Effect of gonadotropin supplementation on oocyte maturation and mean oocyte diameter in rescue IVM: a prospective sibling-oocyte study
A prospective sibling-oocyte study in 29 patients compared 104 immature oocytes. Adding FSH and LH increased nuclear maturation from 30.77% to 51.92%, adjusted OR 3.28, but did not shift mean oocyte diameter toward the range associated with good-quality blastocysts. Fertilisation, pregnancy and live-birth benefit remain unproven.