Spore-forming Bacillus probiotics are widely used in aquaculture, but host-associated strains from Siamese fighting fish (Betta splendens Regan) remain uncharacterized. Ten Bacillus isolates were recovered from the gastrointestinal tract of…
Triple-negative breast cancer (TNBC) is an aggressive and molecularly heterogeneous breast cancer subtype. We developed a six-gene oxidative stress-related signature (BAG5, ANXA2, LONP1, GBE1, CBR1, and DDIT4) in GSE58812 (107 patients; 29 …
Background Patients with chronic kidney disease (CKD) may be vulnerable to thiamine insufficiency due to dietary restrictions, altered metabolism, and renal replacement therapy. We aimed to determine the prevalence of functional thiamine de…
High discriminative performance alone does not ensure reliable clinical decision support; well-calibrated confidence estimates are also essential. Standard deterministic deep learning classifiers produce probability predictions without expl…
Renal tumors are the second most common type of urological cancer.These tumors consist of renal cell carcinoma (RCC; 80-85%) and upper tract urothelial carcinoma (UTUC; 5-10%).Accurate preoperative differentiation between these two entities…
Neurodegenerative diseases are closely associated with chronic neuroinflammation and oxidative stress. Centella asiatica (L.) Urb. is a medicinal plant with recognized cognitive-enhancing and neuroprotective properties. This study optimized…
Introduction and aims Accurate radiographic assessment of retained roots (RR) and periodontally compromised teeth (PCT) are critical for dental diagnosis. This study aimed to develop and evaluate deep learning models for the automated detec…
ABSTRACT Background and Aim Incomplete resection after cold snare polypectomy (CSP) remains a concern. CSP may sometimes require a forcible pull (“forced CSP”), which increases the incomplete resection rate (IRR). Submucosal injection befor…
Background Malaysia is a predominantly Muslim, upper-middle-income country where approximately 10% of the population consumes alcohol, yet heavy episodic drinking is common among drinkers. Despite multiple excise duty reforms between 2000 a…
Pythium insidiosum is an important oomycete pathogen that causes pythiosis, a severe infectious disease affecting humans and animals worldwide. Understanding its genetic diversity is essential for accurate species identification, genotyping…
Abstract Objectives This study evaluated the effectiveness of an integrated, application‐supported mindfulness‐based cognitive therapy (MBCT) programme in reducing depressive symptoms among adolescents with non‐suicidal self‐injury (NSSI). …
Abstract Introduction Autistic traits (ATs) are linked to increased vulnerability to psychopathology. While sex differences are studied in clinical autism, little is known about these associations in the general population. This study exami…
Journal
European Archives of Psychiatry and Clinical Neuroscience
Background and Aim: Plasmodium falciparum malaria remains a major cause of severe disease and mortality, with acute kidney injury (AKI) representing an important complication associated with poor clinical outcomes. Although conventional blo…
INTRODUCTION: Adrenal infections are an underrecognized but clinically significant cause of primary adrenal insufficiency (PAI). OBJECTIVES: This review proposes a diagnostic algorithm for the evaluation of suspected cases. RESULTS: The mos…
ABSTRACT Background Benign paroxysmal positional vertigo (BPPV) is a common cause of vertigo encountered in general practice. The definitive diagnosis relies on the Dix‐Hallpike test (DHT), which remains underperformed in primary care due t…
Journal
Journal of General and Family Medicine
Thai researchers
Suwicha Kaewsiri Isaradisaikul · Pitchayanan Namung · Sanathorn Chowsilpa
This open letter synthesizes the 2024 Wellcome Major International Programmes meeting, which brought together research-institution representatives from Africa, Asia, and the United Kingdom. Participants identified limited clinical-trial lit…
Journal
Wellcome Open Research
Thai researchers
Nicholas P J Day · Nicholas J White
Thai institutions
Mahidol University through the Mahidol Oxford Tropical Medicine Research Unit (MORU)
Ascomycete diversity in Yunnan Province, China, remains substantially underexplored. Many species likely remain undetected. This study aimed to discover the ascomycete diversity in Yunnan, China, depending on three fungal collections obtain…
Background Zoonotic malaria caused by Plasmodium knowlesi poses a growing threat to malaria elimination. In Thailand, Ranong Province reports the highest incidence nationally, yet the role of long-tailed macaques ( Macaca fascicularis ) as …
Journal
Wellcome Open Research
Thai researchers
Pyae Linn Aung · Sirasate Bantuchai · Jetsumon Sattabongkot
Ants are a biologically significant group of insects, classified in the family Formicidae. Typically, ants are found in terrestrial ecosystems, including subterranean habitats and within trunks, branches, or subcortical cavities. Ant-fungus…
Journal
Phytotaxa
Thai researchers
GAYANA O. WEERASINGHE · Chitrabhanu Sharma Bhunjun · Chayanard Phukhamsakda · Ashani D. Madagammana · Kevin D. Hyde
Background: Centrifugation-based hematocrit (Hct) testing remains widely used in decentralized primary care settings where access to automated hematology analyzers may be limited. Appropriate proficiency testing (PT) performance assessment …
Abstract Background Robot-assisted kidney transplantation (RAKT) has emerged as a minimally invasive alternative to conventional open kidney transplantation. Evidence regarding the feasibility of establishing RAKT programs in RAKT-naïve tra…
BACKGROUND: Dengue fever remains a major public health concern in tropical regions, particularly in Southeast Asia. Effective prevention depends on the community's understanding of both dengue control measures and vector surveillance system…
Plasmodium vivax is a major malaria parasite that causes acute illness in millions of people each year. Transmission-blocking vaccines (TBVs) could contribute substantially to malaria elimination, although none has yet been approved. We pre…
ABSTRACT The global spread of multidrug-resistant tuberculosis (MDR-TB) remains a major challenge to tuberculosis control programs, particularly in resource-limited settings where access to rapid molecular drug-susceptibility testing is lim…
BACKGROUND: Haemosporidian ("malaria") parasites are a diverse group of vector-borne apicomplexan parasites that infect a wide range of vertebrate hosts, including humans. Bats harbour a remarkable diversity of haemosporidians and are consi…
Chronic erosive dermatopathy (CED) associated with ectoparasites was investigated in Nile tilapia (Oreochromis niloticus). Between 2023 and 2024, craniofacial lesions occurred at a prevalence of
Abstract Osteoarthritis (OA) is a progressive joint disease characterized by cartilage destruction and is increasingly recognized as involving chronic low-grade inflammation. Synovitis contributes to OA progression through the production of…
The rising incidence of lung cancer is increasingly linked to fine particulate matter (PM2.5) exposure, highlighting its role as a risk factor of lung carcinogenesis. However, the molecular mechanisms behind PM2.5 and the disease remain inc…
Objective To compare the caries-arrest effectiveness in primary teeth between 38% Silver Diamine Fluoride (SDF) applied for 10 seconds (s) followed by 20 s of light curing (SDF10LC) and 38% SDF applied for 60 s (SDF60). A secondary objectiv…
Journal
International Dental Journal
Thai researchers
Nuttha Wannapaka · Chutima Trairatvorakul · Marcio A. da Fonseca · Somkamol Vanichvatana · Oranuch Techatharatip
OBJECTIVES: To evaluate the feasibility and short-term outcomes of physician-modified Endurant limbs (PMEGs) for internal iliac artery (IIA) preservation in patients with narrow common iliac artery (CIA) anatomy, with descriptive comparison…
BACKGROUND Continued use of personal continuous glucose monitoring (CGM) devices is recommended for people with diabetes receiving insulin therapy during hospitalization to achieve better glycemic control and reduce hypoglycemia.However, da…
BACKGROUND: Upper trapezius myofascial pain syndrome (MPS) is a common contributor to chronic neck pain and functional limitations. Repetitive peripheral magnetic stimulation (rPMS) has emerged as a non-invasive neuromodulatory intervention…
Background Postoperative nausea vomiting (PONV) is quite common among patients who underwent cesarean section under spinal anesthesia with intrathecal morphine (ITMO). Nalbuphine is a mu receptor antagonist and kappa receptor agonist, which…
It is well established that ectoparasite infection can increase the pathogenicity of, and host susceptibility to, bacterial infections in fish, including rainbow trout; however, no interaction between the ectoparasite Gyrodactylus and the b…
In the present era, modern drug delivery systems play a fundamental role in ensuring the systematic delivery of the drug into the body, reaching the desired targets. Across recent decades, the drug delivery system has evolved from simple or…
OBJECTIVE: To evaluate the diagnostic performance of ultrasonographic median nerve cross-sectional area (CSA-M) for carpal tunnel syndrome (CTS) in wheelchair users with spinal cord injury (SCI), and to identify clinically relevant diagnost…
Journal
American Journal of Physical Medicine & Rehabilitation
Fractional operators are used in biomedical balance laws to encode memory. However, the order of the fractional operator used in these models is not the same as the memory recovered from the patients. This review maps one hundred scientific…
Background: Intensive care unit (ICU)-acquired weakness is a significant complication affecting approximately 34.1% of ICU patients, leading to muscle atrophy, prolonged hospitalization, and increased mortality. Early mobilization (EM) is a…
BACKGROUND AIMS: Management of portal hypertension in children including primary prophylaxis of variceal bleeding is controversial due to limited understanding of mortality risk after first variceal hemorrhage (1VH). This international mult…
Emerging infectious diseases threaten global health security, particularly where integrated human-animal-environment surveillance is limited. In May 2021, Chad reported an influenza-like illness (ILI) outbreak in the Abéché Health District …
Journal
Sahelian Journal of Responsible One Health
Thai researchers
Madina Hadjer · Fatimé Abdelrazack · Mahamat Ali Bolti · Mahamat Fayiz Abakar
Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patte…
Macadamia , a tropical and subtropical plant, is one of the most popular and nutritious nuts worldwide. Previous studies on macadamia-associated fungi have mainly focused on pathogenic and endophytic species, but the diversity and taxonomy …
Cholangiocarcinoma (CCA) exhibits diverse responses to chemotherapy, underscoring the need for drug sensitivity biomarkers. This proof-of-concept study utilized Fourier transform infrared (FTIR) spectral features to identify ex vivo gemcita…
Abstract Topical glaucoma therapy can affect the ocular surface, but objective longitudinal data on conjunctival hyperemia are limited. We prospectively followed 31 patients naive to topical antiglaucoma therapy for 24 weeks after treatment…
Dengue virus remains a major global health threat due to its four antigenically diverse serotypes and limited treatment and vaccine options. This study aimed to design and evaluate a rational tetravalent multi-epitope vaccine capable of eli…
Lymphoma constitutes a substantial and increasing burden of hematologic malignancy in Thailand and globally, while its etiology remains incompletely characterized. Occupational factors have been implicated in lymphomagenesis; however, evide…
Journal
Cancer Prevention Research
Thai researchers
Chatchai Ekpanyaskul · Suleeporn Sangrajung
Thai institutions
Srinakharinwirot University · Ministry of Public Health
Objective To compare the prevalence, experience, and distribution of early childhood caries (ECC) between children with cleft lip and/or palate (CL/P) and children without CL/P and to identify associated risk factors. Setting University cle…
Loose anagen hair syndrome (LAHS) is a rare, non-scarring alopecia that may occur sporadically or follow autosomal dominant inheritance. The objective of this study was to review the etiology, clinical presentation, diagnostic features (inc…
Hemophilia A is a rare genetic disorder caused by deficiency of coagulation factor VIII resulting from pathogenic variants in the F8 gene. The aim of this study was to identify potential pathogenic variants using targeted next generation se…
BACKGROUND Aspergillosis involving Meckel’s cave (MC) is rare. Only 5 previous case reports exist in the literature. The primary treatment for this disease is surgical debridement combined with antifungal therapy. The authors present a mini…
Recurrent urinary tract infections (rUTIs)—increasingly due to multidrug-resistant organisms—affect up to half of kidney transplant recipients (KTRs) in the first year and are associated with eGFR decline, rejection, and reduced graft survi…
Objective Infection is a major factor in morbidity and mortality among pediatric systemic lupus erythematosus (SLE) patients, particularly opportunistic infections (OI), which can result in severe clinical outcomes. There is a scarcity of d…
Case summary A 2-year-old multiparous Persian queen presented with dystocia underwent emergency transabdominal ultrasonography. Two fetuses with detectable cardiac activity were identified, and one showed severe congenital abnormalities, in…
Journal
Journal of Feline Medicine and Surgery Open Reports
Thai researchers
Kanchanarat Mankong · Kaj Chokeshaiusaha · Thanida Sananmuang
Thai institutions
Chonburi Hospital · Rajamangala University of Technology Tawan-ok
Background: Teak (Tectona grandis) leaves are rich in bioactive compounds, particularly phenolics and flavonoids, which exhibit diverse biological activities. However, their utilization in functional foods remains limited. This study assess…
Ceramothyrium (Chaetothyriaceae, Chaetothyriales) comprises mainly foliicolous fungi characterized by superficial ascomata covered by a mycelial pellicle, bitunicate asci, and hyaline, pluriseptate ascospores, and is predominantly distribut…
Journal
New Zealand Journal of Botany
Thai researchers
Gayan M. Kariyawasam · Nipuni Madhushani · Ausana Mapook · Kevin D. Hyde
BACKGROUND: Mask ventilation is a cornerstone of airway management during general anesthesia, yet the need for airway adjuncts during mask ventilation remains poorly predicted by current preoperative assessments. We aimed to identify indepe…
Abstract Purpose Postsurgical CME is a common cause of suboptimal vision following both unremarkable cataract and vitreoretinal surgery. While there is no widely accepted treatment algorithm, therapeutic options include topical nonsteroidal…
Metabolic reprogramming and lipid remodeling are increasingly recognized as key processes underlying carcinogenesis and cancer treatment failure. The liver, as a central hub for lipid metabolism and homeostasis, is particularly susceptible …
Objectives: The problem of patient safety events (PSEs) is still a significant issue in neurosurgical practice, especially when it comes to brain tumor surgery, which is associated with complex surgery and high-risk care during the postoper…
The ability of salicylic acid (SA) to control post-harvest fungal disease mango anthracnose caused by plant pathogen Colletotrichum gloeosporioides and the accompanying biochemical and metabolomic changes were studied. In vitro, C. gloeospo…
