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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
HIV Epidemiology75IMPACT SIGNAL
Global surveillance evidence

A 1.39-million-sample map of HIV-1 shows the diversity diagnostics and vaccines must keep pace with

The study assembled 1,395,222 HIV-1 subtype observations from 154 countries between 1990 and 2024 and weighted country estimates using UNAIDS numbers of people living with HIV. In 2020-24, subtype C represented 48.7% globally, followed by subtype A at 11.5% and subtype B at 10.3%. Unique and circulating recombinant forms were also substantial. Regional patterns differed sharply: subtype C dominated southern Africa and south Asia, CRF01_AE southeast Asia, and CRF07_BC increased in east Asia.

Thai researchersDwip Kitayaporn
Cosmology75IMPACT SIGNAL
Unconfirmed emerging signal

DESI DR2 hints at evolving dark energy, but the evidence remains inconclusive

The analysis combined DESI DR2 baryon acoustic oscillations with three Type Ia supernova compilations and a compressed CMB likelihood across eight dark-energy parameterizations. Several models favored the w0 > -1, wa < 0 region and crossed the phantom divide near z about 0.5. However, the preference was driven mainly by the limited LRG1-2 tracers. Mirage-model Bayes factors were only inconclusive to moderate, and no model was robustly preferred by late-time data alone.

Thai researchersG. Mustafa
Chemistry and Clean Energy74IMPACT SIGNAL
Laboratory mechanistic evidence

Oxygen-vacancy engineering at Cu-Zn interfaces advances low-temperature methanol synthesis

Cu/ZnO catalysts for low-temperature methanol synthesis from CO2-containing syngas suffer activity and stability limits. Adding Ba regulated oxygen vacancies at Cu-Zn interfaces, reaching a TOF of 21.2 × 10^-3 s^-1 and methanol space-time yield of 655.17 g kgcat^-1 h^-1. Ba increased exposed Cu0 area, dispersion and basic sites while suppressing sintering. DFT supported interfacial oxygen vacancies as primary active sites.

Thai researchersPrasert Reubroycharoen; Noritatsu Tsubaki
Aging and Data Systems74IMPACT SIGNAL
Qualitative systems evidence

Longitudinal aging data in Asia face funding, workforce and data-sharing bottlenecks

This qualitative study interviewed 33 stakeholders across 13 East and Southeast Asian countries and regions, with additional experts from India, the UK and US. Four themes emerged: structural and contextual barriers; local adaptation of design and logistics; funding and staff-retention threats; and governance, privacy and comparability constraints. Recommendations emphasize policy alignment, multidisciplinary collaboration, harmonization and intentional inclusion of vulnerable populations.

Thai researchersDararatt Anantanasuwong
Global Health79IMPACT SIGNAL
Randomized-trial evidence

Star Homes reduced malaria by 44% and also lowered diarrhea and respiratory infections in children

The trial evaluated the Star Home, a two-story design intended to be insect-proof, cleaner, cooler and smoke-free while providing water and sanitation. Households with children younger than 13 were cluster-randomized to 110 Star Homes or 513 traditional mud and thatched-roof homes. Over three years, children in Star Homes experienced 44% less malaria, 30% less diarrhea and 18% fewer acute respiratory infections; children younger than five also had better height-for-age. The findings support housing as a modifiable determinant of health rather than merely the setting in which disease occurs.

Thai researchersMallika Imwong and Mahidol Oxford Tropical Medicine Research Unit-affiliated coauthors
Cancer Treatment77IMPACT SIGNAL
Phase 3 survival evidence

Perioperative enfortumab vedotin plus pembrolizumab improved survival outcomes in bladder cancer

Patients with muscle-invasive bladder cancer who cannot receive cisplatin have had limited perioperative options. This trial randomized 344 participants to enfortumab vedotin plus pembrolizumab before and after surgery or to surgery alone. At two years, event-free survival was 74.7% versus 39.4%, and overall survival 79.7% versus 63.1%. Pathological complete response also differed markedly, but grade 3 or worse adverse events occurred in 71.3% of the combination group.

Thai researchersPongwut Danchaivijitr
Neurology77IMPACT SIGNAL
Systematic review and meta-analysis

Pure autonomic failure phenoconverted to central synucleinopathies at about 5% per year

Pure autonomic failure may precede brain disorders driven by alpha-synuclein. Across nine longitudinal studies and 900 patients followed for a mean 6.4 years, 270 patients (30%) phenoconverted: 12% to MSA, 11% to DLB and 7% to Parkinson disease. The pooled rate was 5.09 per 100 person-years. Hyposmia favored PD/DLB over MSA, while REM sleep behavior disorder and subtle motor signs were consistent predictors of phenoconversion overall.

Thai researchersSasivimol Virameteekul
Infectious Disease and Public Health76IMPACT SIGNAL
Field detection and surveillance innovation

CRISPR-BEEPs mapped melioidosis exposure and sanitation gaps in northeast Thailand

Burkholderia pseudomallei is difficult to detect environmentally with conventional culture. CRISPR-BEEPs was benchmarked against plate inspection using double-qPCR as reference. Sensitivity was 93.5% versus 19.4%, with specificity of 100% versus 98.0%. Across 15,118 km² in northeast Thailand, the assay detected the organism in 73.3% of groundwater, 32.9% of surface water and 26.2% of piped-water samples. Detection within 10 km of a household was associated with melioidosis (OR 2.74), an association missed by conventional methods.

Thai researchersSukritpong Pakdeerat, Chalita Chomkatekaew, Phumrapee Boonklang and the Thai research network
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
77IMPACT SIGNAL
Digital Health

AIoT-Based Energy-Efficient Temperature Regulation for Closed-System Greenhouses Using Classification-Based Control

ECTI Transactions on Computer and Information Technology (ECTI-CIT)

Thailand-affiliated authors
Mashida Dangsalae · Attasuntorn Traisuwan · Apidet Booranawong · Kiattisak Sengchuai · Dujdow Buranapanichkit · Nattha Jindapetch
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Multidisciplinary

Structure-Guided Optimization of a LipL32-Targeting DNA Aptamer through Molecular Dynamics and Free-Energy Analysis

ACS Omega

Thailand-affiliated authors
Tri Cao Vu · Boonchoy Soontornworajit · Pichayanoot Rotkrua · Jiraporn Arunpanichlert · Cong Quang Vu · Yuthana Tantirungrotechai
Institutions
Thammasat University
77IMPACT SIGNAL
Multidisciplinary

Bioinformatics-Driven Identification of Flooding-Tolerance Genes and Their Structural and Molecular Characterization in Soybean

ACS Omega

Thailand-affiliated authors
Supaporn Baiya · Methee Juntaropakorn · Sunan Kitjaruwankul · Malinee Promkatkaew
Institutions
Kasetsart University
77IMPACT SIGNAL
Energy and Materials

Integrated Strategy for Sustainable Outdoor Photo-Fermentative Biohydrogen Production: Sequential Optimization, Repeated-Batch Operation, Modular Bioreactor Simulation, and Biomass Valorization

Energies

Thailand-affiliated authors
Netchanok Punriboon · Polson Mahakhan · Khomsorn Lomthaisong · Kowit Suwannahong · Kandasamy Bhuvaneswari · Surachai Wongcharee · Ravinan Chaiyates · Jutaporn Sawaengkaew
Institutions
Khon Kaen University · Burapha University · Mahasarakham University
77IMPACT SIGNAL
Clinical Medicine

Machine learning‑based classification of renal cell carcinoma and upper tract urothelial carcinoma using preoperative hematological markers

Biomedical Reports

Thailand-affiliated authors
Kanrapee Nuwatkrisin · Chanita Panwoon · Kiartisak Senchan · Sakkarn Sangkhamanon · Wunchana Seubwai
Institutions
Khon Kaen University · Vongchavalitkul University
77IMPACT SIGNAL
Clinical Medicine

Extraction Optimization and Preliminary Neuroprotective Evaluation of Asiaticoside and Asiatic Acid from Centella asiatica (L.) Urb Using In Vitro and In Silico Approaches

International Journal of Molecular Sciences

Thailand-affiliated authors
Chaiyasit Winyuchakhrit · Sarin Tadtong · Chatchapong Tangjidapichai · Weerasak Samee
Institutions
Srinakharinwirot University
77IMPACT SIGNAL
Clinical Medicine

Rapid simultaneous detection of katG S315T and rpoB S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay

Microbiology Spectrum

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Nakarin Vutipow · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

High diversity and novel host associations of bat haemosporidian parasites in Cambodia: insights from a nationwide bat survey and multilocus analyses

Parasites & Vectors

Thailand-affiliated authors
Awatsaya Pimsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Chronic Erosive Dermatopathy (CED) Associated with Ectoparasite Infestation in Nile Tilapia Post-Larvae (Oreochromis niloticus Linnaeus, 1758)

Veterinary Sciences

Thailand-affiliated authors
Pornpawit Tanpichai · Onanong Charoenwai · Sayamon Srisuwatanasagul · Patharapol Piamsomboon
Institutions
Mahanakorn University of Technology · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Sesamin Attenuates Interleukin-1β-Induced Inflammation in Human Synovial Cells: Involvement of the Nrf2/HO-1 Pathway and NLRP3 Expression

ACS Omega

Thailand-affiliated authors
Benjawan Wudtiwai · Atitaya Wayupat · Aitthiphon Chongchai · Prachya Kongtawelert · Peraphan Pothacharoen · Thanyaluck Phitak
Institutions
Chiang Mai University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Possible Links Between PM2.5-Induced NLRP3 Inflammasome Activation and Its Role in Lung Cancer Progression and Drug Resistance

International Journal of Molecular Sciences

Thailand-affiliated authors
Thanaphat Worawichitchaikun · Pitchapa Wantanachaisaeng · Teerapat Teeppaibul · Prasit Suwannalert
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Serum FTIR spectral features associated with HDRA-defined gemcitabine sensitivity in cholangiocarcinoma

Biomolecules and Biomedicine

Thailand-affiliated authors
Kanokporn Matra · Patutong Chatchawal · Molin Wongwattanakul · Patipat Rachawangmuang · Sutthiwan Janthamala · Thanaphong Rattanathip · Sirinart Chio‐Srichan · Chanchai Hongsa · Malinee Thanee · Supakan Amontailak · Juthamas Jaimanee · Piyapong Simtong · Anchalee Techasen
Institutions
Khon Kaen University · Synchrotron Light Research Institute
77IMPACT SIGNAL
Clinical Medicine

Image-derived conjunctival hyperemia and clinical ocular surface changes after initiation of topical glaucoma therapy: a prospective longitudinal pilot study

Scientific Reports

Thailand-affiliated authors
Linda Hansapinyo · Nicha Pianwichanpong · Kessara Pathanapitoon · Chanut Hansapinyo · Nutt Hansapinyo · Pichaya Kulniwatcharoen · Karn Patanukhom
Institutions
Chiang Mai University · Rangsit University
77IMPACT SIGNAL
Clinical Medicine

Predictors of the need for airway adjuncts during mask ventilation in Thai adult patients undergoing general anesthesia: A prospective observational study

PLoS ONE

Thailand-affiliated authors
Orarat Karnjanawanichkul · Chanikarn Nuanthong · Ngamjit Pattaravit · Wirat Wasinwong · Sawitree Sricharoenpongchai · Anongluk Samakkee
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of tocilizumab for refractory postsurgical cystoid macular edema

Journal of Ophthalmic Inflammation and Infection

Thailand-affiliated authors
Prapatsorn Ongpalakorn
Institutions
Nopparat Rajathanee Hospital
77IMPACT SIGNAL
Multidisciplinary

A Hierarchical Computer Vision Framework for Continuous Dairy Cow Behavior Monitoring in an Obstructed Free-Stall Barns

Smart Agricultural Technology

Thailand-affiliated authors
Aqeel Raza · Kumail Abbas · H. Hogeveen · Chaidate Inchaisri
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Metabolomic and lipidomic analyses reveal phosphatidylcholine–lysophosphatidylcholine axis alterations in sorafenib-persistent hepatocellular carcinoma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Meng Chieh Yang · Nichawadee Sandech · Sucheewin Krobthong · Likit Rangsirattanakul · Wisuit Pradidarcheep · Arnatchai Maiuthed
Institutions
Srinakharinwirot University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Patient safety events and outcomes in brain tumor surgery : A retrospective cohort study

Journal of Neurosciences in Rural Practice

Thailand-affiliated authors
Kanisorn Sungkaro · Pannawit Chumchue · Thara Tunthanathip · Supaporn Sainamsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a drug–herb interaction alert system integrated into a hospital electronic health record

Pharmacia

Thailand-affiliated authors
Thanatcha Songmuang · Ananya Songmuang · Chonladda Pitchayajittipong · Teeraporn Sadira Supapaan
Institutions
Warin Chamrap Hospital · Ubon Ratchathani University
77IMPACT SIGNAL
Clinical Medicine

Association of adipocyte hypertrophy and ultrasound severity score in lymphedematous limb: a cross-sectional study

Scientific Reports

Thailand-affiliated authors
Parkpoom Piyaman · Panitta Sitthinamsuwan · Sirin Apichonbancha · Nutcha Yodrabum
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Phosphoprotein-enriched proteomics identifies heat shock cognate 71 protein as a host factor supporting chikungunya virus replication in macrophages

Scientific Reports

Thailand-affiliated authors
Nattaya Kamchompoo · Songkran Thongon · Artittaya Athipanyasilp · Tipparat Thiangtrongjit · Kawin Chantima · Onrapak Reamtong · Kobporn Boonnak
Institutions
Siriraj Hospital · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Multidisciplinary providers’ perspectives on timely predialysis arteriovenous access preparation: An exploratory mixed-methods study in upper Northern Thailand

PLoS ONE

Thailand-affiliated authors
Amaraporn Rerkasem · Kochaphan Phirom · Pak Thaichana · Prit Kusirisin · Puntapong Taruangsri · Suwinai Saengyo · Sasinat Pongtam · Wanicha Pungchompoo · Kittipan Rerkasem
Institutions
Chiang Mai University · Nakornping Hospital · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases

Biology

Thailand-affiliated authors
Chalerm Liwsrisakun · Athavudh Deesomchok · Chaicharn Pothirat · Warawut Chaiwong
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort)

Renal Failure

Thailand-affiliated authors
Wanjak Pongsittisak · Jeerath Phannajit · Wonngarm Kittanamongkolchai · Theerasak Tangwonglert · Thawee Chanchairujira · Kraiwiporn Kiattisunthorn · Kornchanok Vareesangthip · Bongkod Surattichaiyakul · Arkom Nongnuch · Surachet Vongsanim · Pantipa Tonsawan · Pornpen Sangthawan · Siribha Changsirikulchai · Phanupong Phutrakool · Peerapat Thanapongsatorn · Pichaya Tantiyavarong · Talerngsak Kanjanabuch · Khajohn Tiranathanagul · Suchai Sritippayawan · Suree Yoowannakul · Vuddhidej Ophascharoensuk · Paweena Susantitaphong
Institutions
Navamindradhiraj University · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Phramongkutklao Hospital · Siriraj Hospital · Rajamangala Institute of kidney disease · Mahidol University · Ramathibodi Hospital · Chiang Mai University · Khon Kaen University · Prince of Songkla University · Srinakharinwirot University · Thammasat University · Bhumibol Adulyadej Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link