A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals
Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.
Sue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. NewtonMahidol University · Mahidol Oxford Tropical Medicine Research Unit (MORU)
Paired samples from treatment-naïve gastric-cancer patients and controls showed substantially higher richness and diversity with mucosal brushing than biopsy. Brushing detected lower diversity and altered composition in cancer, whereas biopsy did not. Sampling method shapes microbiome signals, but causation and diagnostic utility are unproven.
Gizzard lesions in Thai chickens contained intranuclear inclusions, in-situ hybridization signal and PCR-confirmed fowl adenovirus. Hexon and fibre sequencing identified FAdV-8a strain FAdV8a_NPT_KU001_25, closer to a gizzard-tropic than an inclusion-body-hepatitis strain. Association is supported, but causation remains unproven.
A two-clinic Chiang Mai study of 150 MSM and transgender women found clinically significant depression in 5.3% of PrEP users and 13.3% of non-users. Mean depression was lower among PrEP users, while suicidal ideation occurred in 5.3% with no group difference.
An exploratory case-control study of 37 Thai adults with confirmed beta-lactam hypersensitivity identified HLA-DQA1*01:04 and HLA-DQA1*05:05 candidate signals after Bonferroni correction, with the latter stronger for immediate reactions. Small size, population controls and sensitivity-instability mean the findings are not ready for screening or drug avoidance.
Twenty male esports players were randomised to cup stacking three days weekly for four weeks or usual training. Post-intervention salivary alpha-amylase fell within the experimental group and differed significantly from controls.
Giant freshwater prawns received control diets or 10% and 20% fishmeal replacement with L. plantarum TISTR1284-fermented Leucaena for two weeks. Fermented diets increased immune markers and reduced post-A. hydrophila mortality by 26.14%, with normal intestinal morphology.
The systematic review identified 17 reports representing 15 randomised trials with 6,256 participants; 2,216 contributed to overweight subgroup analyses. The meta-analysis included 12 studies and 1,728 pregnant women with overweight. Interventions combined diet and physical activity, often with goal setting, self-monitoring and digital or remote follow-up.
A seven-country prospective cohort of 1,703 adults with HIV found Mycobacterium tuberculosis bloodstream infection predominantly among inpatients and associated it with higher 30-day mortality.
An evaluation of 1,838 stored sera from seven countries found that a second-generation Hcp1 antibody test had sensitivity ranging from 48% to 92%, with specificity varying by country and comparison group.
Thai researchersHasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Analysis of Thai national claims from 2015–2023 identified 60,916 paediatric hepatobiliary admissions. Admission rates were broadly stable and in-hospital mortality declined, while hepatic failure remained a high-risk condition.
An international expert statement spanning 22 countries reviews links among food systems, cardiometabolic health and the Sustainable Development Goals. It advocates plant-forward traditional diets rich in whole grains, legumes, vegetables, fruit, nuts and spices, with meat used sparingly.
The multicentre survey analysed 604 patients from 25 Thai hospitals between December 2023 and March 2024. SSRIs accounted for 70.2% of prescriptions, followed by TCAs at 13.9% and trazodone at 12.7%. The most common diagnoses were depressive disorders (55.0%), substance use disorders (15.2%) and psychotic disorders (13.7%). Clinicians cited limited availability (21.9%), reimbursement arrangements (36.3%) and patient finances (33.9%) as prescribing constraints.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
74IMPACT SIGNAL
Clinical Medicine
Ambient PM2.5 and respiratory tract disorder–related outpatient visits among healthcare workers: an ecological time-series study
Clinical Prognostic Factors and Survival Risk Stratification for Advanced Biliary Tract Cancer Treated with Gemcitabine-Based Palliative Chemotherapy: A Real-World Retrospective Study
Prince of Songkla University · Suan Sunandha Rajabhat University · Maejo University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine
Effects of Fine Particulate Matter on Systemic Inflammatory Biomarkers in Elderly Patients with Chronic Obstructive Pulmonary Disease Versus the Healthy Elderly: A Pilot Study
Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study
Renal Failure
Thailand-affiliated authors
Ulugbek Ochilov
Institutions
Asia Pacific International University
73IMPACT SIGNAL
Fundamental Science
L-shell X-ray production cross sections for thick silver targets induced by MeV Cuq+ ions with velocities well below the Ag L-shell Bohr velocity
Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms
Thailand-affiliated authors
J. Hussain · L.D. Yu · U. Tippawan
Institutions
Chiang Mai University · Thailand Center of Excellence in Physics
73IMPACT SIGNAL
Multidisciplinary
Effects of Reactive Footwork Training Versus Simple-Reaction Training on Lower-Extremity Motor Coordination, Dynamic Balance, and Cognitive Screening Scores in University Sport Science Students: A Pilot Randomised Controlled Trial
PHOTOLUMINESCENCE AND SCINTILLATION PROPERTIES OF CE-DOPED Lu0.5Gd0.5AlO3 SINGLE CRYSTALS GROWTH BY FLOATING ZONE METHOD
Suranaree Journal of Science and Technology
Thailand-affiliated authors
Tharittawat Tharasook · Prom Kantuptim
Institutions
Kasetsart University
73IMPACT SIGNAL
Clinical Medicine
Evaluation of pyocin activity and pyocin-related gene distribution in multidrug- and extensively drug-resistant Pseudomonas aeruginosa isolates from Thailand
Chulabhorn Royal Academy · Kasetsart University · Chulabhorn Graduate Institute · Chulabhorn Hospital
73IMPACT SIGNAL
Clinical Medicine
Foot Shape in Women With and Without Hallux Valgus Determined Using 3‐Dimensional Foot Scanning
Journal of Foot and Ankle Research
Thailand-affiliated authors
Hylton B. Menz
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine
Optimized Self‐Healing and Antioxidant Hydrogels Based on Gallic Acid–Blended Quaternized Chitosan and Oxidized Pectin for Potential Wound Dressing Applications
Coupled effects of center-of-gravity position and added mass on vortex-induced vibration and galloping-based hydrokinetic piezoelectric energy harvesting
