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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Restoring Culturally Essential Floor-Sitting in Transfemoral Prosthesis Users: A Six-Week Pilot Randomized Within-Subject Trial

A pilot randomised within-subject trial in 14 unilateral transfemoral prosthesis users compared a low-profile, femoral-adducted Asian Transfemoral Socket with each participant's usual socket after six weeks of ATS use. Twelve participants attained cross-legged sitting and six additional participants attained side-sitting with ATS, alongside comfort and quality-of-life signals. Six-minute walking distance, four-square-step balance and daily steps did not differ significantly; the small sample could not exclude clinically important harm.

Thai researchersNatthawan Sutthison · Nang Myat Myat Moe · Yasmin Nutchamlong · Marisa Amattayakul · Mathurin Rairat · Woratee Dacharux · Kazuhiko Sasaki
Clinical Medicine89IMPACT SIGNAL
Global potential

Effects of a Home-Based Fall Prevention Program in Older Lower Limb Prosthesis Users: A Randomized Controlled Trial

A randomised controlled trial assigned 44 older lower-limb prosthesis users to usual care or education plus 16 home exercises three times weekly for eight weeks; 41 completed follow-up. Change in Timed Up and Go did not differ between groups, nor did static balance or balance confidence. No falls were reported during the study, but the sample and follow-up were too small to establish fall prevention or definitive lack of benefit. The null finding applies to this relatively high-mobility study population.

Thai researchersPrawina Sakulkosol · Pieter U Dijkstra · Kazuhiko Sasaki · Jutamanee Poonsiri
Genomic Public Health and Thalassaemia88IMPACT SIGNAL
Regional policy evidence synthesis

Thalassaemia prevention in Asia: progress, challenges, and future directions

This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured approaches, combining public awareness, carrier screening, genetic counselling, and prenatal diagnosis. Measurable success was clearest in Singapore and to a more limited extent Thailand. Many countries still face fragmented services, weak national coordination, workforce shortages, insufficient epidemiological data, and financial, technological, cultural, and social barriers. This is a regional health-system synthesis, not a comparative policy trial.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Vaccination Behaviour and Public Health89IMPACT SIGNAL
Observational cross-sectional evidence

Hepatitis B Vaccination Intention and Influencing Factors among College Students in Huanggang, Hubei, China: A Protection Motivation Theory-Based Cross-Sectional Study

This Protection Motivation Theory cross-sectional study surveyed 1,130 students aged 18–26 at three universities in Huanggang, Hubei, China, during April–May 2025. The authors dichotomized a 1–10 intention item into low scores of 1–6 and high scores of 7–10; 58.9% were in the high-intention group. In adjusted analysis, hepatitis B knowledge, vaccine knowledge, preventive behaviour, perceived severity, self-efficacy, and response efficacy were associated with higher odds of high intention, while perceived response cost was associated with lower odds. The findings identify intervention targets but do not show that changing them raises actual vaccination uptake.

Thai researchersCong Zhang · Phatcha Hirunwatthanakul · Nachalida Yukalang
Thalassaemia Epidemiology and Public Health Systems88IMPACT SIGNAL
Regional epidemiological synthesis

The Epidemiology of Thalassaemia Syndromes in Southeast Asia

This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and produce phenotypes ranging from asymptomatic carriage to lifelong transfusion dependence. Although a small set of mutations often dominates within each country, the regional spectrum is complex and population data remain incomplete. The paper highlights blood shortages, consanguinity in some settings, gender inequities, migration, and low awareness, and recommends national registries, premarital or prenatal screening, coordinated blood systems, and culturally sensitive education.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Sustainable Livestock and Agriculture89IMPACT SIGNAL
Animal-trial evidence with modeled environmental outcomes

Crude-Glycerin Leucaena Pellets Improve Goat Feed Efficiency, but Methane Reduction Is Modeled

Thai researchers tested Leucaena leucocephala pellets containing 0–15% crude glycerin in 32 male Boer × Thai native goats for 90 days. Intake fell slightly, but gain-to-feed ratio, fermentation indicators, and modeled economics improved. Methane and greenhouse-gas reductions were estimated from a stoichiometric model rather than direct emissions measurements.

Thai researchersNirandorn Nakdaeng · Sirirat Buaphan · Kanok Chaovapasee
Electric Mobility and Energy Infrastructure85IMPACT SIGNAL
Techno-economic case-study scenario analysis

Techno-Economic Assessment of EV Charging Infrastructure in Residential Buildings in Nonthaburi, Thailand

This Nonthaburi residential-building case study compared two 60-kW DC chargers, one 60-kW DC plus two 22-kW AC chargers, and four 22-kW AC chargers. Assumptions included a seven-year project, 5.5% discount rate, mean selling price of THB7.25/kWh, service time of 4, 6, or 8 hours per day, and electricity costs of THB4.50, 4.73, or 4.95/kWh, giving 27 scenarios. All three portfolios were financially feasible under the specified conditions. Two DC chargers gave the strongest return at eight hours per day and THB4.50/kWh, while four AC chargers better fit long parking durations and lower capital and maintenance costs.

Thai researchersChatchaphon Ketviriyakit · Pasura Aungkulanon · Lakkana Ruekkasaem
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Development and validation of a prognostic gene expression model for second primary malignancy in head and neck squamous cell carcinoma

Scientific Reports

Thailand-affiliated authors
Rungsinee Suksakulchai · Nutchavadee Vorasan · Lalida Arsa · Artit Jinawath · Warut Pongsapich · Tauangtham Anekpuritanang · Somkiat Sunpaweravong · Nuttapong Ngamphaiboon · Bhoom Suktitipat · Natini Jinawath
Institutions
Mahidol University · Ramathibodi Hospital · Siriraj Hospital · Prince of Songkla University · Ramathibodi Chakri Naruebodindra Hospital
77IMPACT SIGNAL
Clinical Medicine

Prediction models for early-onset atopic dermatitis in infancy: a prospective cohort study

Allergy Asthma and Clinical Immunology

Thailand-affiliated authors
Eakchalerm Eakpanit · Kamolwish Laoprasopwattan · Pasuree Sangsupawanich · Nattaporn Tassanakijpanich · Kemmapon Chumchuen · Vanlaya Koosakulchai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and Application of a Dual-Fluorescent Reporter Assay for Feline Infectious Peritonitis Virus RNA-Dependent RNA Polymerase Inhibitor Screening

International Journal of Molecular Sciences

Thailand-affiliated authors
Ploypailin Semkum · Varanya Lueangaramkul · Supichaya Jiwattanasap · Natjira Mana · Nantawan Phecharat · Porntippa Lekcharoensuk · Sirin Theerawatanasirikul
Institutions
Kasetsart University
77IMPACT SIGNAL
Environmental Engineering

Water Footprint of Local Herbs in Thailand Using the Water Footprint Network Methodology

Nature Environment and Pollution Technology

Thailand-affiliated authors
Harnpon Phungrassami · Phairat Usubharatana
Institutions
Thammasat University
77IMPACT SIGNAL
Clinical Medicine

The Citrus Flavonoid Naringin Confers Neuroprotection Against Cerebral Ischemia by Enhancing Endogenous Antioxidant Capacity and Suppressing Neuroinflammation

Foods

Thailand-affiliated authors
Ratchaniporn Kongsui · Nut Palachai · Araya Supawat · Sitthisak Thongrong · Jinatta Jittiwat
Institutions
University of Phayao · Mahasarakham University
77IMPACT SIGNAL
Fundamental Science

The Gravitational-wave Optical Transient Observer (GOTO) Fast Analysis and Spectroscopy of Transients (FAST) Surveys

Monthly Notices of the Royal Astronomical Society

Thailand-affiliated authors
U Sawangwit · K Noysena
Institutions
National Astronomical Research Institute of Thailand
77IMPACT SIGNAL
Clinical Medicine

Postpartum fever in sows housed in a temporary-confinement farrowing system under tropical conditions: risk factors and associations with feed intake, vaginal discharge, colostrum production, and hematological profiles

Porcine Health Management

Thailand-affiliated authors
Natnicha Thamma · Phatcharasri Dusadipong · Witchayanan Chakkrathon · Sunarin Robkob · Awatsada Malila · Tip-Apa Akkhaphan · Preechaphon Taechamaeteekul · Padet Tummaruk
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Validated QuEChERS–HPLC–UV Method for Quantification of Cannabidiol in Pharmaceutical Nanoformulations

ChemPlusChem

Thailand-affiliated authors
Pimpisa Chaobon · Phichaporn Bunwatcharaphansakun · Gehsirinnad Supattanachote · Katawut Namdee · Thitaphat Ngernsutivorakul
Institutions
Kasetsart University · National Nanotechnology Center · Ministry of Higher Education, Science, Research and Innovation
77IMPACT SIGNAL
Global Public Health

Immunogenicity and safety of high-dose versus double-dose quadrivalent inactivated influenza vaccine in adult kidney transplant recipients: a randomized controlled trial (2023)

The Lancet Regional Health - Southeast Asia

Thailand-affiliated authors
Thanachote Arayanumas · Kobporn Boonnak · Surasak Kantachuvesiri · Sarinya Boongird · Sasisopin Kiertiburanakul · Jackrapong Bruminhent
Institutions
Mahidol University · Ramathibodi Hospital · Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Immunomodulatory Potential of KSTM in Activating Natural Killer Cells for Cancer Cell Elimination

Pharmaceuticals

Thailand-affiliated authors
Tanyarat Pianmak · Aussara Panya · Natthanich Boonsatit · Lueacha Tabtimmai · Kiattawee Choowongkomon
Institutions
Kasetsart University · Chiang Mai University · King Mongkut's University of Technology North Bangkok
77IMPACT SIGNAL
Clinical Medicine

Clinical Characteristics, Antimicrobial Susceptibility, Treatment, and Outcomes of Achromobacter Bacteremia: A 20-Year Retrospective Cohort Study

Antibiotics

Thailand-affiliated authors
Tawin Khaimook · Pisud Siripaitoon · Sarunyou Chusri · Narongdet Kositpantawong · Siripen Kanchanasuwan · Sorawit Chittrakarn · Nattapat Sangkakul · Nonthanat Tongsengkee
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Clinical characteristics and species distribution of Mycobacterium fortuitum complex isolates

BMC Microbiology

Thailand-affiliated authors
Yonita Yuliani · Kanphai Wongjarit · Prangwalai Chanchaem · Kasidis Phongkhun · Suthida Visedthorn · Suthidee Petsong · Pornchai Kaewsapsak · Sunchai Payungporn · Suwatchareeporn Rotcheewaphan
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Environmental Correlates of Opisthorchis viverrini Infection-Free Zones: A Comparative Machine Learning Approach Using Satellite-Derived Indices

Symmetry

Thailand-affiliated authors
Nutchanat Buasri · Patiwat Littidej · Benjamabhorn Pumhirunroj
Institutions
Mahasarakham University · Sakon Nakhon Rajabhat University
77IMPACT SIGNAL
Clinical Medicine

Prognostic significance of post-treatment total lymphocyte count in locally advanced cervical cancer after definitive chemoradiotherapy

BMC Women s Health

Thailand-affiliated authors
Chutisa Phuvaruttanakul · Kittinun Leetanaporn · Rakchai Buhachat · Ingporn Jiamset · Ekasak Thiangphak
Institutions
Prince of Songkla University · Songklanagarind Hospital
77IMPACT SIGNAL
Clinical Medicine

Factors associated with extravasation severity in Thai patients receiving noncytotoxic intravenous infusions: An observational study

Belitung Nursing Journal

Thailand-affiliated authors
Thitiporn Pathomjaruwat · Borwarnluck Thongthawee · Padcha Pongcharoen · Charturong Tantibundhit
Institutions
Thammasat University · Rangsit University
77IMPACT SIGNAL
Clinical Medicine

FACTORS ASSOCIATED WITH HOSPITAL ARRIVAL TIME IN ISCHEMIC STROKE PATIENTS AT BUDDHASOTHORN HOSPITAL: AN AMBISPECTIVE OBSERVATIONAL COHORT STUDY

Journal of Southeast Asian Medical Research

Thailand-affiliated authors
Sirinapa Saneemanomai · Phatchapong Rurgring · Thinnapat Ninthasuk · Juthatip Rooyoo · Jidaporn Burenoi · Neera Krasaesoontorn · Benjawan Saengluan · Nunnaphat Khantiviriyapanich · Kanokporne Nakboon
Institutions
Rajabhat Rajanagarindra University · Thammasat University Hospital
77IMPACT SIGNAL
Clinical Medicine

Metabolic and Inflammatory Risk Stratification in Resected Cholangiocarcinoma: A Retrospective Exploratory Analysis

Medical Sciences

Thailand-affiliated authors
Piya Prajumwongs · Attapol Titapun · Vasin Thanasukarn · Apiwat Jareanrat · Natcha Khuntikeo · Nisana Namwat · Poramate Klanrit · Arporn Wangwiwatsin · Jarin Chindaprasirt · Prakasit Sa-Ngiamwibool · Nattha Muangritdech · Sittiruk Roytrakul · Watcharin Loilome
Institutions
Khon Kaen University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
77IMPACT SIGNAL
Clinical Medicine

Soluble C-type lectin LvLectin1 mediates recognition and agglutination of Ecytonucleospora hepatopenaei spores in Pacific white shrimp Litopenaeus vannamei

Aquaculture Reports

Thailand-affiliated authors
Warumporn Yingsunthonwattana · Kanokporn Bunyanam · Wisarut Junprung · Prakob Saman · Anchalee Tassanakajon
Institutions
Chulalongkorn University · Charoenkrung Pracharak Hospital
77IMPACT SIGNAL
Clinical Medicine

Three Decades of Outcomes in Pediatric Inborn Errors of Immunity in a Middle-Income Setting: Survival by IUIS Class and the Role of HSCT

Journal of Clinical Immunology

Thailand-affiliated authors
Chanunchida Watcharaporn · Usanarat Anurathapan · Suradej Hongeng · Samart Pakakasama · Wasu Kamchaisatian · Watcharoot Kanchongkittiphon · Wiparat Manuyakorn
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

Cooking-Induced Molecular Transformations in Foods: Matrix-Dependent Effects on Bioaccessibility, Metabolism, and Health

Food Reviews International

Thailand-affiliated authors
Muhammad Waqar
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

A rapid hybridization-free LAMP–LFB assay for the clinical detection of Neisseria gonorrhoeae in urine specimens

Scientific Reports

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Rossaphorn Kittiyaowamarn · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Ministry of Public Health
77IMPACT SIGNAL
Clinical Medicine

Effects of Ramadan Fasting on Intradialytic Hypoglycemia and Clinical Outcomes in Patients with Diabetes on Maintenance Hemodialysis: A Multicenter Prospective Cohort Study in Southern Thailand

Medical Sciences

Thailand-affiliated authors
Jayanton Patumanond · Moragot Chatatikun · Atthaphong Phongphithakchai
Institutions
Naresuan University · Walailak University · Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Diagnostic Performance of Six Tests for Helicobacter pylori Infection in Peptic Ulcer Bleeding: A Prospective Head-to-Head Comparison

Clinical and Translational Gastroenterology

Thailand-affiliated authors
Tanawat Geeratragool · Thanapat Atthakitmongkol · Supathep Tansirichaiya · Pubet Weeranawin · Somchai Leelakusolvong · Monthira Maneerattanaporn
Institutions
Siriraj Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link