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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Genomic Public Health and Thalassaemia88IMPACT SIGNAL
Regional policy evidence synthesis

Thalassaemia prevention in Asia: progress, challenges, and future directions

This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured approaches, combining public awareness, carrier screening, genetic counselling, and prenatal diagnosis. Measurable success was clearest in Singapore and to a more limited extent Thailand. Many countries still face fragmented services, weak national coordination, workforce shortages, insufficient epidemiological data, and financial, technological, cultural, and social barriers. This is a regional health-system synthesis, not a comparative policy trial.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Vaccination Behaviour and Public Health89IMPACT SIGNAL
Observational cross-sectional evidence

Hepatitis B Vaccination Intention and Influencing Factors among College Students in Huanggang, Hubei, China: A Protection Motivation Theory-Based Cross-Sectional Study

This Protection Motivation Theory cross-sectional study surveyed 1,130 students aged 18–26 at three universities in Huanggang, Hubei, China, during April–May 2025. The authors dichotomized a 1–10 intention item into low scores of 1–6 and high scores of 7–10; 58.9% were in the high-intention group. In adjusted analysis, hepatitis B knowledge, vaccine knowledge, preventive behaviour, perceived severity, self-efficacy, and response efficacy were associated with higher odds of high intention, while perceived response cost was associated with lower odds. The findings identify intervention targets but do not show that changing them raises actual vaccination uptake.

Thai researchersCong Zhang · Phatcha Hirunwatthanakul · Nachalida Yukalang
Thalassaemia Epidemiology and Public Health Systems88IMPACT SIGNAL
Regional epidemiological synthesis

The Epidemiology of Thalassaemia Syndromes in Southeast Asia

This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and produce phenotypes ranging from asymptomatic carriage to lifelong transfusion dependence. Although a small set of mutations often dominates within each country, the regional spectrum is complex and population data remain incomplete. The paper highlights blood shortages, consanguinity in some settings, gender inequities, migration, and low awareness, and recommends national registries, premarital or prenatal screening, coordinated blood systems, and culturally sensitive education.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Sustainable Livestock and Agriculture89IMPACT SIGNAL
Animal-trial evidence with modeled environmental outcomes

Crude-Glycerin Leucaena Pellets Improve Goat Feed Efficiency, but Methane Reduction Is Modeled

Thai researchers tested Leucaena leucocephala pellets containing 0–15% crude glycerin in 32 male Boer × Thai native goats for 90 days. Intake fell slightly, but gain-to-feed ratio, fermentation indicators, and modeled economics improved. Methane and greenhouse-gas reductions were estimated from a stoichiometric model rather than direct emissions measurements.

Thai researchersNirandorn Nakdaeng · Sirirat Buaphan · Kanok Chaovapasee
Electric Mobility and Energy Infrastructure85IMPACT SIGNAL
Techno-economic case-study scenario analysis

Techno-Economic Assessment of EV Charging Infrastructure in Residential Buildings in Nonthaburi, Thailand

This Nonthaburi residential-building case study compared two 60-kW DC chargers, one 60-kW DC plus two 22-kW AC chargers, and four 22-kW AC chargers. Assumptions included a seven-year project, 5.5% discount rate, mean selling price of THB7.25/kWh, service time of 4, 6, or 8 hours per day, and electricity costs of THB4.50, 4.73, or 4.95/kWh, giving 27 scenarios. All three portfolios were financially feasible under the specified conditions. Two DC chargers gave the strongest return at eight hours per day and THB4.50/kWh, while four AC chargers better fit long parking durations and lower capital and maintenance costs.

Thai researchersChatchaphon Ketviriyakit · Pasura Aungkulanon · Lakkana Ruekkasaem
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
73IMPACT SIGNAL
Clinical Medicine

Dual bispecific protein engager–armed T cells targeting BCMA and B7-H3 overcome antigen heterogeneity in multiple myeloma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Thanida Chanpong · Nunghathai Sawasdee · Kamonlapat Supimon · Thanich Sangsuwannukul · Thaweesak Chieochansin · Pa‐thai Yenchitsomanus · Mutita Junking
Institutions
Siriraj Hospital
73IMPACT SIGNAL
Clinical Medicine

Evaluation of acoustic pulse and cold laser therapies for the treatment of dairy cows with subclinical mastitis under organic management conditions

Frontiers in Veterinary Science

Thailand-affiliated authors
Guy Jodarski
Institutions
Ministry of Agriculture and Cooperatives
73IMPACT SIGNAL
Multidisciplinary

Just how far off target are we? Measuring unmet pre-exposure prophylaxis need among men who have sex with men and transgender women in Asia-Pacific

Sexual Health

Thailand-affiliated authors
Nittaya Phanuphak
Institutions
Bangkok University
73IMPACT SIGNAL
Digital Health

An analogical argumentation framework for argumentative local explainers

Argument & Computation

Thailand-affiliated authors
Nguyen Duy Hung · Thanaruk Theeramunkong
Institutions
Thammasat University · The Royal College Of Anesthesiologists Of Thailand
73IMPACT SIGNAL
Clinical Medicine

Alpha-Mangostin in Acute Kidney Injury: Molecular Mechanisms, Regulated Cell Death, and Translational Opportunities

Antioxidants

Thailand-affiliated authors
Atthaphong Phongphithakchai · Nawanwat C. Pattaranggoon · Kraiyasak Wongna · Ratana Netphakdee · Aman Tedasen · Chutima Jansakun · Wiyada Kwanhian Klangbud · Jongkonnee Thanasai · Moragot Chatatikun
Institutions
Prince of Songkla University · Walailak University · Nakhon Phanom University · Mahasarakham University
73IMPACT SIGNAL
Global Public Health

Biotechnological Advances of Lactic Acid Bacteria in Maghrebian Countries: An Updated Review

Biotechnology and Applied Biochemistry

Thailand-affiliated authors
Pankaj Koirala · Nilesh Prakash Nirmal
Institutions
Mahidol University
73IMPACT SIGNAL
Energy and Materials

Fe-doped BiVO4/g-C3N4 heterojunction for efficient tetracycline degradation under low-intensity UV irradiation

Scientific Reports

Thailand-affiliated authors
Supakorn Boonyuen
Institutions
Thammasat University
73IMPACT SIGNAL
Clinical Medicine

Parametric study of electrohydrodynamic flow and heat transfer in a wind tunnel using thermochromic liquid crystals and smoke tracing

Scientific Reports

Thailand-affiliated authors
K. Wongcharee · D. Chutrakul · V. Chuwattanakul · S. Eiamsa-ard
Institutions
Mahanakorn University of Technology · King Mongkut's Institute of Technology Ladkrabang
73IMPACT SIGNAL
Clinical Medicine

Evidence- and opinion-based consensus from Delphi round 1 of the Asian aplastic anemia recommendation development

International Journal of Hematology

Thailand-affiliated authors
Surapol Issaragrisil
Institutions
Siriraj Hospital · Mahidol University
73IMPACT SIGNAL
Clinical Medicine

Severe fever with thrombocytopenia syndrome complicated by invasive pulmonary aspergillosis and septic shock: a case report highlighting the role of mNGS

Frontiers in Medicine

Thailand-affiliated authors
Mingzhi Fan
Institutions
Police General Hospital
73IMPACT SIGNAL
Environmental Engineering

Biphasic Oxidative Carboxylation of Aliphatic Olefins With H 2 O 2 to Produce Useful Cyclic Carbonates

Advanced Synthesis & Catalysis

Thailand-affiliated authors
Surajchaya Kheawmuan · Suthida Kaewsai · Wuttichai Natongchai · Pipat Na Ranong · Silvano Del Gobbo · Valerio D’Elia
Institutions
Vidyasirimedhi Institute of Science and Technology
73IMPACT SIGNAL
Clinical Medicine

Multifactorial influences on lung function in farmers: personal, occupational, and health-related factors

Journal of Environmental Science and Health Part B

Thailand-affiliated authors
Patchareeya Amput · Ajchamon Thammachai · Saisunee Konsanit · Patcharin Phrompao · Sirima Wongphon
Institutions
University of Phayao
73IMPACT SIGNAL
Environmental Engineering

A novel multi-criteria group decision-making technique in traffic flow and safety assessment using interval-valued complex spherical fuzzy soft set

Scientific Reports

Thailand-affiliated authors
Saalam Ali · Hamza Naveed
Institutions
King Mongkut's University of Technology Thonburi
73IMPACT SIGNAL
Clinical Medicine

Exploring the Reasons Behind the Low Purchase Rate of CPAP Machines Among Adult Patients With Obstructive Sleep Apnea Through Qualitative Research

Social Marketing Quarterly

Thailand-affiliated authors
Bundit Sawunyavisuth · Darunee Jongudomkarn · Kittisak Sawanyawisuth
Institutions
Khon Kaen University
73IMPACT SIGNAL
Environmental Engineering

Preharvest temperature treatments influence physiological traits, secondary metabolites, and volatile compounds in holy basil under controlled environment conditions

Scientific Reports

Thailand-affiliated authors
P. Boonkorkaew · Niafnan Hayi-asan · Akira Thongtip · Wannida Sae-Tang · Atikorn Panya · Natthaporn Phonsatta · Sujichon Thangvichien · Prapussorn Yingcharoen · Panita Chutimanukul
Institutions
Kasetsart University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
73IMPACT SIGNAL
Environmental Engineering

Nationwide and regional evidence on PM2.5-mortality in a tropical climate: Risks persist below standard and under climate extremes

Ecotoxicology and Environmental Safety

Thailand-affiliated authors
Phichet Khunthong · Panuwat Vittayapraparat · Sitthichok Puangthongthub
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN

Journal of the American Chemical Society

Thailand-affiliated authors
Cody A. Loy · Shawn E. Vinogradsky · Darci J. Trader
Institutions
Mahidol University
73IMPACT SIGNAL
Multidisciplinary

CD163+ perivascular macrophages in schizophrenia: a research framework for testing macrophage-related mechanisms

Frontiers in Psychiatry

Thailand-affiliated authors
Chavit Tunvirachaisakul · Michael Maes
Institutions
Chulalongkorn University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link