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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Maternal Metabolic Health77IMPACT SIGNAL
Prospective biomarker cohort evidence

First-trimester plasma asprosin and its association with gestational diabetes mellitus: A prospective cohort study

This prospective cohort enrolled 302 low-risk singleton pregnancies at 10–14 weeks, measured plasma asprosin, and assessed gestational diabetes at 24–28 weeks. Ninety-eight participants (32.5%) developed GDM. Asprosin varied with BMI but did not discriminate later GDM, with an AUC of 0.516. The study provides a first-trimester reference range and evidence against using this biomarker alone for early screening.

Thai researchersSathaphone Inthavong · Phudit Jatavan · Sirinart Kumfu · Nipon Chattipakorn · Theera Tongsong
Diabetes and Complications77IMPACT SIGNAL
Local case-control evidence

Factors associated with microvascular complications in patients with type 2 diabetes in Mueang District, Phitsanulok Province

A hospital-based case-control study in Mueang Phitsanulok compared 130 patients with physician-diagnosed microvascular complications and 260 controls. Diabetes for at least seven years, blood pressure of 140/90 mmHg or higher and high stress were associated with complications. The extremely large association for no metformin use had a very wide CI and cannot establish a direct protective drug effect.

Thai researchersNathamon Kamolvoradej · Patipat Vongruang · Sakesun Thongtip · Kongprai Tunsuchart
Mental Health and Family Caregiving85IMPACT SIGNAL
Instrument development and validation evidence

Psychometric Validation of a Family Adaptation Measure for First-Episode Psychosis

Researchers developed a culturally grounded measure of family adaptation and caregiving role engagement in Thai first-episode psychosis. Focus groups with 17 caregivers, item development and piloting preceded validation in 343 caregivers from four psychiatric hospitals, split into EFA (171) and CFA (172) groups. The 23-item, four-dimension FACRI explained 68.71% of variance and had overall Cronbach's alpha of 0.94. This is preliminary validity evidence, not a diagnostic test or proof of patient benefit.

Thai researchersWilai Napa · Nantiya Ekathikhomkit · Pennapa Unsanit · Patraporn Bhatarasakoon
Water, Sediment and the Mekong Basin77IMPACT SIGNAL
Catchment-scale modelling framework

A hydrological-year stratified regionalization framework for sediment rating curves in the largest tributary of the Mekong River

In the Mun River Basin, the Mekong's largest tributary, researchers developed a sediment-rating-curve regionalisation framework for sparse monitoring conditions. Flood, normal and drought years were separated before comparing regression and catchment-similarity approaches. Sediment-discharge behaviour varied by hydrological condition, while the preferred method depended on slope and erosion-related catchment attributes, arguing against a single static curve for every place and year.

Thai researchersNantawoot Inseeyong · Pavisorn Chuenchum · Kwanchai Pakoksung · Jeerapong Laonamsai
Malaria and Vaccine Development73IMPACT SIGNAL
Sequence and computational prediction evidence

Mapping HLA-restricted T-cell epitopes within conserved regions of Plasmodium vivax circumsporozoite protein from Thailand

PvCSP sequences from 34 P. vivax-infected patients in Southern Thailand were compared with 281 public sequences from Brazil and Vanuatu. IEDB predictions mapped T-cell epitopes against prevalent Thai HLA alleles. Conserved N- and C-terminal regions contained dense CD4+ and CD8+ targets, and cumulative modelled population coverage reached 95.86% in Southeast Asia. These are vaccine-design candidates, not observed immunogenicity or protection.

Thai researchersPongsakorn Thawornpan · Sasicha Suksapan · Thiranai Kitingen · Piyawan Kochayoo · Pachara Tianpothong · Patchanee Chootong
Crop Protection and Agricultural Bioproducts72IMPACT SIGNAL
Laboratory antagonism and preliminary toxicity evidence

Antagonistic Activity and Preliminary Toxicity Assessment of a Bacillus subtilis TU089 Bioproduct Against Phytophthora palmivora Causing Durian Root and Stem Rot

Five Bacillus strains were screened against Phytophthora palmivora MNP13, which causes durian root and stem rot. B. subtilis TU089 inhibited growth by 76.56±0.23% on plates and was developed into an encapsulated product at about 10^8 CFU/mL that retained activity comparable to fresh cells. Cell assays yielded IC10 values of 1,090 µg/mL in MRC-5 and 309.82 µg/mL in HaCaT cells; acute oral testing found no significant adverse effects under the studied conditions. Efficacy remains laboratory-based and safety preliminary.

Thai researchersPonchanok Datmanee · Apipu Ariyachayut · Thunyatorn Yimsoo · Dusit Athinuwat · Wilawan Chuaboon
Malaria and Adjunctive Treatment82IMPACT SIGNAL
Phase I safety and dose evidence

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial

A phase I trial in Kenyan and Zambian children hospitalised with severe malaria tested adjunctive sevuparin as three infusions at 0, 8 and 16 hours. Twenty-three children were enrolled and 20 were included in the primary analysis. Model-guided escalation and dose-limiting APTT prolongation led to a maximum tolerated dose of 3 mg/kg per infusion. This is an early safety and dose-finding result, not evidence of clinical efficacy.

Thai researchersNicholas P. J. Day · Arjen M. Dondorp
Air Pollution and Health85IMPACT SIGNAL
Provincial observational time-series evidence

Health risks and lag effects of ambient PM2.5 exposure on respiratory and cardiovascular mortality and morbidity in Ratchaburi, Thailand

Using a distributed lag non-linear model, the study linked ambient PM2.5 with respiratory and cardiovascular mortality and morbidity in Ratchaburi during 2015–2019, from the exposure day through seven subsequent days. Across all ages and genders, each 10 µg/m³ increase was associated with 5.42% higher respiratory mortality at lag 0 and 2.69% higher respiratory morbidity over lag 0–6.

Thai researchersSitthipong Pengjan · Sébastien Bonnet · Savitri Garivait
Maternal Health and High-Risk Pregnancy77IMPACT SIGNAL
Multi-hospital case-control evidence

Predictors of preeclampsia with severe features: A multi-center analysis of maternal and health system factors in Thai tertiary hospitals

Across four Thai tertiary hospitals, a case-control study compared 156 postpartum women with preeclampsia: 52 with and 104 without severe features, alongside data from 111 nurse-midwives. After adjustment for antenatal visits and gravidity, prior preeclampsia was associated with 5.99-fold higher odds of severe features. Moderate knowledge and higher BMI showed inverse associations, which should not be treated as causal protection.

Thai researchersTippawan Boonyaporn · Piyanun Limruangrong · Ameporn Ratinthorn · Thitipong Tankumpuan
Ethnic Health and Non-Communicable Disease81IMPACT SIGNAL
Grounded-theory qualitative evidence

Balancing tradition, modernity, and spirituality: A grounded theory of non-communicable disease management in the Tai Saek Ethnic Group of Thailand

A qualitative study of 18 Tai Saek adults from two Nakhon Phanom villages described NCD management as a non-linear negotiation among traditional lifeways, changing agriculture and diet, generational relations, spirituality and biomedicine. Participants did not simply reject modern care; they selectively combined ancestor worship with clinical treatment. This could support cultural empowerment, while heavy reliance on rituals could delay biomedical care.

Thai researchersAmornrat Sangsaikaew · Wasana Ruaisungnoen
Cancer Supportive Care89IMPACT SIGNAL
Mixed-methods evidence synthesis

Experiences and coping strategies among cancer patients with cancer-related cognitive impairment treated with chemotherapy: a mixed-methods systematic review

This mixed-methods systematic review synthesized 21 studies of chemotherapy-treated cancer patients with cancer-related cognitive impairment. Memory, concentration, and executive-function problems affected daily life, work, relationships, and emotions. Coping included memory aids, self-regulation, task modification, lifestyle changes, and social support. Perceived benefit is not trial-proven clinical efficacy.

Thai researchersJing Li · Wasana Ruaisungnoen · Supan Unjai · Parichat Wonggom
Environment and Risk Management89IMPACT SIGNAL
Regional model-validation evidence

The Socio-Economic Asymmetry Index (SEA): A Framework for Identifying Vulnerability–Exposure Mismatch in Flood-Prone Agricultural Landscapes

This study introduces the Socio-Economic Asymmetry Index (SEA) to identify agricultural areas where socioeconomic vulnerability outweighs physical flood exposure. The framework was tested at 63,010 sampling points in Thailand's Upper Chi River Basin using satellite and land-use data, six composite indices, Random Forest, and SHAP. About one quarter of the study area fell into high or very high asymmetry classes. The result is a spatial modelling tool for prioritising field assessment and support; it does not establish which factors causally produce flood losses.

Thai researchersPatiwat Littidej · Jiradech Majandang · Benjamabhorn Pumhirunroj
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
70IMPACT SIGNAL
Multidisciplinary

Diplommatina angulata Theobald & Stoliczka 1872

Open MIND

Thailand-affiliated authors
Piyoros Tongkerd · Arthit Pholyotha · Supunya Annate · Chirasak Sutcharit
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Clinical Medicine

From Biofortification to HT-29 Growth Inhibition: Selenium-Enriched Sunflower Sprouts Modulate Apoptosis- and Cell Cycle-Related Markers

Foods

Thailand-affiliated authors
Piyanete Chantiratikul · Anut Chantiratikul · Yada Laotongsan · Gondanai Lasungneon · Worachot Saengha · Thipphiya Karirat · Piyathida Promjamorn · Vijitra Luang‐In
Institutions
Mahasarakham University
70IMPACT SIGNAL
Clinical Medicine

Sustained reduction in blood culture utilization following a crisis-driven diagnostic stewardship intervention

Infection Control and Hospital Epidemiology

Thailand-affiliated authors
Alan E. Gross
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Multidisciplinary

Diplommatina tumida subsp. laisenensis Gude 1921

Open MIND

Thailand-affiliated authors
Piyoros Tongkerd · Arthit Pholyotha · Supunya Annate · Chirasak Sutcharit
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Multidisciplinary

Optimization of rosmarinic acid extraction from Thunbergia laurifolia leaves using a green solvent and evaluation of its biological activities

Scientific Reports

Thailand-affiliated authors
Kotchaphan Chooluck · Amaraporn Wongrakpanich · Warisara Parichatikanond · Brompoj Prutthiwanasan · Naphatson Chanthathamrongsiri
Institutions
Mahidol University · Burapha University
70IMPACT SIGNAL
Engineering

Fragility-based seismic evaluation and GFRP retrofitting of short-span bridge piers in Thailand’s seismic zones

Results in Engineering

Thailand-affiliated authors
Phoonsak Pheinsusom · Chayut Ngamkhanong · Panon Latcharote · Qudeer Hussain · Chatpan Chintanapakdee · Tidarut Jirawattanasomkul · Tamon Ueda
Institutions
Chulalongkorn University · Mahidol University
70IMPACT SIGNAL
Environmental Engineering

Interfacial Ligand Density Regulates Solvent-Induced Phase Transformation in CsPbBr 3 /Cs 4 PbBr 6 Nanocrystals

Chemistry of Materials

Thailand-affiliated authors
Tetsuya Kida
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Clinical Medicine

Risk assessment of subclinical mastitis in Holstein cows in Jiangsu Province of China

Frontiers in Veterinary Science

Thailand-affiliated authors
Niel A. Karrow
Institutions
Department of Livestock Development
70IMPACT SIGNAL
Global Public Health

The PAU Survey: Uncovering the connection between intrinsic and observed galaxy properties using symbolic regression

Monthly Notices of the Royal Astronomical Society

Thailand-affiliated authors
Suttikoon Koonkor
Institutions
National Astronomical Research Institute of Thailand
70IMPACT SIGNAL
Clinical Medicine

Effect of Titanium Dioxide Nanoparticle-Reinforced Silicone Elastomers on Candida albicans Adhesion

European Journal of Dentistry

Thailand-affiliated authors
Sasiwimol Sanohkan · Kemarajt Kemavongse
Institutions
Prince of Songkla University
70IMPACT SIGNAL
Clinical Medicine

Intravascular behavior of cutaneous polynucleotide injectables following intra-arterial exposure

Scientific Reports

Thailand-affiliated authors
Suphagan Boonpethkaew · Atchima Suwanchinda · Werayut Yingmema · Wilai Thanasarnaksorn
Institutions
Thammasat University · Mahidol University · Ramathibodi Hospital · Rangsit University
70IMPACT SIGNAL
Clinical Medicine

Novel CHD7 Variants Associated with an Expanded Orofacial and Dental Phenotype

European Journal of Dentistry

Thailand-affiliated authors
Wuttichart Kamolvisit · Thantrira Porntaveetus · Tanit Arunratanothai · Thanakorn Theerapanon · Atsushi Ohazama · Sunisa Rochanavibhata · Risa Chaisuparat · Chanatjit Cheawsamoot · Aayalida Buasong · Rungroj Thangpong · Phawin Kor-anantakul · Vorasuk Shotelersuk
Institutions
Thai Red Cross Society · Chulalongkorn University · King Chulalongkorn Memorial Hospital
70IMPACT SIGNAL
Multidisciplinary

Structure and dynamics of a four-protofilament microtubule from Heimdallarchaeales α/β-tubulin

Science Advances

Thailand-affiliated authors
Robert C. Robinson
Institutions
Vidyasirimedhi Institute of Science and Technology
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link