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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
Rational Prescribing and Medication Safety74IMPACT SIGNAL
Evidence of global relevance

Assessment of Inappropriate Omeprazole Prescribing, Associated Factors and Financial Impact in the Outpatient Department of a General Hospital in Thailand

A review of 347 outpatient prescriptions for 229 patients from January-June 2025 at one Thai general hospital classified 58.2% of omeprazole prescriptions as potentially inappropriate. Of these, 75.2% lacked an appropriate indication, followed by inappropriate duration.

Thai researchersSaranporn Srithonrat · Chayanat Pongsathabordee · Satawat Kulworahathai · Chidawan Prapat · Aticha Jamratkittiwan · Nichakan Jitakson · Taniya Paiboonvong
Endocrine Emergency Medicine74IMPACT SIGNAL
Evidence of global relevance

Prognostic factors and prognostic risk score of 30-day all-cause mortality in thyroid storm

A retrospective cohort of 115 thyroid-storm patients at a Thai tertiary center had 13% 30-day mortality. An eight-point score using male sex, hypertension, SOFA at least 2, and GCS at most 10 achieved apparent AUC 0.81 and bootstrap-corrected AUC 0.79.

Thai researchersPakpoom Chantrapitak · Worapaka Manosroi · Sittikul Thipbumrung · Pichitchai Atthakomol
Companion-Animal AMR and One Health74IMPACT SIGNAL
Evidence of global relevance

Genomic Characterization, Antimicrobial Resistance Profiles, and tetA Nucleotide Substitutions of Escherichia coli Isolated from Healthy Dogs in Thailand

Fecal samples from 200 healthy dogs at 50 clinics in Chiang Mai and Nakhon Si Thammarat during January-March 2026 yielded 66 E. coli isolates. Resistance reached 100% for ampicillin, 84.85% for piperacillin, 60.61% for ceftriaxone, 56.06% for tetracycline, and 47% multidrug resistance.

Thai researchersRavisa Warin · Naparat Suttidate · Wanna Suriyasathaporn · Witaya Suriyasathaporn · Ratchadaporn Boripun
Microalgae and Energy Harvesting74IMPACT SIGNAL
Evidence of global relevance

Immobilized microalgae-driven triboelectric nanogenerators for sustainable bioelectricity production

Thai researchers immobilized living Chlorella vulgaris TISTR 8580 at different densities on aluminum electrodes as a triboelectric layer for solid-solid and solid-liquid interactions, reporting peak output of 110 V and 330 nA.

Thai researchersChalampol Janpum · Tanakit Komkhum · Naratip Vittayakorn · Kamon Thinsurat · Chawalit Ngamcharussrivichai · Pichaya In-na
Alternative Proteins, Drying, and Flavor73IMPACT SIGNAL
Evidence of global relevance

Drying-Induced Structural and Oxidative Transformations in Sustainable Proteins: Impact on Physicochemical Properties and Flavor-Binding Functionality

This review proposes a structure-process-function framework explaining how hot-air, heat-pump, microwave, and freeze-drying differently unfold, aggregate, and oxidize plant and marine proteins, changing how volatile flavors are bound, retained, and released.

Thai researchersYoon Hlaine Barani · Passakorn Kingwascharapong · Saroat Rawdkuen
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
73IMPACT SIGNAL
Multidisciplinary

Just how far off target are we? Measuring unmet pre-exposure prophylaxis need among men who have sex with men and transgender women in Asia-Pacific

Sexual Health

Thailand-affiliated authors
Nittaya Phanuphak
Institutions
Bangkok University
73IMPACT SIGNAL
Digital Health

An analogical argumentation framework for argumentative local explainers

Argument & Computation

Thailand-affiliated authors
Nguyen Duy Hung · Thanaruk Theeramunkong
Institutions
Thammasat University · The Royal College Of Anesthesiologists Of Thailand
73IMPACT SIGNAL
Clinical Medicine

Alpha-Mangostin in Acute Kidney Injury: Molecular Mechanisms, Regulated Cell Death, and Translational Opportunities

Antioxidants

Thailand-affiliated authors
Atthaphong Phongphithakchai · Nawanwat C. Pattaranggoon · Kraiyasak Wongna · Ratana Netphakdee · Aman Tedasen · Chutima Jansakun · Wiyada Kwanhian Klangbud · Jongkonnee Thanasai · Moragot Chatatikun
Institutions
Prince of Songkla University · Walailak University · Nakhon Phanom University · Mahasarakham University
73IMPACT SIGNAL
Global Public Health

Biotechnological Advances of Lactic Acid Bacteria in Maghrebian Countries: An Updated Review

Biotechnology and Applied Biochemistry

Thailand-affiliated authors
Pankaj Koirala · Nilesh Prakash Nirmal
Institutions
Mahidol University
73IMPACT SIGNAL
Energy and Materials

Fe-doped BiVO4/g-C3N4 heterojunction for efficient tetracycline degradation under low-intensity UV irradiation

Scientific Reports

Thailand-affiliated authors
Supakorn Boonyuen
Institutions
Thammasat University
73IMPACT SIGNAL
Clinical Medicine

Parametric study of electrohydrodynamic flow and heat transfer in a wind tunnel using thermochromic liquid crystals and smoke tracing

Scientific Reports

Thailand-affiliated authors
K. Wongcharee · D. Chutrakul · V. Chuwattanakul · S. Eiamsa-ard
Institutions
Mahanakorn University of Technology · King Mongkut's Institute of Technology Ladkrabang
73IMPACT SIGNAL
Clinical Medicine

Evidence- and opinion-based consensus from Delphi round 1 of the Asian aplastic anemia recommendation development

International Journal of Hematology

Thailand-affiliated authors
Surapol Issaragrisil
Institutions
Siriraj Hospital · Mahidol University
73IMPACT SIGNAL
Clinical Medicine

Severe fever with thrombocytopenia syndrome complicated by invasive pulmonary aspergillosis and septic shock: a case report highlighting the role of mNGS

Frontiers in Medicine

Thailand-affiliated authors
Mingzhi Fan
Institutions
Police General Hospital
73IMPACT SIGNAL
Environmental Engineering

Biphasic Oxidative Carboxylation of Aliphatic Olefins With H 2 O 2 to Produce Useful Cyclic Carbonates

Advanced Synthesis & Catalysis

Thailand-affiliated authors
Surajchaya Kheawmuan · Suthida Kaewsai · Wuttichai Natongchai · Pipat Na Ranong · Silvano Del Gobbo · Valerio D’Elia
Institutions
Vidyasirimedhi Institute of Science and Technology
73IMPACT SIGNAL
Clinical Medicine

Multifactorial influences on lung function in farmers: personal, occupational, and health-related factors

Journal of Environmental Science and Health Part B

Thailand-affiliated authors
Patchareeya Amput · Ajchamon Thammachai · Saisunee Konsanit · Patcharin Phrompao · Sirima Wongphon
Institutions
University of Phayao
73IMPACT SIGNAL
Environmental Engineering

A novel multi-criteria group decision-making technique in traffic flow and safety assessment using interval-valued complex spherical fuzzy soft set

Scientific Reports

Thailand-affiliated authors
Saalam Ali · Hamza Naveed
Institutions
King Mongkut's University of Technology Thonburi
73IMPACT SIGNAL
Clinical Medicine

Exploring the Reasons Behind the Low Purchase Rate of CPAP Machines Among Adult Patients With Obstructive Sleep Apnea Through Qualitative Research

Social Marketing Quarterly

Thailand-affiliated authors
Bundit Sawunyavisuth · Darunee Jongudomkarn · Kittisak Sawanyawisuth
Institutions
Khon Kaen University
73IMPACT SIGNAL
Environmental Engineering

Preharvest temperature treatments influence physiological traits, secondary metabolites, and volatile compounds in holy basil under controlled environment conditions

Scientific Reports

Thailand-affiliated authors
P. Boonkorkaew · Niafnan Hayi-asan · Akira Thongtip · Wannida Sae-Tang · Atikorn Panya · Natthaporn Phonsatta · Sujichon Thangvichien · Prapussorn Yingcharoen · Panita Chutimanukul
Institutions
Kasetsart University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
73IMPACT SIGNAL
Environmental Engineering

Nationwide and regional evidence on PM2.5-mortality in a tropical climate: Risks persist below standard and under climate extremes

Ecotoxicology and Environmental Safety

Thailand-affiliated authors
Phichet Khunthong · Panuwat Vittayapraparat · Sitthichok Puangthongthub
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN

Journal of the American Chemical Society

Thailand-affiliated authors
Cody A. Loy · Shawn E. Vinogradsky · Darci J. Trader
Institutions
Mahidol University
73IMPACT SIGNAL
Multidisciplinary

CD163+ perivascular macrophages in schizophrenia: a research framework for testing macrophage-related mechanisms

Frontiers in Psychiatry

Thailand-affiliated authors
Chavit Tunvirachaisakul · Michael Maes
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of intrathecal morphine compared to peripheral nerve blocks in patients underwent foot and ankle surgery:  A propensity score analysis

F1000Research

Thailand-affiliated authors
Preeyaphan Arunakul · Prapasri Kulalert · Marut Arunakul
Institutions
Thammasat University
73IMPACT SIGNAL
Global Public Health

Histological development of the stomach and hepatopancreas of two laboratory-reared sesarmid crabs, Episesarma species (Decapoda: sesarmidae)

Discover Developmental Biology

Thailand-affiliated authors
Chanyut Sudtongkong · Supparat Kong-oh · Piyamat Kongtueng · Anan Kenthao · W. Tongtako · Narit Thaochan · Supapong Imsonpang · Sinlapachai Senarat
Institutions
Rajamangala University of Technology Srivijaya · Chiang Mai University · Naresuan University · Prince of Songkla University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link