Twenty-Year Review Finds Zoonotic NTDs Remain Hidden in Laos and Cambodia as Diagnostics and Surveillance Stay Fragmented
The article synthesises publications and long-running surveillance at the animal–human interface in Laos and Cambodia, covering Taenia solium, Trichinella, Streptococcus suis, rickettsiae, melioidosis, hepatitis E, and Japanese encephalitis. Its recurring message is diagnostic invisibility caused by limited laboratories and fragmented human–animal–environment systems, with risks embedded in smallholder livestock, informal slaughter, raw-meat consumption, wet markets, and animal-contact occupations. It proposes scaling abattoir, animal-sentinel, market, and environmental surveillance alongside livelihood-aware risk communication. This is a narrative synthesis, not a systematic review or one national survey, so it maps patterns and gaps rather than estimating current national burden.
Stuart D. Blacksell · Syseng Khounsy · Jarunee Siengsanan-Lamont · Lida Kong · Jaison B. Kolenchery · Paul N. Newton · Nicholas P. J. DayMahidol University · Mahidol Oxford Tropical Medicine Research Unit
Paired samples from treatment-naïve gastric-cancer patients and controls showed substantially higher richness and diversity with mucosal brushing than biopsy. Brushing detected lower diversity and altered composition in cancer, whereas biopsy did not. Sampling method shapes microbiome signals, but causation and diagnostic utility are unproven.
Gizzard lesions in Thai chickens contained intranuclear inclusions, in-situ hybridization signal and PCR-confirmed fowl adenovirus. Hexon and fibre sequencing identified FAdV-8a strain FAdV8a_NPT_KU001_25, closer to a gizzard-tropic than an inclusion-body-hepatitis strain. Association is supported, but causation remains unproven.
A two-clinic Chiang Mai study of 150 MSM and transgender women found clinically significant depression in 5.3% of PrEP users and 13.3% of non-users. Mean depression was lower among PrEP users, while suicidal ideation occurred in 5.3% with no group difference.
An exploratory case-control study of 37 Thai adults with confirmed beta-lactam hypersensitivity identified HLA-DQA1*01:04 and HLA-DQA1*05:05 candidate signals after Bonferroni correction, with the latter stronger for immediate reactions. Small size, population controls and sensitivity-instability mean the findings are not ready for screening or drug avoidance.
Twenty male esports players were randomised to cup stacking three days weekly for four weeks or usual training. Post-intervention salivary alpha-amylase fell within the experimental group and differed significantly from controls.
Giant freshwater prawns received control diets or 10% and 20% fishmeal replacement with L. plantarum TISTR1284-fermented Leucaena for two weeks. Fermented diets increased immune markers and reduced post-A. hydrophila mortality by 26.14%, with normal intestinal morphology.
The systematic review identified 17 reports representing 15 randomised trials with 6,256 participants; 2,216 contributed to overweight subgroup analyses. The meta-analysis included 12 studies and 1,728 pregnant women with overweight. Interventions combined diet and physical activity, often with goal setting, self-monitoring and digital or remote follow-up.
A seven-country prospective cohort of 1,703 adults with HIV found Mycobacterium tuberculosis bloodstream infection predominantly among inpatients and associated it with higher 30-day mortality.
An evaluation of 1,838 stored sera from seven countries found that a second-generation Hcp1 antibody test had sensitivity ranging from 48% to 92%, with specificity varying by country and comparison group.
Thai researchersHasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Analysis of Thai national claims from 2015–2023 identified 60,916 paediatric hepatobiliary admissions. Admission rates were broadly stable and in-hospital mortality declined, while hepatic failure remained a high-risk condition.
An international expert statement spanning 22 countries reviews links among food systems, cardiometabolic health and the Sustainable Development Goals. It advocates plant-forward traditional diets rich in whole grains, legumes, vegetables, fruit, nuts and spices, with meat used sparingly.
The multicentre survey analysed 604 patients from 25 Thai hospitals between December 2023 and March 2024. SSRIs accounted for 70.2% of prescriptions, followed by TCAs at 13.9% and trazodone at 12.7%. The most common diagnoses were depressive disorders (55.0%), substance use disorders (15.2%) and psychotic disorders (13.7%). Clinicians cited limited availability (21.9%), reimbursement arrangements (36.3%) and patient finances (33.9%) as prescribing constraints.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
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Clinical Medicine
Core needle biopsy-derived breast cancer microtumors enable functional drug-response testing for precision oncology
Ratchathani University · Ubon Ratchathani University · Ubon Ratchathani Rajabhat University · Buriram Rajabhat University · Kalasin University
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Clinical Medicine
Determination of Exploratory Metastasis Biomarkers in Cancer of Unknown Primary Using Metastatic Colon Cancer as a Model: RNA Sequencing Bioinformatics Analysis
Mahidol University · Prapokklao Hospital · Rambhai Barni Rajabhat University · Burapha University · Asian Institute of Technology · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
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Environmental Engineering
Modeling the impact of climatic variables on cereal crop production in the Terai region of Nepal
Mahidol University · Ramathibodi Hospital · Ramathibodi Chakri Naruebodindra Hospital
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Clinical Medicine
Association of Cardiovascular Risk Factors with Atherosclerotic Changes in Lower-Limb Donor Arteries for Free Flap Reconstruction: A CTA-Based Multivariate Analysis.
