A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals
Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.
Sue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. NewtonMahidol University · Mahidol Oxford Tropical Medicine Research Unit (MORU)
Paired samples from treatment-naïve gastric-cancer patients and controls showed substantially higher richness and diversity with mucosal brushing than biopsy. Brushing detected lower diversity and altered composition in cancer, whereas biopsy did not. Sampling method shapes microbiome signals, but causation and diagnostic utility are unproven.
Gizzard lesions in Thai chickens contained intranuclear inclusions, in-situ hybridization signal and PCR-confirmed fowl adenovirus. Hexon and fibre sequencing identified FAdV-8a strain FAdV8a_NPT_KU001_25, closer to a gizzard-tropic than an inclusion-body-hepatitis strain. Association is supported, but causation remains unproven.
A two-clinic Chiang Mai study of 150 MSM and transgender women found clinically significant depression in 5.3% of PrEP users and 13.3% of non-users. Mean depression was lower among PrEP users, while suicidal ideation occurred in 5.3% with no group difference.
An exploratory case-control study of 37 Thai adults with confirmed beta-lactam hypersensitivity identified HLA-DQA1*01:04 and HLA-DQA1*05:05 candidate signals after Bonferroni correction, with the latter stronger for immediate reactions. Small size, population controls and sensitivity-instability mean the findings are not ready for screening or drug avoidance.
Twenty male esports players were randomised to cup stacking three days weekly for four weeks or usual training. Post-intervention salivary alpha-amylase fell within the experimental group and differed significantly from controls.
Giant freshwater prawns received control diets or 10% and 20% fishmeal replacement with L. plantarum TISTR1284-fermented Leucaena for two weeks. Fermented diets increased immune markers and reduced post-A. hydrophila mortality by 26.14%, with normal intestinal morphology.
The systematic review identified 17 reports representing 15 randomised trials with 6,256 participants; 2,216 contributed to overweight subgroup analyses. The meta-analysis included 12 studies and 1,728 pregnant women with overweight. Interventions combined diet and physical activity, often with goal setting, self-monitoring and digital or remote follow-up.
A seven-country prospective cohort of 1,703 adults with HIV found Mycobacterium tuberculosis bloodstream infection predominantly among inpatients and associated it with higher 30-day mortality.
An evaluation of 1,838 stored sera from seven countries found that a second-generation Hcp1 antibody test had sensitivity ranging from 48% to 92%, with specificity varying by country and comparison group.
Thai researchersHasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Analysis of Thai national claims from 2015–2023 identified 60,916 paediatric hepatobiliary admissions. Admission rates were broadly stable and in-hospital mortality declined, while hepatic failure remained a high-risk condition.
An international expert statement spanning 22 countries reviews links among food systems, cardiometabolic health and the Sustainable Development Goals. It advocates plant-forward traditional diets rich in whole grains, legumes, vegetables, fruit, nuts and spices, with meat used sparingly.
The multicentre survey analysed 604 patients from 25 Thai hospitals between December 2023 and March 2024. SSRIs accounted for 70.2% of prescriptions, followed by TCAs at 13.9% and trazodone at 12.7%. The most common diagnoses were depressive disorders (55.0%), substance use disorders (15.2%) and psychotic disorders (13.7%). Clinicians cited limited availability (21.9%), reimbursement arrangements (36.3%) and patient finances (33.9%) as prescribing constraints.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
76IMPACT SIGNAL
Clinical Medicine
Modulating Oxidative Stress and Inflammatory Responses of Aloe vera–Silk Fibroin–Chitosan Gel Formulation in Macrophages and Diabetic Fibroblasts Under Chronic Inflammatory-like Conditions
Gels
Thailand-affiliated authors
Phassorn Khumfu · Sukunya Ross · Gareth M. Ross · Jarupa Viyoch
Institutions
Naresuan University
76IMPACT SIGNAL
Clinical Medicine
Development and validation of a Ramathibodi Poison Center scoring system to predict follow-up necessity in hospitalized patients: a retrospective study
Mahasarakham University · Rajamangala University of Technology Isan · Burapha University
76IMPACT SIGNAL
Clinical Medicine
Predictive performance of the Modified Frailty Index and ASA-PS classification for 30-day mortality after esophagectomy in patients with esophageal cancer
Nakhon Si Thammarat Rajabhat University · Prince of Songkla University
76IMPACT SIGNAL
Clinical Medicine
Clonal diversity underpins distinct modes of recurrence in hepatocellular carcinoma: the PLANet cohort study
Gut
Thailand-affiliated authors
Chairat Bunchaliew
Institutions
National Cancer Institute of Thailand
76IMPACT SIGNAL
Multidisciplinary
Understandings of child and youth participation in the context of Thailand’s policy and programme development through the lens of children, young people and policymakers
Asia Pacific Journal of Social Work and Development
Thailand-affiliated authors
Chanon Komonmarn
Institutions
Thammasat University
76IMPACT SIGNAL
Clinical Medicine
Comparative Effectiveness of Oral Ivermectin, 1% Permethrin Shampoo, and 4% Dimethicone Liquid Gel in Treatment of Pediculosis Capitis among School Children in Chachoengsao Province, Thailand
Does bronchoalveolar lavage lymphocytosis predict prognosis in fibrotic hypersensitivity pneumonitis, and is this relationship influenced by low-dose immunomodulatory therapy at the time of BAL?
Frontiers in Medicine
Thailand-affiliated authors
Punchalee Kaenmuang
Institutions
Prince of Songkla University
76IMPACT SIGNAL
Clinical Medicine
A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality
Scientific Reports
Thailand-affiliated authors
Richard M. Hoglund · Kevin C. Kobylinski · Podjanee Jittamala · Borimas Hanboonkunupakarn · Narenrit Wamaket · Patchara Sriwichai · Siriporn Phasomkusolsil · Nicholas J. White · Nicholas P. J. Day · Joel Tarning
Institutions
Mahidol Oxford Tropical Medicine Research Unit · Mahidol University · Armed Forces Research Institute of Medical Science
76IMPACT SIGNAL
Environmental Engineering
From seafloor litter to living substrate: A first assessment of litter composition and plastic-associated fouling communities in the Gulf of Thailand
Chiang Mai University · Ministry of Public Health · Institute of Dermatology · National Science and Technology Development Agency · Thailand Science Park · National Center for Genetic Engineering and Biotechnology
75IMPACT SIGNAL
Clinical Medicine
Emerging Oxidative, Metabolic, and Inflammatory States Associated with Working in Charcoal-Grill Shops: An Exploratory Study
