Phetchabun Screens 97.3% for HCV; 96.4% of SVR12-Evaluable Patients Are Cured, but Transmission Elimination Is Unproven
Phetchabun’s micro-elimination programme linked fingerstick anti-HCV testing, HCV-RNA confirmation, and 12-week sofosbuvir/velpatasvir treatment through primary-care and district-hospital services across all 11 districts under universal health coverage. From 2020 to April 2026, 389,547 of 400,567 targeted people were screened (97.25%); 14,845 of 18,340 anti-HCV-reactive participants received RNA confirmation (80.94%), identifying 10,996 active infections. Of 8,961 treatment-eligible patients, 8,842 received therapy (98.67%); among 6,719 evaluated at SVR12, 6,474 were cured (96.35%). The programme demonstrates province-scale test-to-treat feasibility, but not yet the incidence or mortality reductions required for elimination.
Wijitra Phaengkha · Pornjarim Nilyanimit · Nungruthai Suntronwong · Jiratchaya Puenpa · Duong Hoang Huy Le · Saranya Ngamnimit · Pattama Janpathip · Lapasrada Kamput · Kawin Thongnoi · Wanalee Toomta · Phatcha Wohanklong · Jarunlak Saokeaw · Niphapornt Thammajit · Suwannee Rerngleum · Ananyalak Yoisara · Nitiya Srisuk · Jidapa Suwannachat · Anchalee Karagate · Rujipat Wasitthankasem · Yong PoovorawanNam Nao Hospital, Phetchabun · Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University · Phetchabun Provincial Public Health Office · Phetchabun Hospital · Buengsamphan Hospital · Lomsak Hospital · Chondaen Hospital · Si Thep Hospital · Wang Pong Hospital · Wichianburi Hospital · Lomkao Crown Prince Hospital · Nongphai Hospital · Khao Kho Hospital · National Center for Genetic Engineering and Biotechnology, NSTDA · The Royal Society of Thailand
Paired samples from treatment-naïve gastric-cancer patients and controls showed substantially higher richness and diversity with mucosal brushing than biopsy. Brushing detected lower diversity and altered composition in cancer, whereas biopsy did not. Sampling method shapes microbiome signals, but causation and diagnostic utility are unproven.
Gizzard lesions in Thai chickens contained intranuclear inclusions, in-situ hybridization signal and PCR-confirmed fowl adenovirus. Hexon and fibre sequencing identified FAdV-8a strain FAdV8a_NPT_KU001_25, closer to a gizzard-tropic than an inclusion-body-hepatitis strain. Association is supported, but causation remains unproven.
A two-clinic Chiang Mai study of 150 MSM and transgender women found clinically significant depression in 5.3% of PrEP users and 13.3% of non-users. Mean depression was lower among PrEP users, while suicidal ideation occurred in 5.3% with no group difference.
An exploratory case-control study of 37 Thai adults with confirmed beta-lactam hypersensitivity identified HLA-DQA1*01:04 and HLA-DQA1*05:05 candidate signals after Bonferroni correction, with the latter stronger for immediate reactions. Small size, population controls and sensitivity-instability mean the findings are not ready for screening or drug avoidance.
Twenty male esports players were randomised to cup stacking three days weekly for four weeks or usual training. Post-intervention salivary alpha-amylase fell within the experimental group and differed significantly from controls.
Giant freshwater prawns received control diets or 10% and 20% fishmeal replacement with L. plantarum TISTR1284-fermented Leucaena for two weeks. Fermented diets increased immune markers and reduced post-A. hydrophila mortality by 26.14%, with normal intestinal morphology.
The systematic review identified 17 reports representing 15 randomised trials with 6,256 participants; 2,216 contributed to overweight subgroup analyses. The meta-analysis included 12 studies and 1,728 pregnant women with overweight. Interventions combined diet and physical activity, often with goal setting, self-monitoring and digital or remote follow-up.
A seven-country prospective cohort of 1,703 adults with HIV found Mycobacterium tuberculosis bloodstream infection predominantly among inpatients and associated it with higher 30-day mortality.
An evaluation of 1,838 stored sera from seven countries found that a second-generation Hcp1 antibody test had sensitivity ranging from 48% to 92%, with specificity varying by country and comparison group.
Thai researchersHasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Analysis of Thai national claims from 2015–2023 identified 60,916 paediatric hepatobiliary admissions. Admission rates were broadly stable and in-hospital mortality declined, while hepatic failure remained a high-risk condition.
An international expert statement spanning 22 countries reviews links among food systems, cardiometabolic health and the Sustainable Development Goals. It advocates plant-forward traditional diets rich in whole grains, legumes, vegetables, fruit, nuts and spices, with meat used sparingly.
The multicentre survey analysed 604 patients from 25 Thai hospitals between December 2023 and March 2024. SSRIs accounted for 70.2% of prescriptions, followed by TCAs at 13.9% and trazodone at 12.7%. The most common diagnoses were depressive disorders (55.0%), substance use disorders (15.2%) and psychotic disorders (13.7%). Clinicians cited limited availability (21.9%), reimbursement arrangements (36.3%) and patient finances (33.9%) as prescribing constraints.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
73IMPACT SIGNAL
Clinical Medicine
Association of APOC3 promoter variants with hypertriglyceridemia and metabolic dysfunction-associated steatotic liver disease (MASLD) in a Thai cohort
Siriraj Hospital · Mahidol University · HRH Princess Maha Chakri Sirindhorn Medical Center · Srinakharinwirot University
73IMPACT SIGNAL
Digital Health
Assessment of nitrogen status and spatial distribution to enhance growth and inflorescence quality in Dendrobium Sonia ‘Earsakul’ using near-infrared hyperspectral imaging
The Journal of Horticultural Science and Biotechnology
Flexible Edible Materials from Extrusion-Plasticized Modified Cassava Starches with Maltol and Ethyl Maltol: Molecular Interactions, Mechanical Properties, and Antioxidant and Antimicrobial Activities
Cross-kingdom RNA in plant–microbe interactions: from molecular interactions to next-generation crop protection
Stress Biology
Thailand-affiliated authors
Borala Liyanage D. Deepali · Kevin D. Hyde · K. W. Thilini Chethana
Institutions
Mae Fah Luang University
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Clinical Medicine
Efficacy and safety of colistin monotherapy versus colistin-based combination therapy in pediatric patients with multidrug-resistant gram-negative infections: A propensity score analysis
Fecal microbiome dynamics in sows and piglets following the Bacillus probiotics supplementation during the transition and lactation periods under tropical conditions
Chulalongkorn University · Mahanakorn University of Technology
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Environmental Engineering
Potential of Pycnoporus sanguineus (NUOL-PPK.02) for Bioremediation of Chlorpyrifos and Azoxystrobin in an Autoclaved Soil-Based Biomixture: A Pot Incubation Study
Effect of hybrid layer dominance on mechanical performance, moisture diffusion, and biodegradation of kenaf/pineapple leaf fiber-reinforced PLA laminated biocomposites
Scientific Reports
Thailand-affiliated authors
Baranitharan Paramasivam · Malinee Sriariyanun
Institutions
King Mongkut's University of Technology North Bangkok
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Environmental Engineering
The awareness-distress paradox: Traffic-related air pollution awareness and psychological distress among the parents of urban schoolchildren in a northeastern province, Thailand
Chulalongkorn University · Thailand National Metal and Materials Technology Center · Thailand Science Park
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Clinical Medicine
Virucidal activity and differential antiviral efficacy of curcuminoid preparations against porcine epidemic diarrhea virus and feline infectious peritonitis virus
Kasetsart University · Prince of Songkla University
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Engineering
Hybrid Passive–Active Cooling Using a Single Closed Two-Phase Cooling System Integrated with Forced Aeration for Thermal Stabilization and Humidity Control in Paddy Storage
Shinawatra University · Pathumthani University · Bangkokthonburi University · King Mongkut's Institute of Technology Ladkrabang
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Multidisciplinary
The investigation of the interaction between durian (Durio zibethinus Murr.) polyphenols and human serum proteins: Molecular docking analysis and effects of processing
Walailak University · Mae Fah Luang University · Burapha University
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Global Public Health
Spatial determinants of disability prevalence in myanmar: A district-level spatial regression analysis
Journal of Public Health and Development
Thailand-affiliated authors
Wor Mi Thi · Kyaw Min Htike
Institutions
Khon Kaen University
73IMPACT SIGNAL
Clinical Medicine
Faecal microbiota transplantation for skin disease: intriguing biology, premature therapy?
British Journal of Dermatology
Thailand-affiliated authors
John A. McGrath
Institutions
Institute of Dermatology
73IMPACT SIGNAL
Global Public Health
Impact of pedigree completeness on genomic–polygenic evaluations for milk yield, fat percentage, and age at first calving in Thai multibreed dairy cattle
