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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Maternal Metabolic Health77IMPACT SIGNAL
Prospective biomarker cohort evidence

First-trimester plasma asprosin and its association with gestational diabetes mellitus: A prospective cohort study

This prospective cohort enrolled 302 low-risk singleton pregnancies at 10–14 weeks, measured plasma asprosin, and assessed gestational diabetes at 24–28 weeks. Ninety-eight participants (32.5%) developed GDM. Asprosin varied with BMI but did not discriminate later GDM, with an AUC of 0.516. The study provides a first-trimester reference range and evidence against using this biomarker alone for early screening.

Thai researchersSathaphone Inthavong · Phudit Jatavan · Sirinart Kumfu · Nipon Chattipakorn · Theera Tongsong
Diabetes and Complications77IMPACT SIGNAL
Local case-control evidence

Factors associated with microvascular complications in patients with type 2 diabetes in Mueang District, Phitsanulok Province

A hospital-based case-control study in Mueang Phitsanulok compared 130 patients with physician-diagnosed microvascular complications and 260 controls. Diabetes for at least seven years, blood pressure of 140/90 mmHg or higher and high stress were associated with complications. The extremely large association for no metformin use had a very wide CI and cannot establish a direct protective drug effect.

Thai researchersNathamon Kamolvoradej · Patipat Vongruang · Sakesun Thongtip · Kongprai Tunsuchart
Mental Health and Family Caregiving85IMPACT SIGNAL
Instrument development and validation evidence

Psychometric Validation of a Family Adaptation Measure for First-Episode Psychosis

Researchers developed a culturally grounded measure of family adaptation and caregiving role engagement in Thai first-episode psychosis. Focus groups with 17 caregivers, item development and piloting preceded validation in 343 caregivers from four psychiatric hospitals, split into EFA (171) and CFA (172) groups. The 23-item, four-dimension FACRI explained 68.71% of variance and had overall Cronbach's alpha of 0.94. This is preliminary validity evidence, not a diagnostic test or proof of patient benefit.

Thai researchersWilai Napa · Nantiya Ekathikhomkit · Pennapa Unsanit · Patraporn Bhatarasakoon
Water, Sediment and the Mekong Basin77IMPACT SIGNAL
Catchment-scale modelling framework

A hydrological-year stratified regionalization framework for sediment rating curves in the largest tributary of the Mekong River

In the Mun River Basin, the Mekong's largest tributary, researchers developed a sediment-rating-curve regionalisation framework for sparse monitoring conditions. Flood, normal and drought years were separated before comparing regression and catchment-similarity approaches. Sediment-discharge behaviour varied by hydrological condition, while the preferred method depended on slope and erosion-related catchment attributes, arguing against a single static curve for every place and year.

Thai researchersNantawoot Inseeyong · Pavisorn Chuenchum · Kwanchai Pakoksung · Jeerapong Laonamsai
Malaria and Vaccine Development73IMPACT SIGNAL
Sequence and computational prediction evidence

Mapping HLA-restricted T-cell epitopes within conserved regions of Plasmodium vivax circumsporozoite protein from Thailand

PvCSP sequences from 34 P. vivax-infected patients in Southern Thailand were compared with 281 public sequences from Brazil and Vanuatu. IEDB predictions mapped T-cell epitopes against prevalent Thai HLA alleles. Conserved N- and C-terminal regions contained dense CD4+ and CD8+ targets, and cumulative modelled population coverage reached 95.86% in Southeast Asia. These are vaccine-design candidates, not observed immunogenicity or protection.

Thai researchersPongsakorn Thawornpan · Sasicha Suksapan · Thiranai Kitingen · Piyawan Kochayoo · Pachara Tianpothong · Patchanee Chootong
Crop Protection and Agricultural Bioproducts72IMPACT SIGNAL
Laboratory antagonism and preliminary toxicity evidence

Antagonistic Activity and Preliminary Toxicity Assessment of a Bacillus subtilis TU089 Bioproduct Against Phytophthora palmivora Causing Durian Root and Stem Rot

Five Bacillus strains were screened against Phytophthora palmivora MNP13, which causes durian root and stem rot. B. subtilis TU089 inhibited growth by 76.56±0.23% on plates and was developed into an encapsulated product at about 10^8 CFU/mL that retained activity comparable to fresh cells. Cell assays yielded IC10 values of 1,090 µg/mL in MRC-5 and 309.82 µg/mL in HaCaT cells; acute oral testing found no significant adverse effects under the studied conditions. Efficacy remains laboratory-based and safety preliminary.

Thai researchersPonchanok Datmanee · Apipu Ariyachayut · Thunyatorn Yimsoo · Dusit Athinuwat · Wilawan Chuaboon
Malaria and Adjunctive Treatment82IMPACT SIGNAL
Phase I safety and dose evidence

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial

A phase I trial in Kenyan and Zambian children hospitalised with severe malaria tested adjunctive sevuparin as three infusions at 0, 8 and 16 hours. Twenty-three children were enrolled and 20 were included in the primary analysis. Model-guided escalation and dose-limiting APTT prolongation led to a maximum tolerated dose of 3 mg/kg per infusion. This is an early safety and dose-finding result, not evidence of clinical efficacy.

Thai researchersNicholas P. J. Day · Arjen M. Dondorp
Air Pollution and Health85IMPACT SIGNAL
Provincial observational time-series evidence

Health risks and lag effects of ambient PM2.5 exposure on respiratory and cardiovascular mortality and morbidity in Ratchaburi, Thailand

Using a distributed lag non-linear model, the study linked ambient PM2.5 with respiratory and cardiovascular mortality and morbidity in Ratchaburi during 2015–2019, from the exposure day through seven subsequent days. Across all ages and genders, each 10 µg/m³ increase was associated with 5.42% higher respiratory mortality at lag 0 and 2.69% higher respiratory morbidity over lag 0–6.

Thai researchersSitthipong Pengjan · Sébastien Bonnet · Savitri Garivait
Maternal Health and High-Risk Pregnancy77IMPACT SIGNAL
Multi-hospital case-control evidence

Predictors of preeclampsia with severe features: A multi-center analysis of maternal and health system factors in Thai tertiary hospitals

Across four Thai tertiary hospitals, a case-control study compared 156 postpartum women with preeclampsia: 52 with and 104 without severe features, alongside data from 111 nurse-midwives. After adjustment for antenatal visits and gravidity, prior preeclampsia was associated with 5.99-fold higher odds of severe features. Moderate knowledge and higher BMI showed inverse associations, which should not be treated as causal protection.

Thai researchersTippawan Boonyaporn · Piyanun Limruangrong · Ameporn Ratinthorn · Thitipong Tankumpuan
Ethnic Health and Non-Communicable Disease81IMPACT SIGNAL
Grounded-theory qualitative evidence

Balancing tradition, modernity, and spirituality: A grounded theory of non-communicable disease management in the Tai Saek Ethnic Group of Thailand

A qualitative study of 18 Tai Saek adults from two Nakhon Phanom villages described NCD management as a non-linear negotiation among traditional lifeways, changing agriculture and diet, generational relations, spirituality and biomedicine. Participants did not simply reject modern care; they selectively combined ancestor worship with clinical treatment. This could support cultural empowerment, while heavy reliance on rituals could delay biomedical care.

Thai researchersAmornrat Sangsaikaew · Wasana Ruaisungnoen
Cancer Supportive Care89IMPACT SIGNAL
Mixed-methods evidence synthesis

Experiences and coping strategies among cancer patients with cancer-related cognitive impairment treated with chemotherapy: a mixed-methods systematic review

This mixed-methods systematic review synthesized 21 studies of chemotherapy-treated cancer patients with cancer-related cognitive impairment. Memory, concentration, and executive-function problems affected daily life, work, relationships, and emotions. Coping included memory aids, self-regulation, task modification, lifestyle changes, and social support. Perceived benefit is not trial-proven clinical efficacy.

Thai researchersJing Li · Wasana Ruaisungnoen · Supan Unjai · Parichat Wonggom
Environment and Risk Management89IMPACT SIGNAL
Regional model-validation evidence

The Socio-Economic Asymmetry Index (SEA): A Framework for Identifying Vulnerability–Exposure Mismatch in Flood-Prone Agricultural Landscapes

This study introduces the Socio-Economic Asymmetry Index (SEA) to identify agricultural areas where socioeconomic vulnerability outweighs physical flood exposure. The framework was tested at 63,010 sampling points in Thailand's Upper Chi River Basin using satellite and land-use data, six composite indices, Random Forest, and SHAP. About one quarter of the study area fell into high or very high asymmetry classes. The result is a spatial modelling tool for prioritising field assessment and support; it does not establish which factors causally produce flood losses.

Thai researchersPatiwat Littidej · Jiradech Majandang · Benjamabhorn Pumhirunroj
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
73IMPACT SIGNAL
Clinical Medicine

Dual bispecific protein engager–armed T cells targeting BCMA and B7-H3 overcome antigen heterogeneity in multiple myeloma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Thanida Chanpong · Nunghathai Sawasdee · Kamonlapat Supimon · Thanich Sangsuwannukul · Thaweesak Chieochansin · Pa‐thai Yenchitsomanus · Mutita Junking
Institutions
Siriraj Hospital
73IMPACT SIGNAL
Clinical Medicine

Evaluation of acoustic pulse and cold laser therapies for the treatment of dairy cows with subclinical mastitis under organic management conditions

Frontiers in Veterinary Science

Thailand-affiliated authors
Guy Jodarski
Institutions
Ministry of Agriculture and Cooperatives
73IMPACT SIGNAL
Multidisciplinary

Just how far off target are we? Measuring unmet pre-exposure prophylaxis need among men who have sex with men and transgender women in Asia-Pacific

Sexual Health

Thailand-affiliated authors
Nittaya Phanuphak
Institutions
Bangkok University
73IMPACT SIGNAL
Digital Health

An analogical argumentation framework for argumentative local explainers

Argument & Computation

Thailand-affiliated authors
Nguyen Duy Hung · Thanaruk Theeramunkong
Institutions
Thammasat University · The Royal College Of Anesthesiologists Of Thailand
73IMPACT SIGNAL
Clinical Medicine

Alpha-Mangostin in Acute Kidney Injury: Molecular Mechanisms, Regulated Cell Death, and Translational Opportunities

Antioxidants

Thailand-affiliated authors
Atthaphong Phongphithakchai · Nawanwat C. Pattaranggoon · Kraiyasak Wongna · Ratana Netphakdee · Aman Tedasen · Chutima Jansakun · Wiyada Kwanhian Klangbud · Jongkonnee Thanasai · Moragot Chatatikun
Institutions
Prince of Songkla University · Walailak University · Nakhon Phanom University · Mahasarakham University
73IMPACT SIGNAL
Global Public Health

Biotechnological Advances of Lactic Acid Bacteria in Maghrebian Countries: An Updated Review

Biotechnology and Applied Biochemistry

Thailand-affiliated authors
Pankaj Koirala · Nilesh Prakash Nirmal
Institutions
Mahidol University
73IMPACT SIGNAL
Energy and Materials

Fe-doped BiVO4/g-C3N4 heterojunction for efficient tetracycline degradation under low-intensity UV irradiation

Scientific Reports

Thailand-affiliated authors
Supakorn Boonyuen
Institutions
Thammasat University
73IMPACT SIGNAL
Clinical Medicine

Parametric study of electrohydrodynamic flow and heat transfer in a wind tunnel using thermochromic liquid crystals and smoke tracing

Scientific Reports

Thailand-affiliated authors
K. Wongcharee · D. Chutrakul · V. Chuwattanakul · S. Eiamsa-ard
Institutions
Mahanakorn University of Technology · King Mongkut's Institute of Technology Ladkrabang
73IMPACT SIGNAL
Clinical Medicine

Evidence- and opinion-based consensus from Delphi round 1 of the Asian aplastic anemia recommendation development

International Journal of Hematology

Thailand-affiliated authors
Surapol Issaragrisil
Institutions
Siriraj Hospital · Mahidol University
73IMPACT SIGNAL
Clinical Medicine

Severe fever with thrombocytopenia syndrome complicated by invasive pulmonary aspergillosis and septic shock: a case report highlighting the role of mNGS

Frontiers in Medicine

Thailand-affiliated authors
Mingzhi Fan
Institutions
Police General Hospital
73IMPACT SIGNAL
Environmental Engineering

Biphasic Oxidative Carboxylation of Aliphatic Olefins With H 2 O 2 to Produce Useful Cyclic Carbonates

Advanced Synthesis & Catalysis

Thailand-affiliated authors
Surajchaya Kheawmuan · Suthida Kaewsai · Wuttichai Natongchai · Pipat Na Ranong · Silvano Del Gobbo · Valerio D’Elia
Institutions
Vidyasirimedhi Institute of Science and Technology
73IMPACT SIGNAL
Clinical Medicine

Multifactorial influences on lung function in farmers: personal, occupational, and health-related factors

Journal of Environmental Science and Health Part B

Thailand-affiliated authors
Patchareeya Amput · Ajchamon Thammachai · Saisunee Konsanit · Patcharin Phrompao · Sirima Wongphon
Institutions
University of Phayao
73IMPACT SIGNAL
Environmental Engineering

A novel multi-criteria group decision-making technique in traffic flow and safety assessment using interval-valued complex spherical fuzzy soft set

Scientific Reports

Thailand-affiliated authors
Saalam Ali · Hamza Naveed
Institutions
King Mongkut's University of Technology Thonburi
73IMPACT SIGNAL
Clinical Medicine

Exploring the Reasons Behind the Low Purchase Rate of CPAP Machines Among Adult Patients With Obstructive Sleep Apnea Through Qualitative Research

Social Marketing Quarterly

Thailand-affiliated authors
Bundit Sawunyavisuth · Darunee Jongudomkarn · Kittisak Sawanyawisuth
Institutions
Khon Kaen University
73IMPACT SIGNAL
Environmental Engineering

Preharvest temperature treatments influence physiological traits, secondary metabolites, and volatile compounds in holy basil under controlled environment conditions

Scientific Reports

Thailand-affiliated authors
P. Boonkorkaew · Niafnan Hayi-asan · Akira Thongtip · Wannida Sae-Tang · Atikorn Panya · Natthaporn Phonsatta · Sujichon Thangvichien · Prapussorn Yingcharoen · Panita Chutimanukul
Institutions
Kasetsart University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
73IMPACT SIGNAL
Environmental Engineering

Nationwide and regional evidence on PM2.5-mortality in a tropical climate: Risks persist below standard and under climate extremes

Ecotoxicology and Environmental Safety

Thailand-affiliated authors
Phichet Khunthong · Panuwat Vittayapraparat · Sitthichok Puangthongthub
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN

Journal of the American Chemical Society

Thailand-affiliated authors
Cody A. Loy · Shawn E. Vinogradsky · Darci J. Trader
Institutions
Mahidol University
73IMPACT SIGNAL
Multidisciplinary

CD163+ perivascular macrophages in schizophrenia: a research framework for testing macrophage-related mechanisms

Frontiers in Psychiatry

Thailand-affiliated authors
Chavit Tunvirachaisakul · Michael Maes
Institutions
Chulalongkorn University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link