Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection
Two randomized controlled phase 3 trials are investigating the antisense oligonucleotide drug bepirovirsen in patients with chronic hepatitis B. with researchers from Chiang Mai University co-authoring
This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.
Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.
This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.
Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.
This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’
Phetchabun’s micro-elimination programme linked fingerstick anti-HCV testing, HCV-RNA confirmation, and 12-week sofosbuvir/velpatasvir treatment through primary-care and district-hospital services across all 11 districts under universal health coverage. From 2020 to April 2026, 389,547 of 400,567 targeted people were screened (97.25%); 14,845 of 18,340 anti-HCV-reactive participants received RNA confirmation (80.94%), identifying 10,996 active infections. Of 8,961 treatment-eligible patients, 8,842 received therapy (98.67%); among 6,719 evaluated at SVR12, 6,474 were cured (96.35%). The programme demonstrates province-scale test-to-treat feasibility, but not yet the incidence or mortality reductions required for elimination.
This study linked national policy, hospital systems, and provider behaviour in Indonesia, Nepal, Thailand, and Viet Nam during 2022–2023. It included 486 participants across 16 hospitals. All countries had antimicrobial-stewardship policies, but financing, enforcement, training, microbiology-data use, and inter-programme coordination were uneven. Hospitals averaged 72% on G-ASET, with tracking and reporting highest at 75% and training lowest at 66%. The two Thai hospitals scored 81.3% and 80.6% overall, yet both scored only 50% for training. These results identify actionable system gaps; they do not experimentally show that any intervention reduced antibiotic use, resistance, or mortality.
The article synthesises publications and long-running surveillance at the animal–human interface in Laos and Cambodia, covering Taenia solium, Trichinella, Streptococcus suis, rickettsiae, melioidosis, hepatitis E, and Japanese encephalitis. Its recurring message is diagnostic invisibility caused by limited laboratories and fragmented human–animal–environment systems, with risks embedded in smallholder livestock, informal slaughter, raw-meat consumption, wet markets, and animal-contact occupations. It proposes scaling abattoir, animal-sentinel, market, and environmental surveillance alongside livelihood-aware risk communication. This is a narrative synthesis, not a systematic review or one national survey, so it maps patterns and gaps rather than estimating current national burden.
Thai researchersStuart D. Blacksell · Syseng Khounsy · Jarunee Siengsanan-Lamont · Lida Kong · Jaison B. Kolenchery · Paul N. Newton · Nicholas P. J. Day
Using individual surveillance records from 2019–2021, this study examined both malaria case patterns and district factors associated with elimination across Sumatra. Of 13,386 reported cases, 71.8% were Plasmodium vivax; among 11,390 investigated cases, 15.3% were classified as imported. Multilevel models identified associations with mobile populations and clinical characteristics, while district elimination was associated with higher human development, lower historical burden, and fewer endemic neighbours. These are observational surveillance associations, not causal effects of a policy.
Thai researchersKarina D Lestari · Sri B Fajariyani · Pimphen Charoen · Saranath Lawpoolsri · Wirichada Pan-ngum
This synthesis mapped malaria evidence among migrant and mobile populations in the Greater Mekong Subregion across epidemiology, access, prevention, and health-system challenges. Of 847 records, 52 studies met inclusion criteria. Reported burden was generally low but highly variable, with hidden reservoirs from asymptomatic or submicroscopic infection in border and forest settings. Structural barriers contributed to delayed diagnosis, inconsistent prevention, and reliance on informal or cross-border care. The review exposes intervention-evaluation gaps rather than proving which approach works best.
Thai researchersPyae Linn Aung · Ajjima Thussachan · Naing Bo Bo Min · Jetsumon Sattabongkot
This Joanna Briggs Institute–guided scoping review synthesised 50 studies of resilience among family caregivers across cancer types and stages of care. The evidence was organised into risk factors, protective factors, and psychosocial or functional outcomes. Measurement tools varied substantially, and few interventions designed to strengthen family resilience had been tested empirically.
Thai researchersSiyu Yang · Xian Wang · Qing Li · Hunsa Sethabouppha
Using the Dahlem Framework, this commentary distinguishes caries control, elimination, and eradication. Global eradication is judged conceptually unattainable because caries has no single agent, interruptible transmission cycle, vaccine, or universal incidence surveillance. Elimination as a stable end to caries as a public-health problem in a defined population is presented as a plausible, measurable goal.
Thai researchersHabib Benzian
BIBLIOGRAPHIC RESEARCH WATCHLIST
Bibliographic research records
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
70IMPACT SIGNAL
Clinical Medicine
A hypothesis-driven perspective on GLP-1R-β-catenin pathway crosstalk in astrocyte plasticity and endogenous neural repair
Biomedicine & Pharmacotherapy
Thailand-affiliated authors
Sudichhya Tamrakar · Laurence S. Pe · Jiraporn Panmanee · Sujira Mukda
Institutions
Mahidol University
70IMPACT SIGNAL
Multidisciplinary
Slaughter blood-derived bioactive peptides: structure-function relationships, species-specific bioactivities, gastrointestinal stability, and sustainable applications in food systems
Journal of Applied Economics and Management Strategy
Thailand-affiliated authors
จันทร์จิรา พันธ์แจ้ง · จุฑามาศ ทวีไพบูลย์วงษ์
Institutions
Kasetsart University
70IMPACT SIGNAL
Global Public Health
Critical Success Factors for Enhancing Performance of Agile Humanitarian Logistics Using CVI Method: Evidence from the 2024 Bangladesh Flood
Logistics
Thailand-affiliated authors
Israt Jahan Hridi · Chawis Boonmee
Institutions
Chiang Mai University
70IMPACT SIGNAL
Environmental Engineering
Learning From Senior Leaders as a Catalyst for Innovativeness: The Differential Contributions of Supervisors, Coaches, and Mentors Under Varying Task Uncertainty
Creativity and Innovation Management
Thailand-affiliated authors
Ei Ei Phyo · Yuosre F. Badir
Institutions
Asian Institute of Technology
70IMPACT SIGNAL
Environmental Engineering
Exploring the role of CRISPR in advancing space biotechnology: challenges and solutions for human survival beyond earth
Frontiers in Bioengineering and Biotechnology
Thailand-affiliated authors
Ubaid Ahmad
Institutions
Chiang Mai University
70IMPACT SIGNAL
Multidisciplinary
Ethanol production from oil palm empty fruit bunch fiber prepared through pretreatment with sodium hydroxide under optimized conditions
Nova Biotechnologica et Chimica
Thailand-affiliated authors
Rama Mohan Poludasu · Boonsawang Piyarat
Institutions
Prince of Songkla University
70IMPACT SIGNAL
Multidisciplinary
Didiclis pseudobisulcata (Selaginellaceae), a new species of the Bisulcata group from northern Thailand and southwest China
PhytoKeys
Thailand-affiliated authors
Rossarin Pollawatn · Sahut Chantanaorrapint
Institutions
Chulalongkorn University · Prince of Songkla University
P1.090. Innovative Push Percutaneous Endoscopic Gastrostomy Using Thread-Through-Trap and Alken Dilator in Advanced Esophageal and Head and Neck Cancer
Diseases of the Esophagus
Thailand-affiliated authors
Prasit Mahawongkajit · Worapong Anuponganan
Institutions
Thammasat University
70IMPACT SIGNAL
Clinical Medicine
Ankle Biomechanics and Muscle Activation During Repeated Single-Leg Lateral Hopping: Effects of Speed and Distance
Double zoonosis: Parinaud oculoglandular syndrome from sporotrichosis and follicular conjunctivitis from Moraxella osloensis, a zoonotic co-infection from our feline friend
Thammasat University Hospital · Thammasat University · Rajabhat Rajanagarindra University
70IMPACT SIGNAL
Global Public Health
Genetic Variation and Demographic History of Green Weevil Hypomeces pulviger (Herbst, 1795) (Coleoptera: Curculionidae) in Thailand Examined by Mitochondrial DNA Sequences
Mahasarakham University · Naresuan University · Maejo University · Thammasat University
70IMPACT SIGNAL
Clinical Medicine
Pharmacokinetic modeling to support WHO-weight band dosing of a new pediatric darunavir/ritonavir (120/20 mg) fixed-dose combination tablet for children at least 3 years old and weighing 10 to less than 35 kg
JAIDS Journal of Acquired Immune Deficiency Syndromes
Thailand-affiliated authors
Marc Lallemant · Tim R. Cressey
Institutions
Chiang Mai University
70IMPACT SIGNAL
Clinical Medicine
Multi-Target Neuroprotective Effects of Cordycepin and Adenosine from Cordyceps militaris Against Amyloid-β-Induced Neurotoxicity