People with BRCA-associated cancer risk or Lynch syndrome may face malignancy at ages that overlap with family-building. The article frames five connected tasks: cancer prevention, fertility consequences of risk-reducing strategies, fertili…
Journal
International Journal of Gynecology & Obstetrics
Thai researchers
Sarikapan Wilailak
Thai institutions
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Purpose Despite the widespread international use of the Principal Instructional Management Rating Scale (PIMRS), limited contemporary attention has focused on its adaptation across cultural contexts and the breadth of validation evidence su…
Pythium insidiosum is an important oomycete pathogen that causes pythiosis, a severe infectious disease affecting humans and animals worldwide. Understanding its genetic diversity is essential for accurate species identification, genotyping…
Abstract Introduction Autistic traits (ATs) are linked to increased vulnerability to psychopathology. While sex differences are studied in clinical autism, little is known about these associations in the general population. This study exami…
Journal
European Archives of Psychiatry and Clinical Neuroscience
This open letter synthesizes the 2024 Wellcome Major International Programmes meeting, which brought together research-institution representatives from Africa, Asia, and the United Kingdom. Participants identified limited clinical-trial lit…
Journal
Wellcome Open Research
Thai researchers
Nicholas P J Day · Nicholas J White
Thai institutions
Mahidol University through the Mahidol Oxford Tropical Medicine Research Unit (MORU)
An all-Thai team analyzed co-authorship structures in five leading Q1 health-professions-education journals from 2015 through 2024, covering 13,187 publications, 45,366 authors, and affiliations in 162 countries. Annual output grew 2.7-fold…
An interim prospective secondary analysis from a parent trial at one university hospital followed 170 frail older adults after medical-ward discharge. A broad composite of emergency visits, unplanned outpatient visits, and readmissions rose…
Since the 2021 military coup, displacement from Myanmar into Thailand has accelerated dramatically. Although many meet international criteria for refugeehood, those fleeing Myanmar are largely reconstituted as documented and undocumented mi…
Background Zoonotic malaria caused by Plasmodium knowlesi poses a growing threat to malaria elimination. In Thailand, Ranong Province reports the highest incidence nationally, yet the role of long-tailed macaques ( Macaca fascicularis ) as …
Journal
Wellcome Open Research
Thai researchers
Pyae Linn Aung · Sirasate Bantuchai · Jetsumon Sattabongkot
Abstract Background Robot-assisted kidney transplantation (RAKT) has emerged as a minimally invasive alternative to conventional open kidney transplantation. Evidence regarding the feasibility of establishing RAKT programs in RAKT-naïve tra…
Plasmodium vivax is a major malaria parasite that causes acute illness in millions of people each year. Transmission-blocking vaccines (TBVs) could contribute substantially to malaria elimination, although none has yet been approved. We pre…
Abstract Osteoarthritis (OA) is a progressive joint disease characterized by cartilage destruction and is increasingly recognized as involving chronic low-grade inflammation. Synovitis contributes to OA progression through the production of…
The rising incidence of lung cancer is increasingly linked to fine particulate matter (PM2.5) exposure, highlighting its role as a risk factor of lung carcinogenesis. However, the molecular mechanisms behind PM2.5 and the disease remain inc…
BACKGROUND Continued use of personal continuous glucose monitoring (CGM) devices is recommended for people with diabetes receiving insulin therapy during hospitalization to achieve better glycemic control and reduce hypoglycemia.However, da…
Abstract Southeast Asia is widely recognized as a global biodiversity hotspot with a complex geological history and high species richness across multiple taxa. The pill millipede genus Rhopalomeris Verhoeff, 1906 has received increasing tax…
Researchers from the universities of Phayao, Mahidol, and Walailak tested polished and unpolished Yoom Noon rice extracts in HCT116 and HT29 colorectal cancer cells. They observed reduced viability, apoptosis, cell-cycle arrest, and lower m…
In Thailand, physicians and pharmacists have distinct professional roles; however, their responsibilities are closely interconnected. Effective communication between these professionals is crucial, as conflicts in their communication can ad…
Purpose Amid growing sustainability concerns and the increasing ubiquity of e-commerce and digital lifestyles, sustainable gamification has emerged as a vital strategy for promoting pro-environmental behavioral intention. This study aims to…
Purpose This study aims to examine how the 2025 Thai–Cambodian border conflict disrupted education in four northeastern Thai provinces, documents governance failures that produced compounded harm for cross-border Cambodian and Khmer-speakin…
Recurrent urinary tract infections (rUTIs)—increasingly due to multidrug-resistant organisms—affect up to half of kidney transplant recipients (KTRs) in the first year and are associated with eGFR decline, rejection, and reduced graft survi…
At least 264 Recovery Colleges have been identified in 31 countries, yet the RECOLLECT tools used to define and assess the model originated in a high-income Anglophone context. A two-round Delphi used cross-cultural de-centring: 54 panellis…
Journal
npj Mental Health Research
Thai researchers
Peanchanan Leah
Thai institutions
Ratchasuda Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University
A Mahidol University team translated the Self-Compassion Scale through two forward translations, synthesis, two back-translations, review by the translators plus three additional experts, and a 20-person focus group before analysing 428 Tha…
Journal
Journal of Health Science and Medical Research
Thai researchers
Chavisara Jombunud Na Ayudhaya · Komsan Kiatrungrit · Wanlop Atsariyasing
Thai institutions
Faculty of Graduate Studies, Mahidol University · Department of Psychiatry, Faculty of Medicine Ramathibodi Hospital, Mahidol University · Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University
Type 2 diabetes (T2D) with established atherosclerotic cardiovascular disease (ASCVD) imposes a substantial clinical and economic burden in Thailand. Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 re…
Metabolic reprogramming and lipid remodeling are increasingly recognized as key processes underlying carcinogenesis and cancer treatment failure. The liver, as a central hub for lipid metabolism and homeostasis, is particularly susceptible …
Salmonella contamination in poultry meat remains a major global food safety concern, necessitating rapid and reliable viability-targeted detection methods. Here, we developed a platform of phage amplification (PA)-assisted lateral flow bios…
Abstract Mass spectrometry imaging (MSI) is an advancing platform that enables the spatial mapping of molecular features directly onto tissue sections. The chemical profile is scanned pixel by pixel: analytes are ionized at each position an…
Chronic liver disease affects over a billion people worldwide. Despite diverse etiologies, a unifying feature of chronic liver disease is the liver's impaired ability to regenerate during progression to cirrhosis, but no common molecular me…
O.A. is investigator, consultant, and/or speaker for Leo Pharma, AbbVie, Sanofi-Genzyme, L'Oréal/La Roche Posay, Novartis, Incyte, Amgen, Janssen-Cilag, and Bioderma/NAOS. The other authors have no conflicts to declare. The data that suppor…
Midbrain dopamine (DA)-neurons are slow pacemakers that continuously fire action potentials, maintaining basal extracellular DA levels in target regions. The sodium leak channel NALCN has been identified as a key contributor in the pacemake…
A persistent care gap leaves many patients without anti-osteoporosis medications (AOMs) after hip fracture, despite their proven benefit in preventing secondary fractures. We investigated the factors associated with orthopedic surgeons’ int…
Specific learning disorder (SLD) is a neurodevelopmental disorder characterized by difficulties in reading, writing, and mathematics despite normal intelligence. One of the most common comorbidity of SLD is attention-deficit hyperactivity d…
MXenes belong to a structurally diverse family of two-dimensional transition metal carbides, nitrides, and carbonitrides defined by the general formula M n +1 X n T x . Over the last decade they emerged as a functionally rich class of nanom…
Personalized neoantigen vaccines promise precise cancer immunotherapy, yet identifying immunogenic epitopes remains challenging. This review evaluates bioinformatics and multi-omics pipelines across a four-tier framework: variant-to-candida…
Sotagliflozin (SOTA), a dual sodium–glucose cotransporter 1 and 2 (SGLT1/2) inhibitor, reduces adverse cardiovascular outcomes in patients with heart failure; however, its cardioprotective mechanisms in volume overload–induced heart failure…
Lymphedema causes progressive remodeling of subcutaneous adipose tissue, but noninvasive assessment of early adipocyte changes remains limited. This cross-sectional study investigated whether subcutaneous tissue ultrasonography, assessed us…
Abstract The Chikungunya virus (CHIKV) infection induces an acute illness and ongoing inflammatory symptoms, with macrophages believed to play significant yet not fully understood roles. To characterize host cellular responses associated wi…
Lyssaviruses cause rabies in mammals, a viral encephalomyelitis that is almost always fatal once clinical symptoms develop and can be transmitted to humans. Given this high fatality rate, strict biosafety measures are essential during labor…
Abstract* Background Thailand is navigating one of the most rapid demographic transitions in human history, shifting from an aging profile into a deeply consolidated aged national structure. Within this profound demographic compression, the…
Background Older adults represent a rapidly growing segment of the hemodialysis (HD) patient population. However, the specific clinical variations and dialysis management strategies employed for geriatric patients in Thailand remain poorly …
This study developed and characterized a pectin (PEC) based coating incorporated with green tea spent extract (GTSE) and/or nisin. Further, Pacific white shrimp were treated with the developed coating and investigated for physicochemical, t…
This single-school mixed-methods study examined records for 1,021 Thai medical students admitted in 2017–2022 through the portfolio-based TCAS1 or examination-based TCAS3 route. Documented extracurricular research participation was 21.1% ve…
Faculty of Medicine Ramathibodi Hospital, Mahidol University · Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University
ABSTRACT Simulation‐based learning is widely adopted in engineering education because it enables learners to explore complex engineering systems through interactive and self‐paced learning. However, developing educational simulations tradit…
Light is a key abiotic factor regulating plant-environment interactions; its short-term effects on terpenoid biosynthesis in Artemisia annua remain unclear under controlled environments. This study investigated how short-term variations in …
A secondary analysis of 1,666 migrant and displaced Myanmar mothers on the Thailand–Myanmar border found that first birth at ages 12–19 or 20–24 was associated with more frequent self-reported physical maltreatment than first birth at age 2…
Abstract Background Labor shortages in Thailand's industrial sector have intensified workloads for existing employees, potentially impacting the mental health of workers, particularly those residing in dormitories with limited social suppor…
Background The Balance Evaluation Systems Test (BESTest) and its stroke-specific short version (S-BESTest) are widely used to evaluate balance after stroke. However, clinically meaningful classifications of balance ability derived from thes…
Abstract Background: To date, standard treatment for locally advanced rectal cancer (LARC) is total neoadjuvant therapy (TNT). Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is the other option. This study aimed to compare the out…
Polyhedral oligomeric silsesquioxanes (POSS) and related silsesquioxanes provide an atomically precise platform for organic–inorganic hybrid electronics. Existing reviews mainly address synthesis, functionalisation, and application breadth;…
Background: Massive pulmonary embolism (PE) remains a leading cause of preventable perioperative mortality after bariatric surgery. Cardiopulmonary resuscitation (CPR) is challenging in patients with extreme obesity, and extracorporeal card…
Thirty in-depth interviews in Siem Pang district, northeastern Cambodia, showed that over-the-counter antibiotic use reflects cost, distance, convenience, urgent household needs, and dispensers' economic pressures as well as limited knowled…
A randomized crossover trial with 30 fourth-year preclinical dental students compared verbal, visual, haptic, and no VR mirror guidance during simulated maxillary-molar access preparation. Each guidance mode reduced the outcome error score …
Journal
JMIR Serious Games
Thai researchers
Unthitar Suranin · Siriwan Suebnukarn · Peter Haddawy · Myat Su Yin · Panuroot Aguilar
A pilot randomised within-subject trial in 14 unilateral transfemoral prosthesis users compared a low-profile, femoral-adducted Asian Transfemoral Socket with each participant's usual socket after six weeks of ATS use. Twelve participants a…
Sirindhorn School of Prosthetics and Orthotics, Faculty of Medicine Siriraj Hospital, Mahidol University · Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University
A randomised controlled trial assigned 44 older lower-limb prosthesis users to usual care or education plus 16 home exercises three times weekly for eight weeks; 41 completed follow-up. Change in Timed Up and Go did not differ between group…
This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured …
Journal
The Lancet Regional Health – Southeast Asia
Thai researchers
Suthat Fucharoen · Kittiphong Paiboonsukwong
Thai institutions
Mahidol University · Samitivej Srinakarin Hospital
Thalassaemia Epidemiology and Public Health Systems
This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and pro…
Journal
The Lancet Regional Health – Southeast Asia
Thai researchers
Suthat Fucharoen · Kittiphong Paiboonsukwong
Thai institutions
Mahidol University · Samitivej Srinakarin Hospital
Background Traditional case-based learning lacks opportunities for students to deeply engage within their own disciplines before cross-field collaboration. The Preclinical Multidisciplinary Case-Based Learning (PM-CBL) approach was develope…
Peer-to-peer (P2P) energy trading in industrial settings is rarely validated with metered data. This paper studies the E-Infinity Ecosystem, coupling the X-Changer trading platform with Energinx IoT smart meters that limit reverse power flo…
National Medicines Policies (NMPs) aim to ensure equitable access, quality and rational use of medicines. However, systematic evidence on whether the actions set out in such policies are actually operating remains limited. In Nepal, the 199…
While coaching is widely acknowledged as vital for positive youth development, empirical evidence remains limited regarding how multidimensional coaching behaviors uniquely predict distinct life skill domains among university student-athlet…
Journal
Sportis Scientific Journal of School Sport Physical Education and Psychomotricity
BACKGROUND AND AIM: Helicobacter pylori infection remains a major cause of gastric cancer, peptic ulcer disease, and dyspepsia-related morbidity across ASEAN. Since the first Bangkok Consensus Report in 2018, major advances have emerged in …
