Phetchabun Screens 97.3% for HCV; 96.4% of SVR12-Evaluable Patients Are Cured, but Transmission Elimination Is Unproven
Phetchabun’s micro-elimination programme linked fingerstick anti-HCV testing, HCV-RNA confirmation, and 12-week sofosbuvir/velpatasvir treatment through primary-care and district-hospital services across all 11 districts under universal health coverage. From 2020 to April 2026, 389,547 of 400,567 targeted people were screened (97.25%); 14,845 of 18,340 anti-HCV-reactive participants received RNA confirmation (80.94%), identifying 10,996 active infections. Of 8,961 treatment-eligible patients, 8,842 received therapy (98.67%); among 6,719 evaluated at SVR12, 6,474 were cured (96.35%). The programme demonstrates province-scale test-to-treat feasibility, but not yet the incidence or mortality reductions required for elimination.
Wijitra Phaengkha · Pornjarim Nilyanimit · Nungruthai Suntronwong · Jiratchaya Puenpa · Duong Hoang Huy Le · Saranya Ngamnimit · Pattama Janpathip · Lapasrada Kamput · Kawin Thongnoi · Wanalee Toomta · Phatcha Wohanklong · Jarunlak Saokeaw · Niphapornt Thammajit · Suwannee Rerngleum · Ananyalak Yoisara · Nitiya Srisuk · Jidapa Suwannachat · Anchalee Karagate · Rujipat Wasitthankasem · Yong PoovorawanNam Nao Hospital, Phetchabun · Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University · Phetchabun Provincial Public Health Office · Phetchabun Hospital · Buengsamphan Hospital · Lomsak Hospital · Chondaen Hospital · Si Thep Hospital · Wang Pong Hospital · Wichianburi Hospital · Lomkao Crown Prince Hospital · Nongphai Hospital · Khao Kho Hospital · National Center for Genetic Engineering and Biotechnology, NSTDA · The Royal Society of Thailand
A post hoc analysis of the DEN-301 placebo arm followed 30,620.6 person-years, identifying 560 virologically confirmed dengue cases among 9,698 febrile illnesses; 142 cases, or 25.4%, were hospitalized.
A 20-year-old man on automated peritoneal dialysis developed vague abdominal symptoms, weight loss and declining ultrafiltration. Repeated dialysate cultures, acid-fast staining and molecular tests were negative despite mononuclear-predominant leukocytosis. Contrast CT identified peritoneal nodules, CT peritoneography showed a trapped dialysate pocket, and targeted biopsy demonstrated necrotising granulomatous inflammation. Tissue culture grew M. kansasii resistant to rifampicin, moxifloxacin and ciprofloxacin.
HITAP reviewed 278 HTA capacity-strengthening activities in 25 countries from 2010 to mid-2025. Asia accounted for 151 activities and 128 engagements were programmatic rather than ad hoc. Knowledge sharing represented 26% and research or project collaboration 21%. Among 11 African partner countries, only three had programmatic engagement, accounting for 30 activities.
Morphology combined with ITS, LSU, rpb2 and β-tub phylogenies distinguished Nigropunctata pseudohydei as a new species and confirmed the first Thai record of N. complanata.
Thai researchersZaw Lin Tun · Digvijayini Bundhun · Kevin D. Hyde
An eight-country perspective argues that telemedicine, wearables and home sensors, augmented AI and mobile health can distribute expertise, observe symptoms between visits and support self-management, particularly where neurologists are scarce. Impact depends on infrastructure, interoperability, workforce, governance and equity-first hybrid care, not devices alone.
DJC6219 and NK62157 were isolated from municipal wastewater and characterised through host-range assays, electron microscopy, stability, multiplicity-of-infection optimisation, growth kinetics and genomics.
The authors review challenges in estimating preventable AMR burden and advocate explicit counterfactuals, confounding control and principled combination of individual studies.
Thai researchersCherry Lim · Sue J. Lee · Yin Mo · Ben S. Cooper
Ten Asia-Pacific experts developed 11 consensus statements on mild traumatic brain injury and use of GFAP/UCH-L1 within 12 hours. Final agreement was 90-100%, emphasizing biomarkers as adjuncts while clinical assessment and locally available imaging remain central.
RGD-functionalized cannabidiol lipid nanoparticles increased cellular uptake threefold and in-vitro BBB transport by 65%, while reducing inflammatory and oxidative markers. In a preclinical Alzheimer's model, cognition, Aβ/tau pathology, metabolism and gut-barrier indicators improved. The findings are promising but not evidence in patients.
Researchers used the UNDRR Stop Disasters online game with students, water professionals and community members in Thailand and Malaysia. A post-game survey of 35 participants found high enjoyment, lively interaction and perceived reinforcement of declarative flood-management knowledge.
Among 1,870 critically ill patients with acute kidney injury, sodium and potassium from arterial blood-gas analysers showed relatively good agreement with central laboratory values, with potassium having the narrowest limits. Clinically meaningful discrepancies occurred in 7.0% of sodium, 14.1% of potassium and 31.4% of chloride measurements, so rapid bedside results should support rather than replace reference testing.
This multicentre secondary analysis used the validated 2018–2020 TH-SOSGOQ 2.0 database. The full cohort included 68 patients and the reliability/construct-validity cohort 64. Mean age was 57 years and 55.9% were women. Internal consistency was 0.832 and test-retest ICCs ranged from 0.52 to 0.85.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
76IMPACT SIGNAL
Clinical Medicine
Modulating Oxidative Stress and Inflammatory Responses of Aloe vera–Silk Fibroin–Chitosan Gel Formulation in Macrophages and Diabetic Fibroblasts Under Chronic Inflammatory-like Conditions
Gels
Thailand-affiliated authors
Phassorn Khumfu · Sukunya Ross · Gareth M. Ross · Jarupa Viyoch
Institutions
Naresuan University
76IMPACT SIGNAL
Clinical Medicine
Development and validation of a Ramathibodi Poison Center scoring system to predict follow-up necessity in hospitalized patients: a retrospective study
Mahasarakham University · Rajamangala University of Technology Isan · Burapha University
76IMPACT SIGNAL
Clinical Medicine
Predictive performance of the Modified Frailty Index and ASA-PS classification for 30-day mortality after esophagectomy in patients with esophageal cancer
Nakhon Si Thammarat Rajabhat University · Prince of Songkla University
76IMPACT SIGNAL
Clinical Medicine
Clonal diversity underpins distinct modes of recurrence in hepatocellular carcinoma: the PLANet cohort study
Gut
Thailand-affiliated authors
Chairat Bunchaliew
Institutions
National Cancer Institute of Thailand
76IMPACT SIGNAL
Multidisciplinary
Understandings of child and youth participation in the context of Thailand’s policy and programme development through the lens of children, young people and policymakers
Asia Pacific Journal of Social Work and Development
Thailand-affiliated authors
Chanon Komonmarn
Institutions
Thammasat University
76IMPACT SIGNAL
Clinical Medicine
Comparative Effectiveness of Oral Ivermectin, 1% Permethrin Shampoo, and 4% Dimethicone Liquid Gel in Treatment of Pediculosis Capitis among School Children in Chachoengsao Province, Thailand
Does bronchoalveolar lavage lymphocytosis predict prognosis in fibrotic hypersensitivity pneumonitis, and is this relationship influenced by low-dose immunomodulatory therapy at the time of BAL?
Frontiers in Medicine
Thailand-affiliated authors
Punchalee Kaenmuang
Institutions
Prince of Songkla University
76IMPACT SIGNAL
Clinical Medicine
A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality
Scientific Reports
Thailand-affiliated authors
Richard M. Hoglund · Kevin C. Kobylinski · Podjanee Jittamala · Borimas Hanboonkunupakarn · Narenrit Wamaket · Patchara Sriwichai · Siriporn Phasomkusolsil · Nicholas J. White · Nicholas P. J. Day · Joel Tarning
Institutions
Mahidol Oxford Tropical Medicine Research Unit · Mahidol University · Armed Forces Research Institute of Medical Science
76IMPACT SIGNAL
Environmental Engineering
From seafloor litter to living substrate: A first assessment of litter composition and plastic-associated fouling communities in the Gulf of Thailand
Chiang Mai University · Ministry of Public Health · Institute of Dermatology · National Science and Technology Development Agency · Thailand Science Park · National Center for Genetic Engineering and Biotechnology
75IMPACT SIGNAL
Clinical Medicine
Emerging Oxidative, Metabolic, and Inflammatory States Associated with Working in Charcoal-Grill Shops: An Exploratory Study