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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Restoring Culturally Essential Floor-Sitting in Transfemoral Prosthesis Users: A Six-Week Pilot Randomized Within-Subject Trial

A pilot randomised within-subject trial in 14 unilateral transfemoral prosthesis users compared a low-profile, femoral-adducted Asian Transfemoral Socket with each participant's usual socket after six weeks of ATS use. Twelve participants attained cross-legged sitting and six additional participants attained side-sitting with ATS, alongside comfort and quality-of-life signals. Six-minute walking distance, four-square-step balance and daily steps did not differ significantly; the small sample could not exclude clinically important harm.

Thai researchersNatthawan Sutthison · Nang Myat Myat Moe · Yasmin Nutchamlong · Marisa Amattayakul · Mathurin Rairat · Woratee Dacharux · Kazuhiko Sasaki
Clinical Medicine89IMPACT SIGNAL
Global potential

Effects of a Home-Based Fall Prevention Program in Older Lower Limb Prosthesis Users: A Randomized Controlled Trial

A randomised controlled trial assigned 44 older lower-limb prosthesis users to usual care or education plus 16 home exercises three times weekly for eight weeks; 41 completed follow-up. Change in Timed Up and Go did not differ between groups, nor did static balance or balance confidence. No falls were reported during the study, but the sample and follow-up were too small to establish fall prevention or definitive lack of benefit. The null finding applies to this relatively high-mobility study population.

Thai researchersPrawina Sakulkosol · Pieter U Dijkstra · Kazuhiko Sasaki · Jutamanee Poonsiri
Genomic Public Health and Thalassaemia88IMPACT SIGNAL
Regional policy evidence synthesis

Thalassaemia prevention in Asia: progress, challenges, and future directions

This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured approaches, combining public awareness, carrier screening, genetic counselling, and prenatal diagnosis. Measurable success was clearest in Singapore and to a more limited extent Thailand. Many countries still face fragmented services, weak national coordination, workforce shortages, insufficient epidemiological data, and financial, technological, cultural, and social barriers. This is a regional health-system synthesis, not a comparative policy trial.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Vaccination Behaviour and Public Health89IMPACT SIGNAL
Observational cross-sectional evidence

Hepatitis B Vaccination Intention and Influencing Factors among College Students in Huanggang, Hubei, China: A Protection Motivation Theory-Based Cross-Sectional Study

This Protection Motivation Theory cross-sectional study surveyed 1,130 students aged 18–26 at three universities in Huanggang, Hubei, China, during April–May 2025. The authors dichotomized a 1–10 intention item into low scores of 1–6 and high scores of 7–10; 58.9% were in the high-intention group. In adjusted analysis, hepatitis B knowledge, vaccine knowledge, preventive behaviour, perceived severity, self-efficacy, and response efficacy were associated with higher odds of high intention, while perceived response cost was associated with lower odds. The findings identify intervention targets but do not show that changing them raises actual vaccination uptake.

Thai researchersCong Zhang · Phatcha Hirunwatthanakul · Nachalida Yukalang
Thalassaemia Epidemiology and Public Health Systems88IMPACT SIGNAL
Regional epidemiological synthesis

The Epidemiology of Thalassaemia Syndromes in Southeast Asia

This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and produce phenotypes ranging from asymptomatic carriage to lifelong transfusion dependence. Although a small set of mutations often dominates within each country, the regional spectrum is complex and population data remain incomplete. The paper highlights blood shortages, consanguinity in some settings, gender inequities, migration, and low awareness, and recommends national registries, premarital or prenatal screening, coordinated blood systems, and culturally sensitive education.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Sustainable Livestock and Agriculture89IMPACT SIGNAL
Animal-trial evidence with modeled environmental outcomes

Crude-Glycerin Leucaena Pellets Improve Goat Feed Efficiency, but Methane Reduction Is Modeled

Thai researchers tested Leucaena leucocephala pellets containing 0–15% crude glycerin in 32 male Boer × Thai native goats for 90 days. Intake fell slightly, but gain-to-feed ratio, fermentation indicators, and modeled economics improved. Methane and greenhouse-gas reductions were estimated from a stoichiometric model rather than direct emissions measurements.

Thai researchersNirandorn Nakdaeng · Sirirat Buaphan · Kanok Chaovapasee
Electric Mobility and Energy Infrastructure85IMPACT SIGNAL
Techno-economic case-study scenario analysis

Techno-Economic Assessment of EV Charging Infrastructure in Residential Buildings in Nonthaburi, Thailand

This Nonthaburi residential-building case study compared two 60-kW DC chargers, one 60-kW DC plus two 22-kW AC chargers, and four 22-kW AC chargers. Assumptions included a seven-year project, 5.5% discount rate, mean selling price of THB7.25/kWh, service time of 4, 6, or 8 hours per day, and electricity costs of THB4.50, 4.73, or 4.95/kWh, giving 27 scenarios. All three portfolios were financially feasible under the specified conditions. Two DC chargers gave the strongest return at eight hours per day and THB4.50/kWh, while four AC chargers better fit long parking durations and lower capital and maintenance costs.

Thai researchersChatchaphon Ketviriyakit · Pasura Aungkulanon · Lakkana Ruekkasaem
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
75IMPACT SIGNAL
Engineering

Sequential enzymatic hydrolysis and valorization of cassava pulp waste: A multi-scale process optimization for glucose production

Industrial Crops and Products

Thailand-affiliated authors
Phatthariya Phromngulueam · Waewdao Dathong · Apichat Boontawan · Lek Wantha
Institutions
Suranaree University of Technology · Nakhon Ratchasima Rajabhat University
75IMPACT SIGNAL
Engineering

Impact of Trap Centers on the Scintillation Performance of TlSr2Br5:Eu2+ Single Crystal

Nuclear Engineering and Technology

Thailand-affiliated authors
J. Kaewkhao · S. Kothan
Institutions
Nakhon Pathom Rajabhat University · Chiang Mai University
75IMPACT SIGNAL
Global Public Health

Maternal and Neonatal Outcomes of Supervised versus Unsupervised Medical Abortion: A Systematic Review and Meta-Analysis

National Journal of Community Medicine

Thailand-affiliated authors
Anuj Kumar Pandey · Sharmila Bhandari
Institutions
Mahidol University
75IMPACT SIGNAL
Clinical Medicine

Bioelectrical impedance-derived total body water for predicting exertional rhabdomyolysis-induced acute kidney injury during military training: a prospective cohort study

BMC Nephrology

Thailand-affiliated authors
Chaken Maniyan · Bancha Satirapoj · Ouppatham Supasyndh · Narongrit Siriwattanasit
Institutions
Phramongkutklao Hospital
75IMPACT SIGNAL
Energy and Materials

Tuning Na+ Solvation and Association inFluorine-Free NaClO4 Electrolytes via Carbonate Cosolvents

ACS Omega

Thailand-affiliated authors
Phitchapa Ausamanwet Zijdemans · Ali Hassan · Soorathep Kheawhom · Manaswee Suttipong
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

Reproductive Biology and Mating Frequency in the Common Bed Bugs, Cimex lectularius , and Tropical Bed Bugs, Cimex hemipterus (Hemiptera: Cimicidae)

Entomological Research

Thailand-affiliated authors
Pranita Sukha · Natthaset Khunhom · Dae‐Yun Kim
Institutions
Kasetsart University
75IMPACT SIGNAL
Clinical Medicine

Complete remission after rituximab therapy of pemphigus: Real-world evidence on dosing regimens and re-treatment strategies

JID Innovations

Thailand-affiliated authors
Chuda Rujitharanawong · Sasima Tongsai
Institutions
Siriraj Hospital · Mahidol University
75IMPACT SIGNAL
Clinical Medicine

Comprehensive Characterization of a Novel Broad-Host-Range Lytic Salmonella Phage WP110 and Its Biocontrol Potential Across the Broiler Value Chain

Antibiotics

Thailand-affiliated authors
Wattana Pelyuntha · Wichanan Wannasrichan · Haemarat Khongkhai · David Yembilla Yamik · Mingkwan Yingkajorn · Kitiya Vongkamjan
Institutions
Walailak University · Kasetsart University · Prince of Songkla University
75IMPACT SIGNAL
Global Public Health

Water consumption in heifers fed rice DDGS and wheat-groundnut straw mixture

Journal of Livestock Science

Thailand-affiliated authors
M Pandey · S.V. Shah · YG Patel · K.N Wadhwani
Institutions
Department of Livestock Development
75IMPACT SIGNAL
Clinical Medicine

The Effects of Jasmine and Champaca Aromatherapy Combined with Acupressure on Sleep Quality in Older Adults with Non-Communicable Diseases: A Quasi-Experimental Study in Rural Northern Thailand

Journal of Health Research

Thailand-affiliated authors
Sriwan Chutithamniti · Katekaew Seangpraw · Prapaporn Tulwattanakul · Manuchet Manotham · Parichat Ong-Artborirak · Wannita Sakulwattana · Surangkana Chairinkam · Phatcharee Pimalram · Wichida Larsomsri
Institutions
Thai Health Promotion Foundation · University of Phayao · Navamindradhiraj University · Vajira Hospital
75IMPACT SIGNAL
Clinical Medicine

Age, Hypertension, and Physical Inactivity as Dominant Risk Factors for Stroke: A Population-Based Study in Yogyakarta, Indonesia

MAHESA Malahayati Health Student Journal

Thailand-affiliated authors
Muhammad Abdi Riyantono · Ajeng Tias Endarti · Sumiati Bedah
Institutions
Thammasat University
75IMPACT SIGNAL
Global Public Health

Challenges in Treatment Node Classification for Network Meta‐Analysis of Non‐Pharmacological Interventions: Insights From a Researcher Survey

Journal of Evidence-Based Medicine

Thailand-affiliated authors
Kansak Boonpattharatthiti · Nathorn Chaiyakunapruk · Teerapon Dhippayom
Institutions
Burapha University · Naresuan University · Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

Peripheral blood mononuclear cell proteomic profiling reveals cytoskeletal- and chromatin-associated protein signatures in autism spectrum disorder

Brain Behavior & Immunity - Health

Thailand-affiliated authors
Marlieke L. van Erp · Wasana Yuwattana · Chayanit Poolcharoen · Thanit Saeliw · Sittiruk Roytrakul · Natchaya Vanwong · Pon Trairatvorakul · Weerasak Chonchaiya · Tewarit Sarachana
Institutions
Chulalongkorn University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
75IMPACT SIGNAL
Clinical Medicine

Time-resolved proteomic adaptation of multidrug-resistant Acinetobacter baumannii to antimicrobial stress induced by partially purified fraction from Caesalpinia pulcherrima flower using DEqMS

Microbiology Spectrum

Thailand-affiliated authors
Wanchat Sirisarn · Thammarit Khamplod · Narumon Phaonakrop · Kiattawee Choowongkomon · Kriskamol Na Jom · Sittiruk Roytrakul · Sompop Saeheng
Institutions
Kasetsart University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology · Prince of Songkla University
75IMPACT SIGNAL
Clinical Medicine

Single-cell transcriptomic analysis of cutaneous squamous cell carcinoma identifies an NR1H3-associated angiogenic macrophage state

Frontiers in Immunology

Thailand-affiliated authors
Yong He · Ting Tian · Liming Li · Leqi Qian · Tian Tian · Xiaoke Wang · Yuancheng Li · Mingjun Jiang
Institutions
Institute of Dermatology
75IMPACT SIGNAL
Clinical Medicine

Hybrid artificial intelligence framework for patient emotion recognition in dentistry

Frontiers in Oral Health

Thailand-affiliated authors
Kanoksak Wattanachote · Taechinee Ratanawimon · Phawit Phanchantraurai · Wanlida Suphasri-itsara · Panupat Phumpatrakom · Samroeng Inglam · Siriwan Suebnukarn
Institutions
Mahidol University · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

Dual bispecific protein engagers targeting mesothelin and NECTIN2 deliver CD3/CD28 signals to activate cytotoxic T cells against colorectal cancer patient-derived organoids

Scientific Reports

Thailand-affiliated authors
Suyanee Thongchot · Kamonlapat Supimon · Nattaporn Phanthaphol · Pattara Kanoksing · Titaporn Mitchasin · Woramin Riansuwan · Siriluck Prapasrivorakul · Pornraksa Ovartchaiyapong · Aitsariya Mongkhonsupphawan · Surat Phumphuang · Mutita Junking · Pa-thai Yenchitsomanus · Peti Thuwajit · Chanitra Thuwajit
Institutions
Siriraj Hospital · Mahidol University · Naresuan University
75IMPACT SIGNAL
Clinical Medicine

Investigation of the Prevalence of the HLA‐B*15:02 Allele in the Asian Populations: A Comprehensive Analysis Through Using AFND

Health Science Reports

Thailand-affiliated authors
Mohitosh Biswas · Maliheh Ershadian · Chonlaphat Sukasem
Institutions
Mahidol University · Ramathibodi Hospital · Bumrungrad International Hospital
75IMPACT SIGNAL
Clinical Medicine

Inherited C5aR2 deficiency leads to uncontrolled inflammatory T cell responses and autoinflammatory disease 2309676

The Journal of Immunology

Thailand-affiliated authors
Ayden Case · Jubayer Rahman
Institutions
National Institute of Health of Thailand
75IMPACT SIGNAL
Clinical Medicine

Prevention of recurrence of severe combined immunodeficiency through preimplantation genetic testing: a case study of a novel IL2RG variant and confirmed maternal somatic mosaicism in Thailand

Journal of Assisted Reproduction and Genetics

Thailand-affiliated authors
Napadon Yaibuates · Pongpet Benjaponwattana · Busarin Boonyacheeva · Jitti Saksantisuk
Institutions
Nakornthon Hospital · PTT Public Company Limited (Thailand)
75IMPACT SIGNAL
Clinical Medicine

From MyACR to MyμAlbumin: Clinical Validation of a High‐Precision, Real‐Time Immunoturbidimetric PoC Device for Early Chronic Kidney Disease Detection

Journal of Clinical Laboratory Analysis

Thailand-affiliated authors
Tullayakorn Plengsuriyakarn · Wanna Chai่jaroenkul · Napaporn Youngvises · Kridsada Sirisabhabhorn · Waraporn Bubpha · Kesara Na‐Bangchang
Institutions
Thammasat University · Thammasat University Hospital
75IMPACT SIGNAL
Clinical Medicine

Exosomal PD-L1 level in plasma as a predictive marker for prognostic and clinical correlation in NSCLC

Scientific Reports

Thailand-affiliated authors
Krisda Jitrakbumrung · Phuritat Sookananchai · Meena Tanapirakgul · Thutchima Khieota · Poorichaya Somparn · Trairak Pisitkun · Padet Tanangterapong · Panot Sainamthip
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

From biological evidence to clinical application: a scoping review of oral fluid biomarkers in type 2 diabetic periodontitis

Frontiers in Oral Health

Thailand-affiliated authors
Sukumaran Anil
Institutions
Chulalongkorn University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link