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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Restoring Culturally Essential Floor-Sitting in Transfemoral Prosthesis Users: A Six-Week Pilot Randomized Within-Subject Trial

A pilot randomised within-subject trial in 14 unilateral transfemoral prosthesis users compared a low-profile, femoral-adducted Asian Transfemoral Socket with each participant's usual socket after six weeks of ATS use. Twelve participants attained cross-legged sitting and six additional participants attained side-sitting with ATS, alongside comfort and quality-of-life signals. Six-minute walking distance, four-square-step balance and daily steps did not differ significantly; the small sample could not exclude clinically important harm.

Thai researchersNatthawan Sutthison · Nang Myat Myat Moe · Yasmin Nutchamlong · Marisa Amattayakul · Mathurin Rairat · Woratee Dacharux · Kazuhiko Sasaki
Clinical Medicine89IMPACT SIGNAL
Global potential

Effects of a Home-Based Fall Prevention Program in Older Lower Limb Prosthesis Users: A Randomized Controlled Trial

A randomised controlled trial assigned 44 older lower-limb prosthesis users to usual care or education plus 16 home exercises three times weekly for eight weeks; 41 completed follow-up. Change in Timed Up and Go did not differ between groups, nor did static balance or balance confidence. No falls were reported during the study, but the sample and follow-up were too small to establish fall prevention or definitive lack of benefit. The null finding applies to this relatively high-mobility study population.

Thai researchersPrawina Sakulkosol · Pieter U Dijkstra · Kazuhiko Sasaki · Jutamanee Poonsiri
Genomic Public Health and Thalassaemia88IMPACT SIGNAL
Regional policy evidence synthesis

Thalassaemia prevention in Asia: progress, challenges, and future directions

This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured approaches, combining public awareness, carrier screening, genetic counselling, and prenatal diagnosis. Measurable success was clearest in Singapore and to a more limited extent Thailand. Many countries still face fragmented services, weak national coordination, workforce shortages, insufficient epidemiological data, and financial, technological, cultural, and social barriers. This is a regional health-system synthesis, not a comparative policy trial.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Vaccination Behaviour and Public Health89IMPACT SIGNAL
Observational cross-sectional evidence

Hepatitis B Vaccination Intention and Influencing Factors among College Students in Huanggang, Hubei, China: A Protection Motivation Theory-Based Cross-Sectional Study

This Protection Motivation Theory cross-sectional study surveyed 1,130 students aged 18–26 at three universities in Huanggang, Hubei, China, during April–May 2025. The authors dichotomized a 1–10 intention item into low scores of 1–6 and high scores of 7–10; 58.9% were in the high-intention group. In adjusted analysis, hepatitis B knowledge, vaccine knowledge, preventive behaviour, perceived severity, self-efficacy, and response efficacy were associated with higher odds of high intention, while perceived response cost was associated with lower odds. The findings identify intervention targets but do not show that changing them raises actual vaccination uptake.

Thai researchersCong Zhang · Phatcha Hirunwatthanakul · Nachalida Yukalang
Thalassaemia Epidemiology and Public Health Systems88IMPACT SIGNAL
Regional epidemiological synthesis

The Epidemiology of Thalassaemia Syndromes in Southeast Asia

This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and produce phenotypes ranging from asymptomatic carriage to lifelong transfusion dependence. Although a small set of mutations often dominates within each country, the regional spectrum is complex and population data remain incomplete. The paper highlights blood shortages, consanguinity in some settings, gender inequities, migration, and low awareness, and recommends national registries, premarital or prenatal screening, coordinated blood systems, and culturally sensitive education.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Sustainable Livestock and Agriculture89IMPACT SIGNAL
Animal-trial evidence with modeled environmental outcomes

Crude-Glycerin Leucaena Pellets Improve Goat Feed Efficiency, but Methane Reduction Is Modeled

Thai researchers tested Leucaena leucocephala pellets containing 0–15% crude glycerin in 32 male Boer × Thai native goats for 90 days. Intake fell slightly, but gain-to-feed ratio, fermentation indicators, and modeled economics improved. Methane and greenhouse-gas reductions were estimated from a stoichiometric model rather than direct emissions measurements.

Thai researchersNirandorn Nakdaeng · Sirirat Buaphan · Kanok Chaovapasee
Electric Mobility and Energy Infrastructure85IMPACT SIGNAL
Techno-economic case-study scenario analysis

Techno-Economic Assessment of EV Charging Infrastructure in Residential Buildings in Nonthaburi, Thailand

This Nonthaburi residential-building case study compared two 60-kW DC chargers, one 60-kW DC plus two 22-kW AC chargers, and four 22-kW AC chargers. Assumptions included a seven-year project, 5.5% discount rate, mean selling price of THB7.25/kWh, service time of 4, 6, or 8 hours per day, and electricity costs of THB4.50, 4.73, or 4.95/kWh, giving 27 scenarios. All three portfolios were financially feasible under the specified conditions. Two DC chargers gave the strongest return at eight hours per day and THB4.50/kWh, while four AC chargers better fit long parking durations and lower capital and maintenance costs.

Thai researchersChatchaphon Ketviriyakit · Pasura Aungkulanon · Lakkana Ruekkasaem
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of tocilizumab for refractory postsurgical cystoid macular edema

Journal of Ophthalmic Inflammation and Infection

Thailand-affiliated authors
Prapatsorn Ongpalakorn
Institutions
Nopparat Rajathanee Hospital
77IMPACT SIGNAL
Multidisciplinary

A Hierarchical Computer Vision Framework for Continuous Dairy Cow Behavior Monitoring in an Obstructed Free-Stall Barns

Smart Agricultural Technology

Thailand-affiliated authors
Aqeel Raza · Kumail Abbas · H. Hogeveen · Chaidate Inchaisri
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Metabolomic and lipidomic analyses reveal phosphatidylcholine–lysophosphatidylcholine axis alterations in sorafenib-persistent hepatocellular carcinoma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Meng Chieh Yang · Nichawadee Sandech · Sucheewin Krobthong · Likit Rangsirattanakul · Wisuit Pradidarcheep · Arnatchai Maiuthed
Institutions
Srinakharinwirot University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Patient safety events and outcomes in brain tumor surgery : A retrospective cohort study

Journal of Neurosciences in Rural Practice

Thailand-affiliated authors
Kanisorn Sungkaro · Pannawit Chumchue · Thara Tunthanathip · Supaporn Sainamsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a drug–herb interaction alert system integrated into a hospital electronic health record

Pharmacia

Thailand-affiliated authors
Thanatcha Songmuang · Ananya Songmuang · Chonladda Pitchayajittipong · Teeraporn Sadira Supapaan
Institutions
Warin Chamrap Hospital · Ubon Ratchathani University
77IMPACT SIGNAL
Clinical Medicine

Association of adipocyte hypertrophy and ultrasound severity score in lymphedematous limb: a cross-sectional study

Scientific Reports

Thailand-affiliated authors
Parkpoom Piyaman · Panitta Sitthinamsuwan · Sirin Apichonbancha · Nutcha Yodrabum
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Phosphoprotein-enriched proteomics identifies heat shock cognate 71 protein as a host factor supporting chikungunya virus replication in macrophages

Scientific Reports

Thailand-affiliated authors
Nattaya Kamchompoo · Songkran Thongon · Artittaya Athipanyasilp · Tipparat Thiangtrongjit · Kawin Chantima · Onrapak Reamtong · Kobporn Boonnak
Institutions
Siriraj Hospital · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Multidisciplinary providers’ perspectives on timely predialysis arteriovenous access preparation: An exploratory mixed-methods study in upper Northern Thailand

PLoS ONE

Thailand-affiliated authors
Amaraporn Rerkasem · Kochaphan Phirom · Pak Thaichana · Prit Kusirisin · Puntapong Taruangsri · Suwinai Saengyo · Sasinat Pongtam · Wanicha Pungchompoo · Kittipan Rerkasem
Institutions
Chiang Mai University · Nakornping Hospital · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases

Biology

Thailand-affiliated authors
Chalerm Liwsrisakun · Athavudh Deesomchok · Chaicharn Pothirat · Warawut Chaiwong
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort)

Renal Failure

Thailand-affiliated authors
Wanjak Pongsittisak · Jeerath Phannajit · Wonngarm Kittanamongkolchai · Theerasak Tangwonglert · Thawee Chanchairujira · Kraiwiporn Kiattisunthorn · Kornchanok Vareesangthip · Bongkod Surattichaiyakul · Arkom Nongnuch · Surachet Vongsanim · Pantipa Tonsawan · Pornpen Sangthawan · Siribha Changsirikulchai · Phanupong Phutrakool · Peerapat Thanapongsatorn · Pichaya Tantiyavarong · Talerngsak Kanjanabuch · Khajohn Tiranathanagul · Suchai Sritippayawan · Suree Yoowannakul · Vuddhidej Ophascharoensuk · Paweena Susantitaphong
Institutions
Navamindradhiraj University · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Phramongkutklao Hospital · Siriraj Hospital · Rajamangala Institute of kidney disease · Mahidol University · Ramathibodi Hospital · Chiang Mai University · Khon Kaen University · Prince of Songkla University · Srinakharinwirot University · Thammasat University · Bhumibol Adulyadej Hospital
77IMPACT SIGNAL
Clinical Medicine

Elevated Lipoprotein(a) in Asian Populations and its Implications for Cardiovascular Disease

JACC Asia

Thailand-affiliated authors
Rungroj Krittayaphong
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Multidisciplinary

Multiobjective V H H discovery through integrated high-throughput screening and AlphaFold3-guided structural prioritization

Science Advances

Thailand-affiliated authors
Suthimon Thumtecho
Institutions
King Chulalongkorn Memorial Hospital
77IMPACT SIGNAL
Environmental Engineering

Growth, Antioxidant, and Physiological Responses Associated with Tuber Yield in Cassava Under Irrigation and Late-Season Drought Conditions in a Tropical Savanna Climate

Plants

Thailand-affiliated authors
Supranee Santanoo · Passamon Ittipong · Nimitr Vorasoot · Sanun Jogloy · Kochaphan Vongcharoen · Piyada Theerakulpisut · Poramate Banterng
Institutions
Khon Kaen University · Kalasin University
77IMPACT SIGNAL
Clinical Medicine

Reduced Plasma Cardiac Myosin-Binding Protein-C Concentrations in Cats with Hypertrophic Cardiomyopathy: Evidence from Chronic, Treated Disease

Animals

Thailand-affiliated authors
Nutcha Tanakwang · Natcha Sakunasing · Sarawut Kumphune · Raktham Mektrirat · Kannika Na Lampang · Chavalit Boonyapakorn · Wanpitak Pongkan
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Computational Investigation of S781F Mutation-Induced Remodeling of the Staphylococcal Nuclease Domain-Containing Protein 1–Argonaute 2 Interface

International Journal of Molecular Sciences

Thailand-affiliated authors
Jittasak Khowsathit · Manu Deeudom · Warinda Prommachote · Bishant Pokharel · Pimpisid Koonyosying · Somdet Srichairatanakool
Institutions
Chiang Mai University · Walailak University
77IMPACT SIGNAL
Clinical Medicine

Parental Experiences of Anesthesia Consent for Children with Retinoblastoma Undergoing Ophthalmologic Examinations under Anesthesia: A Qualitative Interview Study

Journal of Health Science and Medical Research

Thailand-affiliated authors
Sutida Boonkamjad · Kholid Karunan · Darunee Sripadungkul · Kotchakron Palachewa · Laksanawadee Chairatana
Institutions
Khon Kaen University · Boromarajonani College of Nursing
77IMPACT SIGNAL
Clinical Medicine

Revisiting Asymptomatic Pulmonary Tuberculosis with Cavitary Lesion Detected During Routine Chest Radiography in a Healthcare Worker: A Case in Point

THE BANGKOK MEDICAL JOURNAL

Thailand-affiliated authors
Charnarong Khajornsuwan · Narongpon Dumavibhat · Supakorn Chansaengpetch · Wipaporn Homchan · Nisa Muangman · Krittachat Butnian · Benjawan Inkham · Tirathat Virojskulchai · Thirajit Boonsaen · Pennapa Kaweewongprasert · Sitthiphon Bunman · Sichon Luerithiphong
Institutions
Chulalongkorn University · Siriraj Hospital · Mahidol University · Thammasat University
77IMPACT SIGNAL
Clinical Medicine

Effect of derotation boot versus skin traction on pain in patients with intertrochanteric fractures a randomized controlled trial

Scientific Reports

Thailand-affiliated authors
Sanzhar Artykbay · Saran Tantavisut · Chavarin Amarase · Pariwat Taweekitikul · Techit Leelasestaporn · Supacheep Viriyakorkitkul
Institutions
Chulalongkorn University · Queen Savang Vadhana Memorial Hospital · King Mongkut Memorial Hospital
77IMPACT SIGNAL
Environmental Engineering

Extraction and Reuse of Disperse Dyes from Polyethylene Terephthalate (PET) Fabric in a Subsequent Dyeing Process

Textiles

Thailand-affiliated authors
Jantip Setthayanond · Potjanart Suwanruji · Piyaporn Kampeerapappun · Thitinun Monhaphol Karpkird · Porntip Tooptompong
Institutions
Kasetsart University · Rajamangala University of Technology Krungthep
77IMPACT SIGNAL
Energy and Materials

Fe-Doped TiO2/Hard Carbon-Coated PLA 3D-Printed Structures for Synergistic Adsorption–Photocatalytic Removal of Methylene Blue and Tetracycline in Water

Catalysts

Thailand-affiliated authors
Oratai Jongprateep · Pohnpairin Saengkla · Chanakan Permmit · Tyme Hetrakul · Parichart CHAUM · Benjaporn Inseemeesak · Angsuthorn Ngamprasit · Kulanit Lanamkham · Natthaphong Thanawatchaimongkol · Jittikorn Sakul-ala · Jirayu Kongtip · Ratchatee Techapiesancharoenkij · Gasidit Panomsuwan
Institutions
Kasetsart University · Bangkok University
77IMPACT SIGNAL
Clinical Medicine

Adjunctive Cold Atmospheric Plasma Therapy for Tracheostomy Wound Healing in Critically Ill Patients: A Pilot Randomised Controlled Trial

International Wound Journal

Thailand-affiliated authors
Lalita Jaingim · Kanlayanee Sittiwat · Kotchawan Nongyam · Konlawij Trongtrakul
Institutions
Chiang Mai University · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Evaluating the diagnostic value of shear wave elastography in early systemic sclerosis: a case-control study

Scientific Reports

Thailand-affiliated authors
Punthip Thammaroj · Sudarat Hongchokthavee · Chawiporn Muktabhant · Chingching Foocharoen · Wiraphong Sucharit
Institutions
Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

PAH genotypes and their impact on sapropterin responsiveness in Thai patients with phenylalanine hydroxylase deficiency

˜The œItalian Journal of Pediatrics/Italian journal of pediatrics

Thailand-affiliated authors
Dhachdanai Dhachpramuk · N. Densupsoontorn · Napat Sittanomai · Khunton Wichajarn · Thipwimol Tim‐Aroon · Duangrurdee Wattanasirichaigoon · Lukana Ngiwsara · Somporn Liammongkolkul · Hathaichanok Rukprayoon · Sudarat Sirisakpanit · Souwaluck Ratanamalaya · Nithiwat Vatanavicharn
Institutions
Siriraj Hospital · Mahidol University · Khon Kaen University · Ramathibodi Hospital · Chulabhorn Research Institute
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link