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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
Rational Prescribing and Medication Safety74IMPACT SIGNAL
Evidence of global relevance

Assessment of Inappropriate Omeprazole Prescribing, Associated Factors and Financial Impact in the Outpatient Department of a General Hospital in Thailand

A review of 347 outpatient prescriptions for 229 patients from January-June 2025 at one Thai general hospital classified 58.2% of omeprazole prescriptions as potentially inappropriate. Of these, 75.2% lacked an appropriate indication, followed by inappropriate duration.

Thai researchersSaranporn Srithonrat · Chayanat Pongsathabordee · Satawat Kulworahathai · Chidawan Prapat · Aticha Jamratkittiwan · Nichakan Jitakson · Taniya Paiboonvong
Endocrine Emergency Medicine74IMPACT SIGNAL
Evidence of global relevance

Prognostic factors and prognostic risk score of 30-day all-cause mortality in thyroid storm

A retrospective cohort of 115 thyroid-storm patients at a Thai tertiary center had 13% 30-day mortality. An eight-point score using male sex, hypertension, SOFA at least 2, and GCS at most 10 achieved apparent AUC 0.81 and bootstrap-corrected AUC 0.79.

Thai researchersPakpoom Chantrapitak · Worapaka Manosroi · Sittikul Thipbumrung · Pichitchai Atthakomol
Companion-Animal AMR and One Health74IMPACT SIGNAL
Evidence of global relevance

Genomic Characterization, Antimicrobial Resistance Profiles, and tetA Nucleotide Substitutions of Escherichia coli Isolated from Healthy Dogs in Thailand

Fecal samples from 200 healthy dogs at 50 clinics in Chiang Mai and Nakhon Si Thammarat during January-March 2026 yielded 66 E. coli isolates. Resistance reached 100% for ampicillin, 84.85% for piperacillin, 60.61% for ceftriaxone, 56.06% for tetracycline, and 47% multidrug resistance.

Thai researchersRavisa Warin · Naparat Suttidate · Wanna Suriyasathaporn · Witaya Suriyasathaporn · Ratchadaporn Boripun
Microalgae and Energy Harvesting74IMPACT SIGNAL
Evidence of global relevance

Immobilized microalgae-driven triboelectric nanogenerators for sustainable bioelectricity production

Thai researchers immobilized living Chlorella vulgaris TISTR 8580 at different densities on aluminum electrodes as a triboelectric layer for solid-solid and solid-liquid interactions, reporting peak output of 110 V and 330 nA.

Thai researchersChalampol Janpum · Tanakit Komkhum · Naratip Vittayakorn · Kamon Thinsurat · Chawalit Ngamcharussrivichai · Pichaya In-na
Alternative Proteins, Drying, and Flavor73IMPACT SIGNAL
Evidence of global relevance

Drying-Induced Structural and Oxidative Transformations in Sustainable Proteins: Impact on Physicochemical Properties and Flavor-Binding Functionality

This review proposes a structure-process-function framework explaining how hot-air, heat-pump, microwave, and freeze-drying differently unfold, aggregate, and oxidize plant and marine proteins, changing how volatile flavors are bound, retained, and released.

Thai researchersYoon Hlaine Barani · Passakorn Kingwascharapong · Saroat Rawdkuen
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Diagnostic accuracy of a clinical score with a rapid diagnostic test for enteric fever in Nepal, Bangladesh and Cambodia

BMC Infectious Diseases

Thailand-affiliated authors
Nicholas P.J. Day · Arjen Dondorp
Institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Shared and Distinct T-Cell Receptor Characteristics of CD4+ and CD8+ Drug-Specific T-Cells In Vitro Generated from Healthy Donors and Hypersensitive Patients

Chemical Research in Toxicology

Thailand-affiliated authors
Kanoot Jaruthamsophon · Jirawat Pratoomwun · Antida Sangiemchoey · Araya Yeunyongviwat · Kanitpong Phabphal · Chonlaphat Sukasem
Institutions
Prince of Songkla University · Huachiew Chalermprakiet University · Mahidol University · Ramathibodi Hospital · Burapha University
77IMPACT SIGNAL
Clinical Medicine

Localization of feline gammaherpesvirus 1 in lymphoid tissues and pulmonary fibrotic lesions of naturally infected cats

Veterinary Pathology

Thailand-affiliated authors
Chutchai Piewbang · Magdalena Novia Devina Putri · Aisyah Nikmatuz Zahro · Panitnan Punyathi · Sitthichok Lacharoje · Somporn Techangamsuwan
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Clinical features associated with autism spectrum disorder diagnosed before 30 months of age: evidence from tertiary care hospitals in Thailand

International Journal of Developmental Disabilities

Thailand-affiliated authors
Anya Laopongsit · Nontiya Homkham · Pimwarat Srikummoon · Kamonrut Koobubpha · Patrinee Traisathit
Institutions
Chiang Rai Rajabhat University · Thammasat University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Rapid Gel-Based Recombinase Polymerase Amplification Assay for Detection and Sequence Confirmation of Ehrlichia canis

Animals

Thailand-affiliated authors
Peeravit Sumpavong · Kitjawan Khumtub · Krittanut Kanittakul · Sarawan Kaewmongkol · Gunn Kaewmongkol
Institutions
Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Synchronous B-lymphoblastic leukemia/lymphoma and subcutaneous panniculitis-like T-cell lymphoma in an 11-year-old pediatric patient

BMC Pediatrics

Thailand-affiliated authors
Phuphinyo Limchantra · Jirat Temsangsukmanee · Suradej Hongeng · Kran Suknuntha
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

A Decade of Croup Management: Guideline Adherence, Practice Variation, and Opportunities for Improvement

Children

Thailand-affiliated authors
Jirattikarn Jirawong · Wanaporn Anuntaseree · Kanokpan Ruangnapa · Kantara Saelim · Pharsai Prasertsan
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Cloud-Based Deep Learning for Multi-Class Dermatological Screening: An Empirical Study Using Pretrained CNNs

Sci

Thailand-affiliated authors
Theetach Rabablert · Amonnat Kaewnok · Chitnarong Sirisathitkul · Yaowarat Sirisathitkul
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

Molecular Characteristics and Factors Associated with Antimicrobial Resistance in Campylobacter Isolates from Small-Scale Chicken Farms in Southern Thailand

Antibiotics

Thailand-affiliated authors
Nguyễn Thị Mỹ Nhân · Phitchayapak Wintachai · Thotsapol Thomrongsuwannakij
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

PARP inhibition induces a redox-dependent dormant reservoir vulnerable to disulfiram in high-grade serous ovarian cancer

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Sutthipun Suriya · Supawan Jamnongsong · Chanettee Jamyuang · Suwanit Therasakvichya · Somponnat Sampattavanich
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Digital Health

Electroencephalography-Based Emotion Recognition Using Auditory Stimulation for Affective Brain–Computer Interfaces

Sensors

Thailand-affiliated authors
Charoenporn Bouyam · Nannaphat Siribunyaphat · Yunyong Punsawad
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

KK12, a novel anticancer peptide, induces apoptosis in human lung cancer A549 cells

Scientific Reports

Thailand-affiliated authors
Jantana Yahuafai · Prayumat Onsrisawat · Ratasark Summart · Mariena Ketudat-Cairns · Thippawan Pimchan · Jirawat Yongsawatdigul · Natteewan Udomsil
Institutions
National Cancer Institute of Thailand · Kanchanaburi Rajabhat University · Mahidol University · Suranaree University of Technology
77IMPACT SIGNAL
Clinical Medicine

Limitations of NEWS2 for predicting 48-hour emergency department revisits: a real-world retrospective cohort study

International Journal of Emergency Medicine

Thailand-affiliated authors
Sarunpakorn Permpatdechakul · Theerapon Tangsuwanaruk · Borwon Wittayachamnankul · Pavita Laohakul · Chanon Changratanakorn · Boriboon Chenthanakij
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Efficacy of mucoadhesive nanoemulsion-based immersion vaccine against Streptococcus agalactiae and Edwardsiella tarda infections in Nile tilapia (Oreochromis niloticus)

Aquaculture Reports

Thailand-affiliated authors
Benchawan Kumwan · Pakapon Meachasompop · Yosapon Adisornprasert · Jitraporn Phaksopa · Wararut Buncharoen · Patcharapong Thangsunan · Pattanapong Thangsunan · Prapansak Srisapoome · Channarong Rodkhum · Natthapong Paankhao · Anurak Uchuwittayakul
Institutions
Kasetsart University · Chiang Mai University · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Dietary Application of Synergistically Degraded Low-Molecular-Weight Chitosan to Promote Health and Antioxidant Responses in Pacific White Shrimp (Litopenaeus vannamei)

Antioxidants

Thailand-affiliated authors
Natthapong Paankhao · Wararut Buncharoen · Benchawan Kumwan · Pakapon Meachasompop · Yosapon Adisornprasert · Chonlatat Rajitdumrong · Pimrawee Chaemlek · Prapansak Srisapoome · Passakorn Kingwascharapong · Anurak Uchuwittayakul
Institutions
Kasetsart University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Purifying Selection and Interspecific Differentiation at the Myf5 Locus Inform Hybrid Identification and Genetic Management of Thai Clariid Resources

Genes

Thailand-affiliated authors
Phonemany Thammachak · Ton Huu Duc Nguyen · Rinrapat Nitipatpornpanya · Anh Huynh Luu · Edem Uduak Linus · Thitipong Panthum · Kednapat Sriphairoj · Sittichai Hatachote · Satid Chatchaiphan · Chaiwut Grudpan · Jarungjit Grudpan · S. Kiriratnikom · Jiraboon Prasanpan · Orathai Sawatdichaikul · Worapong Singchat · Kornsorn Srikulnath
Institutions
Kasetsart University · Sakon Nakhon Rajabhat University · Ubon Ratchathani University · Thaksin University · Kalasin University
77IMPACT SIGNAL
Clinical Medicine

Long-acting reversible contraceptive use in postpartum and postabortion adolescents: initiation, predictors, and continuation outcomes

Reproductive Health

Thailand-affiliated authors
Paparnin Sangvornrungsie · Nalinee Panichyawat · Thanyarat Wongwananuruk · Nichamon Parkpinyo · Julaporn Pooliam · Marisa Vongsiri · Jaratporn Inthawong
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Proteomic Analysis of Urinary Extracellular Vesicles Reveals Estrogen/Progesterone Status-Associated Biomarkers of Breast Cancer Patients: Potential Roles in Diagnosis and Prognosis

Journal of Health Science and Medical Research

Thailand-affiliated authors
Rassanee Bissanum · Nilobon Jeanmard · Hutcha Sriplung · Sawanya Charoenlappanit · Sittiruk Roytrakul · Raphatphorn Navakanitworakul
Institutions
Prince of Songkla University · National Science and Technology Development Agency
77IMPACT SIGNAL
Clinical Medicine

New Host and Geographic Records of Epifoliar Fungi on Cinnamomum loureiroi from Thailand

Phytotaxa

Thailand-affiliated authors
Asieh Vasighzadeh · Alireza Armand · Ruvishika S. Jayawardena · Kevin D. Hyde
Institutions
Mae Fah Luang University
77IMPACT SIGNAL
Clinical Medicine

Organization of the Digestive Tract and Localization of Protein Fibre in Electrophorus sp. (Gymnotiformes: Gymnotidae)

Acta Zoologica

Thailand-affiliated authors
Sinlapachai Senarat · Narit Thaochan · Kitiya Kongthong · Peerapon Sornying · Piyakorn Boonyoung
Institutions
Prince of Songkla University · Naresuan University
77IMPACT SIGNAL
Clinical Medicine

Multi-Targeted Neuroprotection by Areca catechu Against Cisplatin-Induced Neurotoxicity: Cellular, Caenorhabditis elegans, and Metabolomic Evidence

International Journal of Molecular Sciences

Thailand-affiliated authors
Kishoree Krishna Kumaree · Clerance Su Yee Cheong · Kanika Verma · Kartina Nadyani · Nureesun Mahamud · Pornpimol Mahamad · Tewin Tencomnao · Anchalee Prasansuklab · James Michael Brimson
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Investigation of Cytokine Profiles, the Expression of Genes Involved in Somatic Hypermutation and Peripheral Tolerance, and Their Correlation with Autoantibody Levels in Northern-Thai Immunodeficient Patients Carrying Anti-Interferon-γ Autoantibodies

International Journal of Molecular Sciences

Thailand-affiliated authors
Kritsadee Rattanathammethee · Kriangkrai Chawansuntati · Nongkran Lumjuan · Nattaya Nusartsang · Romanee Chaiwarith · Jutarat Praparattanapan · Khuanchai Supparatpinyo · Jiraprapa Wipasa
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Real-world evidence on off-label underdosing of direct oral anticoagulants in Asian patients with atrial fibrillation: prescribing patterns, determinants, and outcomes

Future Science OA

Thailand-affiliated authors
Supisara Pholprasittito · Supharat Wattanasombat · Natrawee Bureekam
Institutions
Lampang Hospital · ChiangRai Prachanukroh Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link