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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
HIV, Ageing and Metabolic Health89IMPACT SIGNAL
Longitudinal observational cohort evidence

Metabolic Dysfunction‐Associated Steatohepatitis and the Progression of Cognitive Decline in Older Thai People With HIV

This prospective HIV-NAT cohort in Bangkok followed 291 people with HIV aged at least 50 years from 2015–2024; 60 participants, or 20.6%, met non-invasive criteria for MASH at baseline. Over a median 5.9 years, baseline MASH was associated with steeper decline in Thai-validated MoCA scores after adjustment for multiple metabolic, social, and HIV-related factors, whereas MASLD without the MASH signal was not associated with decline. The findings support integrated liver and cognitive surveillance but do not show that treating MASH prevents cognitive deterioration.

Thai researchersKatekarn Porkaew · Akarin Hiransuthikul · Win Min Han · Tanakorn Apornpong · Sasiwimol Ubolyam · Stephen John Kerr · Anchalee Avihingsanon
Sports Science and Youth Development88IMPACT SIGNAL
Exploratory cross-sectional evidence

Early neuromuscular and cognitive signatures in high-performance young male Muay Thai athletes

Researchers assessed 215 high-performance male Muay Thai athletes aged 8–18 over five days and compared four age groups. Anthropometry, biological maturation, maximal strength, and several cognitive measures improved with age, while limb asymmetry, fatigue indices, Nordic hamstring performance, lower-limb dynamic strength index, and upper-limb push-up force did not differ by age. PCA suggested age-specific multidimensional profiles, but cross-sectional data do not prove an effect of age or training and do not constitute a validated talent-selection model.

Thai researchersPhornpot Chainok · Naruepon Vongjaturapat · Nattasit Suwannawat · Atcharat Yongtawee
Patient-Reported Outcome Measurement86IMPACT SIGNAL
Qualitative evidence from patient experience

Measuring what matters: Evaluating quality of life instruments through the eyes of people with Parkinson's disease

Researchers asked 31 people living with Parkinson's disease to complete eight quality-of-life instruments and then used semi-structured interviews to explore what helped or hindered meaningful reporting. Participants favored broad response options, attention to personal, emotional, and practical effects, clear and specific language, and a balance of positive and negative questions. The study centers lived experience in instrument refinement but does not establish which questionnaire has the best validity, reliability, or responsiveness.

Thai researchersOnanong Phokaewvarangkul
Business, Marketing and Consumer Behaviour86IMPACT SIGNAL
Survey and configurational-model evidence

Balancing continuity and relevance: Innovation-nostalgia configurations in time-honored brand revitalization

Revitalizing a time-honored brand requires continuity of identity alongside present-day relevance. The study analyzed 404 firm-side respondents from 76 enterprises and 536 consumers in Southwestern China using PLS-SEM and fsQCA. Innovation and nostalgia interacted positively only in the firm model; both were positively associated on the consumer side, where nostalgia was stronger. Set-theoretic analysis identified overlapping configurations and three balancing logics, framing revitalization as a multi-actor process rather than a universal formula.

Thai researchersXiangyu Li · Danaikrit Inthurit · Surachai Kungwon · Nirote Sinnarong
Sustainable Tourism and Climate Risk85IMPACT SIGNAL
Cross-sectional structural and configurational evidence

Revisit Intention Under Climate Risk in Island Tourism: Structural and Configurational Evidence from PLS-SEM and fsQCA

The study examines how perceived island-climate risk, destination climate resilience, tourism climate-service usefulness, and destination trust combine in relation to intention to revisit Phuket. An on-site survey of 480 Chinese tourists was analyzed using both PLS-SEM and fsQCA. The structural model explained 74.6% of variance in revisit intention: perceived climate risk was negatively associated, the other three constructs were positively associated, and trust had the strongest direct association. The configurational analysis identified multiple routes to high and low intention. All results concern cross-sectional self-reported intention, not proof that an intervention causes actual return travel.

Thai researchersXinda Yang · Sirichai Preudhikulpradab · Lalida Arphawatthanasakul
Health Professions Education and Research Equity85IMPACT SIGNAL
Global bibliometric and network analysis

Moving towards decolonizing health professions education research: an analysis of global network patterns and equity implications

An all-Thai team analyzed co-authorship structures in five leading Q1 health-professions-education journals from 2015 through 2024, covering 13,187 publications, 45,366 authors, and affiliations in 162 countries. Annual output grew 2.7-fold and distinct authors 3.7-fold. High-income-country-only publications fell from 86% to 63%, while non-high-income-only publications rose from 6% to 26%. The network became broader and more connected, yet the United States, United Kingdom, and Canada remained central, and low-income-country collaboration was more often routed through high-income partners than through regionally led networks.

Thai researchersPeerasit Sitthirat · Seksan Yoadsanit · Phuphinyo Limchantra · Kanjaree Suppawittaya · Suttithan Suwannoppakun · Piwat Suppawittaya · Phanuwich Kaewkamjornchai · Somsak Chunharas
Healthcare Operations and Decision Support85IMPACT SIGNAL
Computational simulation evidence

An Integrated Intelligent Decision Support System Combining Stochastic Programming and Queuing Theory for Dynamic Triage of Surgical Critical Care Patients to Prevent Postoperative Complications in Healthcare Business Operation

The authors developed SQDSS, combining two-stage stochastic programming with multi-class priority queueing to triage surgical critical-care patients under uncertain arrivals, changing acuity, and deterioration while waiting. Across 48 synthetic datasets, comparisons with first-come-first-served and a fixed-severity rule showed about 22.8% shorter high-acuity waits, 16% greater bed utilization, roughly 28% less queue overflow, and roughly 18% fewer simulated complications. Benefits were greatest under surge and trauma-dominant conditions. No real-patient data or implementation trial were used, so these results demonstrate modeled feasibility rather than clinical effectiveness.

Thai researchersJarun Bootdachi · Parichat Wonggom · Wiphawadee Potisopha
Adolescent Mental Health and Measurement85IMPACT SIGNAL
Psychometric validation

Psychometric Properties of the Revised Thai Rosenberg Self-Esteem Scale (r-TRSES) in Adolescents: Confirmatory Factor Analysis and Rasch Modeling

The study evaluates a culturally reworded Thai Rosenberg Self-Esteem Scale in 443 boarding-school students. Confirmatory factor analysis supported a bifactor structure with a dominant general self-esteem factor and residual wording-related variance. Rasch analysis supported essential unidimensionality, acceptable item fit, strong reliability, and ordered response thresholds. No item exceeded the prespecified threshold for sex differential item functioning. Scores correlated positively with resilience (r=0.589) and negatively with depressive symptoms (r=-0.601), but precision declined among adolescents with higher self-esteem and broader replication remains necessary.

Thai researchersJustin DeMaranville · Peerapat Naprung · Supisara Prompila · Nahathai Wongpakaran · Tinakon Wongpakaran
Clinical-Trial Systems and Research Capacity88IMPACT SIGNAL
Expert-workshop open letter; version 1 awaiting peer review

Strengthening Sustainable Clinical Trial Models for Greater Health Impact: Expert Discussion from the Annual Wellcome Major International Programme Regional Meeting 2024

This open letter synthesizes the 2024 Wellcome Major International Programmes meeting, which brought together research-institution representatives from Africa, Asia, and the United Kingdom. Participants identified limited clinical-trial literacy, unstable funding, workforce recruitment and retention, inequitable partnerships, ethics and regulatory bottlenecks, operational inefficiencies, and barriers in remote settings. Proposed responses included locally led agendas, diversified funding, workforce development, stronger community and regulator engagement, platform, adaptive and decentralized trials, shared monitoring, and interoperable data systems. The meeting agreed to explore a formal MIPs alliance, but the paper does not show that the alliance has yet delivered operational or health outcomes.

Thai researchersNicholas P J Day · Nicholas J White
Generative AI and Higher Education85IMPACT SIGNAL
Cross-sectional PLS-SEM evidence

Extending UTAUT with Metacognition and Self-Regulation: Evidence on Generative AI Use among University Students

A survey of 451 students at seven Thai Rajabhat universities extended UTAUT by positioning metacognitive awareness and self-regulated learning between technology-acceptance determinants and GenAI-use intention, with intention predicting self-reported use of GenAI as a cognitive partner. Facilitating conditions had the strongest associations with metacognition and self-regulation but no significant direct association with intention; the significant indirect path ran through metacognition. Social influence was the strongest direct predictor of intention, followed by metacognition, while effort expectancy and self-regulated learning did not predict intention in this model.

Thai researchersNatthawan Phoonson · Thada Jantakoon · Rukthin Laoha
Geriatric and Transitional Care85IMPACT SIGNAL
Prospective observational evidence

Nearly Two-Thirds of Frail Older Adults Had an Unplanned Hospital Return Within Six Months

An interim prospective secondary analysis from a parent trial at one university hospital followed 170 frail older adults after medical-ward discharge. A broad composite of emergency visits, unplanned outpatient visits, and readmissions rose from 34.7% at one month to 64.7% at six months. Better nutritional status was associated with lower return odds, and returners had higher direct medical costs. The observational analysis does not show that nutritional intervention prevents return.

Thai researchersPatumporn Suraarunsumrit · Maytinee Srisubin · Sutisa Pitiyarn · Ponnapa Petchthai · Dariya Tantiameorn · Chaloemphon Thedpun · Sunit Jarungjitaree · Kotchamon Sukyoyot · Unchana Sura-amonrattana · Varalak Srinonprasert · Titima Wongviriyawong
HIV Prevention and Health Equity92IMPACT SIGNAL
Cross-national cross-sectional evidence

PrEP Use and Willingness Cascades Among Transgender Women in 11 Asian Countries: Findings From the PrEP APPEAL Cross-Sectional Online Survey

The 2022 PrEP APPEAL online survey included 1,178 transgender women in 11 Asian countries. Awareness was 80.0%; among those aware, 62.6% had ever used PrEP, and 78.1% of ever-users were current users. Among higher-risk PrEP-naïve respondents, 60.0% were willing to use it, but only 34.0% of those willing would pay. Healthcare discrimination was associated with lower lifetime use; causality cannot be inferred.

Thai researchersRena Janamnuaysook · Hua Boonyapisomparn · Nittaya Phanuphak
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Development and validation of a prognostic gene expression model for second primary malignancy in head and neck squamous cell carcinoma

Scientific Reports

Thailand-affiliated authors
Rungsinee Suksakulchai · Nutchavadee Vorasan · Lalida Arsa · Artit Jinawath · Warut Pongsapich · Tauangtham Anekpuritanang · Somkiat Sunpaweravong · Nuttapong Ngamphaiboon · Bhoom Suktitipat · Natini Jinawath
Institutions
Mahidol University · Ramathibodi Hospital · Siriraj Hospital · Prince of Songkla University · Ramathibodi Chakri Naruebodindra Hospital
77IMPACT SIGNAL
Clinical Medicine

Prediction models for early-onset atopic dermatitis in infancy: a prospective cohort study

Allergy Asthma and Clinical Immunology

Thailand-affiliated authors
Eakchalerm Eakpanit · Kamolwish Laoprasopwattan · Pasuree Sangsupawanich · Nattaporn Tassanakijpanich · Kemmapon Chumchuen · Vanlaya Koosakulchai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and Application of a Dual-Fluorescent Reporter Assay for Feline Infectious Peritonitis Virus RNA-Dependent RNA Polymerase Inhibitor Screening

International Journal of Molecular Sciences

Thailand-affiliated authors
Ploypailin Semkum · Varanya Lueangaramkul · Supichaya Jiwattanasap · Natjira Mana · Nantawan Phecharat · Porntippa Lekcharoensuk · Sirin Theerawatanasirikul
Institutions
Kasetsart University
77IMPACT SIGNAL
Environmental Engineering

Water Footprint of Local Herbs in Thailand Using the Water Footprint Network Methodology

Nature Environment and Pollution Technology

Thailand-affiliated authors
Harnpon Phungrassami · Phairat Usubharatana
Institutions
Thammasat University
77IMPACT SIGNAL
Clinical Medicine

The Citrus Flavonoid Naringin Confers Neuroprotection Against Cerebral Ischemia by Enhancing Endogenous Antioxidant Capacity and Suppressing Neuroinflammation

Foods

Thailand-affiliated authors
Ratchaniporn Kongsui · Nut Palachai · Araya Supawat · Sitthisak Thongrong · Jinatta Jittiwat
Institutions
University of Phayao · Mahasarakham University
77IMPACT SIGNAL
Fundamental Science

The Gravitational-wave Optical Transient Observer (GOTO) Fast Analysis and Spectroscopy of Transients (FAST) Surveys

Monthly Notices of the Royal Astronomical Society

Thailand-affiliated authors
U Sawangwit · K Noysena
Institutions
National Astronomical Research Institute of Thailand
77IMPACT SIGNAL
Clinical Medicine

Postpartum fever in sows housed in a temporary-confinement farrowing system under tropical conditions: risk factors and associations with feed intake, vaginal discharge, colostrum production, and hematological profiles

Porcine Health Management

Thailand-affiliated authors
Natnicha Thamma · Phatcharasri Dusadipong · Witchayanan Chakkrathon · Sunarin Robkob · Awatsada Malila · Tip-Apa Akkhaphan · Preechaphon Taechamaeteekul · Padet Tummaruk
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Validated QuEChERS–HPLC–UV Method for Quantification of Cannabidiol in Pharmaceutical Nanoformulations

ChemPlusChem

Thailand-affiliated authors
Pimpisa Chaobon · Phichaporn Bunwatcharaphansakun · Gehsirinnad Supattanachote · Katawut Namdee · Thitaphat Ngernsutivorakul
Institutions
Kasetsart University · National Nanotechnology Center · Ministry of Higher Education, Science, Research and Innovation
77IMPACT SIGNAL
Global Public Health

Immunogenicity and safety of high-dose versus double-dose quadrivalent inactivated influenza vaccine in adult kidney transplant recipients: a randomized controlled trial (2023)

The Lancet Regional Health - Southeast Asia

Thailand-affiliated authors
Thanachote Arayanumas · Kobporn Boonnak · Surasak Kantachuvesiri · Sarinya Boongird · Sasisopin Kiertiburanakul · Jackrapong Bruminhent
Institutions
Mahidol University · Ramathibodi Hospital · Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Immunomodulatory Potential of KSTM in Activating Natural Killer Cells for Cancer Cell Elimination

Pharmaceuticals

Thailand-affiliated authors
Tanyarat Pianmak · Aussara Panya · Natthanich Boonsatit · Lueacha Tabtimmai · Kiattawee Choowongkomon
Institutions
Kasetsart University · Chiang Mai University · King Mongkut's University of Technology North Bangkok
77IMPACT SIGNAL
Clinical Medicine

Clinical Characteristics, Antimicrobial Susceptibility, Treatment, and Outcomes of Achromobacter Bacteremia: A 20-Year Retrospective Cohort Study

Antibiotics

Thailand-affiliated authors
Tawin Khaimook · Pisud Siripaitoon · Sarunyou Chusri · Narongdet Kositpantawong · Siripen Kanchanasuwan · Sorawit Chittrakarn · Nattapat Sangkakul · Nonthanat Tongsengkee
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Clinical characteristics and species distribution of Mycobacterium fortuitum complex isolates

BMC Microbiology

Thailand-affiliated authors
Yonita Yuliani · Kanphai Wongjarit · Prangwalai Chanchaem · Kasidis Phongkhun · Suthida Visedthorn · Suthidee Petsong · Pornchai Kaewsapsak · Sunchai Payungporn · Suwatchareeporn Rotcheewaphan
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Environmental Correlates of Opisthorchis viverrini Infection-Free Zones: A Comparative Machine Learning Approach Using Satellite-Derived Indices

Symmetry

Thailand-affiliated authors
Nutchanat Buasri · Patiwat Littidej · Benjamabhorn Pumhirunroj
Institutions
Mahasarakham University · Sakon Nakhon Rajabhat University
77IMPACT SIGNAL
Clinical Medicine

Prognostic significance of post-treatment total lymphocyte count in locally advanced cervical cancer after definitive chemoradiotherapy

BMC Women s Health

Thailand-affiliated authors
Chutisa Phuvaruttanakul · Kittinun Leetanaporn · Rakchai Buhachat · Ingporn Jiamset · Ekasak Thiangphak
Institutions
Prince of Songkla University · Songklanagarind Hospital
77IMPACT SIGNAL
Clinical Medicine

Factors associated with extravasation severity in Thai patients receiving noncytotoxic intravenous infusions: An observational study

Belitung Nursing Journal

Thailand-affiliated authors
Thitiporn Pathomjaruwat · Borwarnluck Thongthawee · Padcha Pongcharoen · Charturong Tantibundhit
Institutions
Thammasat University · Rangsit University
77IMPACT SIGNAL
Clinical Medicine

FACTORS ASSOCIATED WITH HOSPITAL ARRIVAL TIME IN ISCHEMIC STROKE PATIENTS AT BUDDHASOTHORN HOSPITAL: AN AMBISPECTIVE OBSERVATIONAL COHORT STUDY

Journal of Southeast Asian Medical Research

Thailand-affiliated authors
Sirinapa Saneemanomai · Phatchapong Rurgring · Thinnapat Ninthasuk · Juthatip Rooyoo · Jidaporn Burenoi · Neera Krasaesoontorn · Benjawan Saengluan · Nunnaphat Khantiviriyapanich · Kanokporne Nakboon
Institutions
Rajabhat Rajanagarindra University · Thammasat University Hospital
77IMPACT SIGNAL
Clinical Medicine

Metabolic and Inflammatory Risk Stratification in Resected Cholangiocarcinoma: A Retrospective Exploratory Analysis

Medical Sciences

Thailand-affiliated authors
Piya Prajumwongs · Attapol Titapun · Vasin Thanasukarn · Apiwat Jareanrat · Natcha Khuntikeo · Nisana Namwat · Poramate Klanrit · Arporn Wangwiwatsin · Jarin Chindaprasirt · Prakasit Sa-Ngiamwibool · Nattha Muangritdech · Sittiruk Roytrakul · Watcharin Loilome
Institutions
Khon Kaen University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
77IMPACT SIGNAL
Clinical Medicine

Soluble C-type lectin LvLectin1 mediates recognition and agglutination of Ecytonucleospora hepatopenaei spores in Pacific white shrimp Litopenaeus vannamei

Aquaculture Reports

Thailand-affiliated authors
Warumporn Yingsunthonwattana · Kanokporn Bunyanam · Wisarut Junprung · Prakob Saman · Anchalee Tassanakajon
Institutions
Chulalongkorn University · Charoenkrung Pracharak Hospital
77IMPACT SIGNAL
Clinical Medicine

Three Decades of Outcomes in Pediatric Inborn Errors of Immunity in a Middle-Income Setting: Survival by IUIS Class and the Role of HSCT

Journal of Clinical Immunology

Thailand-affiliated authors
Chanunchida Watcharaporn · Usanarat Anurathapan · Suradej Hongeng · Samart Pakakasama · Wasu Kamchaisatian · Watcharoot Kanchongkittiphon · Wiparat Manuyakorn
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

Cooking-Induced Molecular Transformations in Foods: Matrix-Dependent Effects on Bioaccessibility, Metabolism, and Health

Food Reviews International

Thailand-affiliated authors
Muhammad Waqar
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

A rapid hybridization-free LAMP–LFB assay for the clinical detection of Neisseria gonorrhoeae in urine specimens

Scientific Reports

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Rossaphorn Kittiyaowamarn · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Ministry of Public Health
77IMPACT SIGNAL
Clinical Medicine

Effects of Ramadan Fasting on Intradialytic Hypoglycemia and Clinical Outcomes in Patients with Diabetes on Maintenance Hemodialysis: A Multicenter Prospective Cohort Study in Southern Thailand

Medical Sciences

Thailand-affiliated authors
Jayanton Patumanond · Moragot Chatatikun · Atthaphong Phongphithakchai
Institutions
Naresuan University · Walailak University · Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Diagnostic Performance of Six Tests for Helicobacter pylori Infection in Peptic Ulcer Bleeding: A Prospective Head-to-Head Comparison

Clinical and Translational Gastroenterology

Thailand-affiliated authors
Tanawat Geeratragool · Thanapat Atthakitmongkol · Supathep Tansirichaiya · Pubet Weeranawin · Somchai Leelakusolvong · Monthira Maneerattanaporn
Institutions
Siriraj Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link