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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Restoring Culturally Essential Floor-Sitting in Transfemoral Prosthesis Users: A Six-Week Pilot Randomized Within-Subject Trial

A pilot randomised within-subject trial in 14 unilateral transfemoral prosthesis users compared a low-profile, femoral-adducted Asian Transfemoral Socket with each participant's usual socket after six weeks of ATS use. Twelve participants attained cross-legged sitting and six additional participants attained side-sitting with ATS, alongside comfort and quality-of-life signals. Six-minute walking distance, four-square-step balance and daily steps did not differ significantly; the small sample could not exclude clinically important harm.

Thai researchersNatthawan Sutthison · Nang Myat Myat Moe · Yasmin Nutchamlong · Marisa Amattayakul · Mathurin Rairat · Woratee Dacharux · Kazuhiko Sasaki
Clinical Medicine89IMPACT SIGNAL
Global potential

Effects of a Home-Based Fall Prevention Program in Older Lower Limb Prosthesis Users: A Randomized Controlled Trial

A randomised controlled trial assigned 44 older lower-limb prosthesis users to usual care or education plus 16 home exercises three times weekly for eight weeks; 41 completed follow-up. Change in Timed Up and Go did not differ between groups, nor did static balance or balance confidence. No falls were reported during the study, but the sample and follow-up were too small to establish fall prevention or definitive lack of benefit. The null finding applies to this relatively high-mobility study population.

Thai researchersPrawina Sakulkosol · Pieter U Dijkstra · Kazuhiko Sasaki · Jutamanee Poonsiri
Genomic Public Health and Thalassaemia88IMPACT SIGNAL
Regional policy evidence synthesis

Thalassaemia prevention in Asia: progress, challenges, and future directions

This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured approaches, combining public awareness, carrier screening, genetic counselling, and prenatal diagnosis. Measurable success was clearest in Singapore and to a more limited extent Thailand. Many countries still face fragmented services, weak national coordination, workforce shortages, insufficient epidemiological data, and financial, technological, cultural, and social barriers. This is a regional health-system synthesis, not a comparative policy trial.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Vaccination Behaviour and Public Health89IMPACT SIGNAL
Observational cross-sectional evidence

Hepatitis B Vaccination Intention and Influencing Factors among College Students in Huanggang, Hubei, China: A Protection Motivation Theory-Based Cross-Sectional Study

This Protection Motivation Theory cross-sectional study surveyed 1,130 students aged 18–26 at three universities in Huanggang, Hubei, China, during April–May 2025. The authors dichotomized a 1–10 intention item into low scores of 1–6 and high scores of 7–10; 58.9% were in the high-intention group. In adjusted analysis, hepatitis B knowledge, vaccine knowledge, preventive behaviour, perceived severity, self-efficacy, and response efficacy were associated with higher odds of high intention, while perceived response cost was associated with lower odds. The findings identify intervention targets but do not show that changing them raises actual vaccination uptake.

Thai researchersCong Zhang · Phatcha Hirunwatthanakul · Nachalida Yukalang
Thalassaemia Epidemiology and Public Health Systems88IMPACT SIGNAL
Regional epidemiological synthesis

The Epidemiology of Thalassaemia Syndromes in Southeast Asia

This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and produce phenotypes ranging from asymptomatic carriage to lifelong transfusion dependence. Although a small set of mutations often dominates within each country, the regional spectrum is complex and population data remain incomplete. The paper highlights blood shortages, consanguinity in some settings, gender inequities, migration, and low awareness, and recommends national registries, premarital or prenatal screening, coordinated blood systems, and culturally sensitive education.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Sustainable Livestock and Agriculture89IMPACT SIGNAL
Animal-trial evidence with modeled environmental outcomes

Crude-Glycerin Leucaena Pellets Improve Goat Feed Efficiency, but Methane Reduction Is Modeled

Thai researchers tested Leucaena leucocephala pellets containing 0–15% crude glycerin in 32 male Boer × Thai native goats for 90 days. Intake fell slightly, but gain-to-feed ratio, fermentation indicators, and modeled economics improved. Methane and greenhouse-gas reductions were estimated from a stoichiometric model rather than direct emissions measurements.

Thai researchersNirandorn Nakdaeng · Sirirat Buaphan · Kanok Chaovapasee
Electric Mobility and Energy Infrastructure85IMPACT SIGNAL
Techno-economic case-study scenario analysis

Techno-Economic Assessment of EV Charging Infrastructure in Residential Buildings in Nonthaburi, Thailand

This Nonthaburi residential-building case study compared two 60-kW DC chargers, one 60-kW DC plus two 22-kW AC chargers, and four 22-kW AC chargers. Assumptions included a seven-year project, 5.5% discount rate, mean selling price of THB7.25/kWh, service time of 4, 6, or 8 hours per day, and electricity costs of THB4.50, 4.73, or 4.95/kWh, giving 27 scenarios. All three portfolios were financially feasible under the specified conditions. Two DC chargers gave the strongest return at eight hours per day and THB4.50/kWh, while four AC chargers better fit long parking durations and lower capital and maintenance costs.

Thai researchersChatchaphon Ketviriyakit · Pasura Aungkulanon · Lakkana Ruekkasaem
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Elevated lipoprotein(a), trimethylamine n-oxide, and gut dysbiosis are associated with subclinical coronary atherosclerosis independent of metabolic dysfunction-associated steatotic liver disease

Scientific Reports

Thailand-affiliated authors
Pairoj Chattranukulchai · Monravee Tumkosit · Pattida Kongsomboonchoke · Pinidphon Prombutara · Anchalee Avihingsanon · Isawan Petchlorlian · Kearkiat Praditpornsilpa · Pisit Tangkijvanich
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital · Thai Red Cross Society · HIV Netherlands Australia Thailand Research Collaboration
77IMPACT SIGNAL
Clinical Medicine

Potent Cross-SerotypeDengue Neutralization with LowADE by AG-Strand-Targeting Anti-EDIII Antibodies

ACS Omega

Thailand-affiliated authors
Napon Nilchan · Anunyaporn Phungsom · Mongkhonphan Tantiwatcharakunthon · Prasit Luangaram · Pattarakul Pakchotanon · Thaneeya Duangchinda · Romchat Kraivong · Tanapan Prommool · Chatchawan Srisawat · Chunya Puttikhunt
Institutions
National Science and Technology Development Agency · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Unexpected diversity of flower-associated Aureobasidium reveals sixteen novel species from northern Thailand

IMA Fungus

Thailand-affiliated authors
Chanokned Senwanna · Pratthana Kodchasee · Chirayut Kathongthung · Milan C. Samarakoon · Pannida Khunnamwong · Jaturong Kumla · Nakarin Suwannarach
Institutions
Chiang Mai University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Becker Muscular Dystrophy with Exon 27-43 Deletion: Clinical andGenetic Insights in a Pediatric Case: A Case Report

Medical Journal of Armed Police Force Nepal

Thailand-affiliated authors
Sri Ram K. C. · Bharat Chand · Drishti Poudel · Prakash Man Shah · Rajani Karki
Institutions
Police General Hospital
77IMPACT SIGNAL
Clinical Medicine

Intelligent Diagnosis of Periapical Pathologies in Dental Radiographs Using an Optimized Triple-Ensemble Deep Learning Framework with Real-World Clinical Validation

Intelligent Systems with Applications

Thailand-affiliated authors
Rapeepan Pitakaso · Kittipit Klanliang · Peerawat Luesak · Sarayut Gonwirat · Chutchai Kaewta · Prem Enkvetchakul · Chawis Boonmee
Institutions
Ubon Ratchathani University · Chiang Mai University · Rajamangala University of Technology Lanna · Kalasin University · Ubon Ratchathani Rajabhat University · Buriram Rajabhat University
77IMPACT SIGNAL
Clinical Medicine

Vitamin D and adverse pathologic features in patients undergoing radical prostatectomy in the contemporary magnetic resonance imaging‐guided management era

BJUI Compass

Thailand-affiliated authors
Sarita Chitjaroen · Kantima Jongjitaree · Varat Woranisarakul · Siros Jitpraphai · Tawatchai Taweemonkongsap · Sunai Leewansangtong · Sittiporn Srinualnad · Thitipat Hansomwong
Institutions
Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Can NEWS predict hospital mortality in patients who left the medical ICU? A retrospective cohort study in resource-limited setting

Annals of critical care

Thailand-affiliated authors
Seksan Chaisuksant · Watchara Boonsawat · Sittichai Khamsai · Kittisak Sawanyawisuth
Institutions
Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Acute erythroid leukaemia transformation in polycythaemia vera with leukemic involvement in liver and ascites

BMJ Case Reports

Thailand-affiliated authors
Allison Kaye Lombridas Pagarigan · Natcha Sumpansirikul · Ekapun Karoopongse · Sanya Sukpanichnant
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

SUSTAINED CLINICAL REMISSION AND LONG-TERM SAFETY OF MOLNUPIRAVIR AS FIRST-LINE THERAPY FOR EFFUSIVE FELINE INFECTIOUS PERITONITIS: A 40-WEEK RETROSPECTIVE STUDY

Veterinary and Animal Science

Thailand-affiliated authors
Thiti Surakitkoson · Phuttipan Channgam · Walasinee Sakcamduang · Jeerawat Soonthornsit · Rungrote Osathanon
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Complete mitochondrial genome characterization of the haemosporidian parasite Nycteria heischi in bats Megaderma spasma in Thailand

Current Research in Parasitology and Vector-Borne Diseases

Thailand-affiliated authors
Pattaranatcha Charnwichai · Juthathip Poofery · Dimas Novianto · Siwaporn Tuangpermsub · Thongchai Ngamprasertwong · Morakot Kaewthamasorn
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Accelerating Evidence-Based Practices in Acute Kidney Injury

Clinical Journal of the American Society of Nephrology

Thailand-affiliated authors
Nattachai Srisawat
Institutions
Chulalongkorn University · The Royal College Of Anesthesiologists Of Thailand
77IMPACT SIGNAL
Clinical Medicine

ALY688 confers cardioprotection through macrophage TGFβ-mediated Treg/Th17 dependent multi-organ responses

Pharmacological Research

Thailand-affiliated authors
Sasipat Teerawongsuwan · Ruttachuk Rungsiwiwut · Sivaporn Wannaiampikul
Institutions
Srinakharinwirot University
77IMPACT SIGNAL
Multidisciplinary

Innovative extraction technology and sustainable valorization of industrially-generated longan waste stream

Discover Food

Thailand-affiliated authors
Idris Kaida Zubairu · Noppol Leksawasdi · Sutee Wangtueai · Suphat Phongthai · Abubakar Ibrahim Garba · Yuthana Phimolsiripol
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Effects of a Tubtim Chumphae Rice Extract Facial Serum on Skin Biophysical Properties in Healthy Middle-Aged Adults: A Split-Face Controlled Clinical Trial

Cosmetics

Thailand-affiliated authors
Thapanee Roengrit · Thirapit Subongkot · Thanchanok Sirirak · Suwipa Intakhiao · Jatuporn Phoemsapthawee · Piyapong Prasertsri
Institutions
Suranaree University of Technology · Burapha University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Impact of bacterial infection on native liver survival in children with cirrhosis due to biliary atresia

Clinical and Experimental Pediatrics

Thailand-affiliated authors
Varissara Kaewchaivijit · Pornthep Tanpowpong · Songpon Getsuwan · Sophida Boonsathorn · Chatmanee Lertudomphonwanit · Suporn Treepongkaruna
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

Antimicrobial peptide LL-37 promotes proliferation of human bone marrow-derived mesenchymal stem cells

Scientific Reports

Thailand-affiliated authors
Putida Pinthonglor · Pareena Chotjumlong · Dumnoensun Pruksakorn · Jeerawan Klangjorhor · Patcharawadee Thongkumkoon · Worakanya Buranaphatthana · Sarawut Kumphune · Chayarop Supanchart
Institutions
Chiang Mai University
77IMPACT SIGNAL
Environmental Engineering

Development of Empirical Models for Estimating Daily Downward Longwave Radiation Using Meteorological Data in Thailand

Journal of Renewable Energy and Smart Grid Technology

Thailand-affiliated authors
Rungrat Wattan · Chutimon Phoemwong · Supawadee Nokphueng · S. Buntoung · K. Tohsing · Serm Janjai
Institutions
Silpakorn University · St Theresa International College
77IMPACT SIGNAL
Environmental Engineering

Assessment of meteorological drought in Thailand: Historical and future projections under CMIP6 climate change scenarios

Journal of Hydrology Regional Studies

Thailand-affiliated authors
Teerawat Ram-Indra · Nantawoot Inseeyong · Supattra Visessri
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

A new approach to improve outpatient departments to mitigate respiratory infectious diseases

Journal of Asian Architecture and Building Engineering

Thailand-affiliated authors
Jutamat Chotirat · Kantaphong Srimuang · Supuck Prugsiganont van der Hoeven
Institutions
Walailak University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Non-GMO surface display of VP28 on Pediococcus pentosaceus for oral protection against white spot syndrome virus in shrimp

Scientific Reports

Thailand-affiliated authors
Pinpunya Riangrungroj · Suparat Taengchaiyaphum · Somphop Boonpayung · Siwaporn Longyant · Dujduan Waraho-Zhmayev · Kallaya Sritunyalucksana · Ubolsree Leartsakulpanich
Institutions
National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology · Srinakharinwirot University · King Mongkut's University of Technology Thonburi
77IMPACT SIGNAL
Clinical Medicine

Papiliotrema anthoicola Kathongthung, Kodchasee, Senwanna, J. Kumla & N. Suwannar. 2026, sp. nov.

Open MIND

Thailand-affiliated authors
Chirayut Kathongthung · Pratthana Kodchasee · Saowaluck Singsalood · Chanokned Senwanna · Pannida Khunnamwong · Jaturong Kumla · Nakarin Suwannarach
Institutions
Chiang Mai University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Preparation of Quercetin-Loaded Lipid Nanoparticle-Embedded Hydrogels and Stability Studies

Molecules

Thailand-affiliated authors
Chatchapong Tangjidapichai · Sarin Tadtong · Chuda Chittasupho · Weerasak Samee
Institutions
Srinakharinwirot University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Depressive symptom profiles across pregnant, postpartum, and nonperipartum women: measurement invariance and differential item functioning analyses of 2005–2021 NHANES data

BMC Public Health

Thailand-affiliated authors
Manit Srisurapanont · Chawisa Suradom · Narong Maneeton · Awiruth Oon-arom · Benchalak Maneeton
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Subclinical thiamine deficiency in third-trimester pregnancy despite routine antenatal supplementation: a cross-sectional study in an urban setting, Bangkok, Thailand

BMC Pregnancy and Childbirth

Thailand-affiliated authors
Ajjima Thussachan · Itsara Jangjaroenphorn · Monnapa Chantrangkul · Apanchanid Thepouypon · Chattraya Ngamlerst · Natnicha Promyos · Kamparnart Kaewyai · Dennopporn Sudjai · Kriengsak Limkittikul · Thitiya Yakasaem · Salin Sirinam · Weerawan Hattasingh
Institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit · Rajavithi Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link