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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Health sciences70IMPACT SIGNAL
Tracked in the research database

Protocol for assessing anti-Siglec-9 antibody-mediated tumor phagocytosis by macrophages using pH-sensitive dyes and flow cytometry

The protocol standardises monocyte isolation, macrophage differentiation, K562 preparation and pH-sensitive flow cytometry to distinguish binding from internalisation. It improves mechanistic reproducibility but does not demonstrate patient efficacy or safety.

Thai researchersSaitong Muneekaew · Thunchanok Nuchphongsai · Pasut Sasithong · Kritayaporn Saiprayong · Kamonphan Rungrueang · Methichit Wattanapanitch
Health sciences70IMPACT SIGNAL
Tracked in the research database

Artificial intelligence for urodynamic studies: systematic review of methods, performance, and clinical applications

A PRISMA-guided review searches four databases and groups AI for urodynamics into parameter-, raw-signal- and image-based approaches. Small datasets, bias and limited external validation prevent a conclusion that these tools are deployment-ready.

Thai researchersApisith Saraluck · Jittima Manonai · Athasit Kijmanawat · Rujira Wattanayingcharoenchai
Health sciences70IMPACT SIGNAL
Tracked in the research database

Updated safety and efficacy of puxitatug samrotecan (Puxi-Sam, AZD8205) in patients (pts) with endometrial cancer (EC) or ovarian cancer (OC): Phase 1/2a BLUESTAR study.

This BLUESTAR conference update reports early safety and response signals for a B7-H4-directed antibody-drug conjugate in relapsed or metastatic endometrial and ovarian cancer. It is dose-development evidence, not comparative or survival proof.

Thai researchersThatthan Suksombooncharoen
Tectonics and Erosion71IMPACT SIGNAL
Global observational analysis

Global data suggest faults enhance erosion through rock damage extending up to about 100 kilometers

Fault-driven uplift is known, but this study asks whether damaged rock also erodes more efficiently. A global dataset of 1,744 cosmogenic beryllium-10 erosion rates showed elevated efficiency within about 15 km of faults, decaying to roughly 100 km. Reverse faults and faults longer than 140 km had the strongest effects. The range beyond fault cores suggests fracturing, seismic shaking or distributed deformation. Machine learning ranked fault proximity above precipitation and lithology, especially with a shaking metric.

Thai researchersB. Kuhasubpasin
Antimicrobial Resistance and Community Transmission70IMPACT SIGNAL
Prospective One Health cohort

Persistent high-density E. coli ST131 carriers may sustain household transmission

E. coli ST131 drives community multidrug-resistant extraintestinal infection. A prospective Singapore household cohort enrolled 17 prior ST131 and 17 other E. coli index patients plus coresidents, with serial stool from 135 people, six pets and environmental swabs from 34 households. Nine persistent high-density carriers had ST131 comprising 57.79% of E. coli isolates and median carriage of 86.35 days. Carrier and coresident isolates were a median two SNPs apart, and carriers had greater diversity, suggesting potential reservoir and source roles.

Thai researchersYin Mo
STI Treatment and New Antibiotics70IMPACT SIGNAL
Phase 3 non-inferiority evidence

Single-dose oral zoliflodacin was non-inferior to ceftriaxone plus azithromycin for urogenital gonorrhoea

A phase 3 open-label trial at 17 clinics in five countries including Thailand randomized people aged 12+ with suspected uncomplicated urogenital gonorrhoea 2:1 to single oral zoliflodacin 3 g (621) or IM ceftriaxone 500 mg plus oral azithromycin 1 g (309). Day 6±2 microbiological cure in microbiological ITT was 90.9% (460/506) versus 96.2% (229/238). The comparator-minus-zoliflodacin difference was 5.3%, with upper 95% CI 8.6%, below the 12% margin. Events were mostly mild/moderate and no serious events occurred.

Thai researchersRossaphorn Kittiyaowamarn; Nittaya Phanuphak
Theoretical Cosmology71IMPACT SIGNAL
Theoretical model requiring tests

Periodic fractional-action gravity permits cyclic cosmology, with observational support still unclear

The study combines fractional-action cosmology with nonlinear periodic modified gravity in a flat FRW universe. Weighted Friedmann equations define curvature-driven acceleration, with Ricci-scalar oscillations driving expansion-contraction cycles and a fractional parameter controlling amplitude and period. Positive effective coupling and nonnegative scalaron mass support stability for small deviations. Possible star-formation, galaxy, cluster, CMB and primordial-wave signatures are proposed. However, key formulas are missing from the indexed abstract and MCMC/Hubble constraints named in the title are not reported there.

Thai researchersRami Ahmad El-Nabulsi; Waranont Anukool
Geriatric Oral Health71IMPACT SIGNAL
Systematic review and meta-analysis

Low social support is associated with edentulism and irregular dental care after age 75

A PRISMA review searched Medline, Embase and CENTRAL through November 2025 and included 40 studies of adults 75+. Low functional support, or fewer people to rely on, was associated with edentulism (OR 1.21) and irregular dental service use (OR 1.20). Low structural support in living conditions related to edentulism (OR 1.34) and lacking functional dentition (OR 1.41). Other function, behavior and quality-of-life outcomes were sparse and heterogeneous, supporting psychosocial assessment in care planning.

Thai researchersSungkrit Pojmonpiti; Murali Srinivasan; Frauke Müller
Medication and Geriatric Oral Health71IMPACT SIGNAL
Systematic review and meta-analysis

Polypharmacy is associated with roughly twice the odds of dry mouth after age 75

A review screened 3,433 records through April 2025 and included 23 studies: 21 cross-sectional and two cohorts of adults 75+. Polypharmacy was associated with dry mouth (pooled OR 2.05), with consistent links between more medicines, hyposalivation and poor OHAT scores. Multimorbidity was not consistently related to dry mouth or OHAT, and both exposures showed uncertain associations with teeth, edentulism and function. Polypharmacy may affect salivary outcomes partly beyond disease count, but longitudinal evidence is needed.

Thai researchersKittipit Srisanoi; Frauke Müller; Murali Srinivasan
AI Governance and Buddhist Ethics71IMPACT SIGNAL
Qualitative framework evidence

A Buddhist Patisambhida framework recasts university AI governance around purpose, principles, communication and judgment

This qualitative study treats AI as an institutional governance project, not only a teaching or administrative tool. Semistructured interviews with 16 informants, a focus group with nine more participants and document analysis were triangulated. Four themes framed AI as governance and a system-shaping force requiring safeguards, with participant reasoning aligned to Patisambhida: Attha as purpose, Dhamma as principles, Nirutti as communication and Patibhana as judgment, forming a Buddhist Interpretive Governance Framework.

Thai researchersSvangnabha Tuanpusa; Thongdee Sritragarn; Yudthavee Kaewthongyai; Pongpith Tuenpusa
Journal of Interdisciplinary Research in Artificial Intelligence and SocietyRead analysis →
Energy Policy Modeling71IMPACT SIGNAL
National scenario-model evidence

A Thailand 2065 model prioritizes solar, biomass and participation, without yet proving a net-zero pathway

The study develops a GMM-based path model with exogenous variables for Thailand's 2025-2065 policy planning using mixed methods. Technology and energy were most responsive, followed by the social sector. New scenarios emphasize solar adoption, biomass and public participation beyond BCG alone. Final energy use grows 31.75% and GHG emissions 42.35%, or 389.45 MtCO2e, yet the authors classify this below a carrying-capacity threshold and compatible with long-term objectives.

Thai researchersPruethsan Sutthichaimethee; Jindamas Sutthichaimethee; Supakorn Ukumphan; Worawat Sa-Ngiamvibool; Buncha Wattana; Supannika Wattana
AI Literacy and Higher Education71IMPACT SIGNAL
Survey and measurement-model evidence

A four-domain AI-literacy model links use, creation, design and governance with university innovation

Faculty and administrators in private institutions in Sichuan completed a four-domain AILit measure: Engaging, Creating, Designing and Managing. CFA supported reliability (alpha 0.86-0.93); SEM linked all domains to innovation at p0.95, TLI>0.94 and RMSEA

Thai researchersChi Che
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
77IMPACT SIGNAL
Digital Health

AIoT-Based Energy-Efficient Temperature Regulation for Closed-System Greenhouses Using Classification-Based Control

ECTI Transactions on Computer and Information Technology (ECTI-CIT)

Thailand-affiliated authors
Mashida Dangsalae · Attasuntorn Traisuwan · Apidet Booranawong · Kiattisak Sengchuai · Dujdow Buranapanichkit · Nattha Jindapetch
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Multidisciplinary

Structure-Guided Optimization of a LipL32-Targeting DNA Aptamer through Molecular Dynamics and Free-Energy Analysis

ACS Omega

Thailand-affiliated authors
Tri Cao Vu · Boonchoy Soontornworajit · Pichayanoot Rotkrua · Jiraporn Arunpanichlert · Cong Quang Vu · Yuthana Tantirungrotechai
Institutions
Thammasat University
77IMPACT SIGNAL
Multidisciplinary

Bioinformatics-Driven Identification of Flooding-Tolerance Genes and Their Structural and Molecular Characterization in Soybean

ACS Omega

Thailand-affiliated authors
Supaporn Baiya · Methee Juntaropakorn · Sunan Kitjaruwankul · Malinee Promkatkaew
Institutions
Kasetsart University
77IMPACT SIGNAL
Energy and Materials

Integrated Strategy for Sustainable Outdoor Photo-Fermentative Biohydrogen Production: Sequential Optimization, Repeated-Batch Operation, Modular Bioreactor Simulation, and Biomass Valorization

Energies

Thailand-affiliated authors
Netchanok Punriboon · Polson Mahakhan · Khomsorn Lomthaisong · Kowit Suwannahong · Kandasamy Bhuvaneswari · Surachai Wongcharee · Ravinan Chaiyates · Jutaporn Sawaengkaew
Institutions
Khon Kaen University · Burapha University · Mahasarakham University
77IMPACT SIGNAL
Clinical Medicine

Machine learning‑based classification of renal cell carcinoma and upper tract urothelial carcinoma using preoperative hematological markers

Biomedical Reports

Thailand-affiliated authors
Kanrapee Nuwatkrisin · Chanita Panwoon · Kiartisak Senchan · Sakkarn Sangkhamanon · Wunchana Seubwai
Institutions
Khon Kaen University · Vongchavalitkul University
77IMPACT SIGNAL
Clinical Medicine

Extraction Optimization and Preliminary Neuroprotective Evaluation of Asiaticoside and Asiatic Acid from Centella asiatica (L.) Urb Using In Vitro and In Silico Approaches

International Journal of Molecular Sciences

Thailand-affiliated authors
Chaiyasit Winyuchakhrit · Sarin Tadtong · Chatchapong Tangjidapichai · Weerasak Samee
Institutions
Srinakharinwirot University
77IMPACT SIGNAL
Clinical Medicine

Rapid simultaneous detection of katG S315T and rpoB S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay

Microbiology Spectrum

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Nakarin Vutipow · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

High diversity and novel host associations of bat haemosporidian parasites in Cambodia: insights from a nationwide bat survey and multilocus analyses

Parasites & Vectors

Thailand-affiliated authors
Awatsaya Pimsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Chronic Erosive Dermatopathy (CED) Associated with Ectoparasite Infestation in Nile Tilapia Post-Larvae (Oreochromis niloticus Linnaeus, 1758)

Veterinary Sciences

Thailand-affiliated authors
Pornpawit Tanpichai · Onanong Charoenwai · Sayamon Srisuwatanasagul · Patharapol Piamsomboon
Institutions
Mahanakorn University of Technology · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Sesamin Attenuates Interleukin-1β-Induced Inflammation in Human Synovial Cells: Involvement of the Nrf2/HO-1 Pathway and NLRP3 Expression

ACS Omega

Thailand-affiliated authors
Benjawan Wudtiwai · Atitaya Wayupat · Aitthiphon Chongchai · Prachya Kongtawelert · Peraphan Pothacharoen · Thanyaluck Phitak
Institutions
Chiang Mai University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Possible Links Between PM2.5-Induced NLRP3 Inflammasome Activation and Its Role in Lung Cancer Progression and Drug Resistance

International Journal of Molecular Sciences

Thailand-affiliated authors
Thanaphat Worawichitchaikun · Pitchapa Wantanachaisaeng · Teerapat Teeppaibul · Prasit Suwannalert
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Serum FTIR spectral features associated with HDRA-defined gemcitabine sensitivity in cholangiocarcinoma

Biomolecules and Biomedicine

Thailand-affiliated authors
Kanokporn Matra · Patutong Chatchawal · Molin Wongwattanakul · Patipat Rachawangmuang · Sutthiwan Janthamala · Thanaphong Rattanathip · Sirinart Chio‐Srichan · Chanchai Hongsa · Malinee Thanee · Supakan Amontailak · Juthamas Jaimanee · Piyapong Simtong · Anchalee Techasen
Institutions
Khon Kaen University · Synchrotron Light Research Institute
77IMPACT SIGNAL
Clinical Medicine

Image-derived conjunctival hyperemia and clinical ocular surface changes after initiation of topical glaucoma therapy: a prospective longitudinal pilot study

Scientific Reports

Thailand-affiliated authors
Linda Hansapinyo · Nicha Pianwichanpong · Kessara Pathanapitoon · Chanut Hansapinyo · Nutt Hansapinyo · Pichaya Kulniwatcharoen · Karn Patanukhom
Institutions
Chiang Mai University · Rangsit University
77IMPACT SIGNAL
Clinical Medicine

Predictors of the need for airway adjuncts during mask ventilation in Thai adult patients undergoing general anesthesia: A prospective observational study

PLoS ONE

Thailand-affiliated authors
Orarat Karnjanawanichkul · Chanikarn Nuanthong · Ngamjit Pattaravit · Wirat Wasinwong · Sawitree Sricharoenpongchai · Anongluk Samakkee
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of tocilizumab for refractory postsurgical cystoid macular edema

Journal of Ophthalmic Inflammation and Infection

Thailand-affiliated authors
Prapatsorn Ongpalakorn
Institutions
Nopparat Rajathanee Hospital
77IMPACT SIGNAL
Multidisciplinary

A Hierarchical Computer Vision Framework for Continuous Dairy Cow Behavior Monitoring in an Obstructed Free-Stall Barns

Smart Agricultural Technology

Thailand-affiliated authors
Aqeel Raza · Kumail Abbas · H. Hogeveen · Chaidate Inchaisri
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Metabolomic and lipidomic analyses reveal phosphatidylcholine–lysophosphatidylcholine axis alterations in sorafenib-persistent hepatocellular carcinoma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Meng Chieh Yang · Nichawadee Sandech · Sucheewin Krobthong · Likit Rangsirattanakul · Wisuit Pradidarcheep · Arnatchai Maiuthed
Institutions
Srinakharinwirot University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Patient safety events and outcomes in brain tumor surgery : A retrospective cohort study

Journal of Neurosciences in Rural Practice

Thailand-affiliated authors
Kanisorn Sungkaro · Pannawit Chumchue · Thara Tunthanathip · Supaporn Sainamsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a drug–herb interaction alert system integrated into a hospital electronic health record

Pharmacia

Thailand-affiliated authors
Thanatcha Songmuang · Ananya Songmuang · Chonladda Pitchayajittipong · Teeraporn Sadira Supapaan
Institutions
Warin Chamrap Hospital · Ubon Ratchathani University
77IMPACT SIGNAL
Clinical Medicine

Association of adipocyte hypertrophy and ultrasound severity score in lymphedematous limb: a cross-sectional study

Scientific Reports

Thailand-affiliated authors
Parkpoom Piyaman · Panitta Sitthinamsuwan · Sirin Apichonbancha · Nutcha Yodrabum
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Phosphoprotein-enriched proteomics identifies heat shock cognate 71 protein as a host factor supporting chikungunya virus replication in macrophages

Scientific Reports

Thailand-affiliated authors
Nattaya Kamchompoo · Songkran Thongon · Artittaya Athipanyasilp · Tipparat Thiangtrongjit · Kawin Chantima · Onrapak Reamtong · Kobporn Boonnak
Institutions
Siriraj Hospital · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Multidisciplinary providers’ perspectives on timely predialysis arteriovenous access preparation: An exploratory mixed-methods study in upper Northern Thailand

PLoS ONE

Thailand-affiliated authors
Amaraporn Rerkasem · Kochaphan Phirom · Pak Thaichana · Prit Kusirisin · Puntapong Taruangsri · Suwinai Saengyo · Sasinat Pongtam · Wanicha Pungchompoo · Kittipan Rerkasem
Institutions
Chiang Mai University · Nakornping Hospital · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases

Biology

Thailand-affiliated authors
Chalerm Liwsrisakun · Athavudh Deesomchok · Chaicharn Pothirat · Warawut Chaiwong
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort)

Renal Failure

Thailand-affiliated authors
Wanjak Pongsittisak · Jeerath Phannajit · Wonngarm Kittanamongkolchai · Theerasak Tangwonglert · Thawee Chanchairujira · Kraiwiporn Kiattisunthorn · Kornchanok Vareesangthip · Bongkod Surattichaiyakul · Arkom Nongnuch · Surachet Vongsanim · Pantipa Tonsawan · Pornpen Sangthawan · Siribha Changsirikulchai · Phanupong Phutrakool · Peerapat Thanapongsatorn · Pichaya Tantiyavarong · Talerngsak Kanjanabuch · Khajohn Tiranathanagul · Suchai Sritippayawan · Suree Yoowannakul · Vuddhidej Ophascharoensuk · Paweena Susantitaphong
Institutions
Navamindradhiraj University · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Phramongkutklao Hospital · Siriraj Hospital · Rajamangala Institute of kidney disease · Mahidol University · Ramathibodi Hospital · Chiang Mai University · Khon Kaen University · Prince of Songkla University · Srinakharinwirot University · Thammasat University · Bhumibol Adulyadej Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link