

Thailand-affiliated authors
Patcharakon Siriyothai · Chartsiri Rujasiri · Chawalit Kittichaikarn
Institutions
Kasetsart University
73IMPACT SIGNAL
Global Public Health

Molecular detection and multilocus genotyping of Toxoplasma gondii in archived stray-cat fecal DNA from central and western Thailand

Veterinary World

Thailand-affiliated authors
Ruenruetai Udonsom · Aongart Mahittikorn · Supaluk Popruk
Institutions
Mahidol University
73IMPACT SIGNAL
Digital Health

Representation learning for low-data protein fitness prediction using sequence–structure embeddings and graph neural networks

Scientific Reports

Thailand-affiliated authors
Chanoknun Phunnasorn · Narupat Hongdilokkul · Wasakorn Laesanklang · Charin Modchang · Tipaluck Krityakierne
Institutions
Mahidol University · Centre of Excellence in Mathematics · Ministry of Higher Education, Science, Research and Innovation
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link