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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
HIV, Ageing and Metabolic Health89IMPACT SIGNAL
Longitudinal observational cohort evidence

Metabolic Dysfunction‐Associated Steatohepatitis and the Progression of Cognitive Decline in Older Thai People With HIV

This prospective HIV-NAT cohort in Bangkok followed 291 people with HIV aged at least 50 years from 2015–2024; 60 participants, or 20.6%, met non-invasive criteria for MASH at baseline. Over a median 5.9 years, baseline MASH was associated with steeper decline in Thai-validated MoCA scores after adjustment for multiple metabolic, social, and HIV-related factors, whereas MASLD without the MASH signal was not associated with decline. The findings support integrated liver and cognitive surveillance but do not show that treating MASH prevents cognitive deterioration.

Thai researchersKatekarn Porkaew · Akarin Hiransuthikul · Win Min Han · Tanakorn Apornpong · Sasiwimol Ubolyam · Stephen John Kerr · Anchalee Avihingsanon
Sports Science and Youth Development88IMPACT SIGNAL
Exploratory cross-sectional evidence

Early neuromuscular and cognitive signatures in high-performance young male Muay Thai athletes

Researchers assessed 215 high-performance male Muay Thai athletes aged 8–18 over five days and compared four age groups. Anthropometry, biological maturation, maximal strength, and several cognitive measures improved with age, while limb asymmetry, fatigue indices, Nordic hamstring performance, lower-limb dynamic strength index, and upper-limb push-up force did not differ by age. PCA suggested age-specific multidimensional profiles, but cross-sectional data do not prove an effect of age or training and do not constitute a validated talent-selection model.

Thai researchersPhornpot Chainok · Naruepon Vongjaturapat · Nattasit Suwannawat · Atcharat Yongtawee
Patient-Reported Outcome Measurement86IMPACT SIGNAL
Qualitative evidence from patient experience

Measuring what matters: Evaluating quality of life instruments through the eyes of people with Parkinson's disease

Researchers asked 31 people living with Parkinson's disease to complete eight quality-of-life instruments and then used semi-structured interviews to explore what helped or hindered meaningful reporting. Participants favored broad response options, attention to personal, emotional, and practical effects, clear and specific language, and a balance of positive and negative questions. The study centers lived experience in instrument refinement but does not establish which questionnaire has the best validity, reliability, or responsiveness.

Thai researchersOnanong Phokaewvarangkul
Business, Marketing and Consumer Behaviour86IMPACT SIGNAL
Survey and configurational-model evidence

Balancing continuity and relevance: Innovation-nostalgia configurations in time-honored brand revitalization

Revitalizing a time-honored brand requires continuity of identity alongside present-day relevance. The study analyzed 404 firm-side respondents from 76 enterprises and 536 consumers in Southwestern China using PLS-SEM and fsQCA. Innovation and nostalgia interacted positively only in the firm model; both were positively associated on the consumer side, where nostalgia was stronger. Set-theoretic analysis identified overlapping configurations and three balancing logics, framing revitalization as a multi-actor process rather than a universal formula.

Thai researchersXiangyu Li · Danaikrit Inthurit · Surachai Kungwon · Nirote Sinnarong
Sustainable Tourism and Climate Risk85IMPACT SIGNAL
Cross-sectional structural and configurational evidence

Revisit Intention Under Climate Risk in Island Tourism: Structural and Configurational Evidence from PLS-SEM and fsQCA

The study examines how perceived island-climate risk, destination climate resilience, tourism climate-service usefulness, and destination trust combine in relation to intention to revisit Phuket. An on-site survey of 480 Chinese tourists was analyzed using both PLS-SEM and fsQCA. The structural model explained 74.6% of variance in revisit intention: perceived climate risk was negatively associated, the other three constructs were positively associated, and trust had the strongest direct association. The configurational analysis identified multiple routes to high and low intention. All results concern cross-sectional self-reported intention, not proof that an intervention causes actual return travel.

Thai researchersXinda Yang · Sirichai Preudhikulpradab · Lalida Arphawatthanasakul
Health Professions Education and Research Equity85IMPACT SIGNAL
Global bibliometric and network analysis

Moving towards decolonizing health professions education research: an analysis of global network patterns and equity implications

An all-Thai team analyzed co-authorship structures in five leading Q1 health-professions-education journals from 2015 through 2024, covering 13,187 publications, 45,366 authors, and affiliations in 162 countries. Annual output grew 2.7-fold and distinct authors 3.7-fold. High-income-country-only publications fell from 86% to 63%, while non-high-income-only publications rose from 6% to 26%. The network became broader and more connected, yet the United States, United Kingdom, and Canada remained central, and low-income-country collaboration was more often routed through high-income partners than through regionally led networks.

Thai researchersPeerasit Sitthirat · Seksan Yoadsanit · Phuphinyo Limchantra · Kanjaree Suppawittaya · Suttithan Suwannoppakun · Piwat Suppawittaya · Phanuwich Kaewkamjornchai · Somsak Chunharas
Healthcare Operations and Decision Support85IMPACT SIGNAL
Computational simulation evidence

An Integrated Intelligent Decision Support System Combining Stochastic Programming and Queuing Theory for Dynamic Triage of Surgical Critical Care Patients to Prevent Postoperative Complications in Healthcare Business Operation

The authors developed SQDSS, combining two-stage stochastic programming with multi-class priority queueing to triage surgical critical-care patients under uncertain arrivals, changing acuity, and deterioration while waiting. Across 48 synthetic datasets, comparisons with first-come-first-served and a fixed-severity rule showed about 22.8% shorter high-acuity waits, 16% greater bed utilization, roughly 28% less queue overflow, and roughly 18% fewer simulated complications. Benefits were greatest under surge and trauma-dominant conditions. No real-patient data or implementation trial were used, so these results demonstrate modeled feasibility rather than clinical effectiveness.

Thai researchersJarun Bootdachi · Parichat Wonggom · Wiphawadee Potisopha
Adolescent Mental Health and Measurement85IMPACT SIGNAL
Psychometric validation

Psychometric Properties of the Revised Thai Rosenberg Self-Esteem Scale (r-TRSES) in Adolescents: Confirmatory Factor Analysis and Rasch Modeling

The study evaluates a culturally reworded Thai Rosenberg Self-Esteem Scale in 443 boarding-school students. Confirmatory factor analysis supported a bifactor structure with a dominant general self-esteem factor and residual wording-related variance. Rasch analysis supported essential unidimensionality, acceptable item fit, strong reliability, and ordered response thresholds. No item exceeded the prespecified threshold for sex differential item functioning. Scores correlated positively with resilience (r=0.589) and negatively with depressive symptoms (r=-0.601), but precision declined among adolescents with higher self-esteem and broader replication remains necessary.

Thai researchersJustin DeMaranville · Peerapat Naprung · Supisara Prompila · Nahathai Wongpakaran · Tinakon Wongpakaran
Clinical-Trial Systems and Research Capacity88IMPACT SIGNAL
Expert-workshop open letter; version 1 awaiting peer review

Strengthening Sustainable Clinical Trial Models for Greater Health Impact: Expert Discussion from the Annual Wellcome Major International Programme Regional Meeting 2024

This open letter synthesizes the 2024 Wellcome Major International Programmes meeting, which brought together research-institution representatives from Africa, Asia, and the United Kingdom. Participants identified limited clinical-trial literacy, unstable funding, workforce recruitment and retention, inequitable partnerships, ethics and regulatory bottlenecks, operational inefficiencies, and barriers in remote settings. Proposed responses included locally led agendas, diversified funding, workforce development, stronger community and regulator engagement, platform, adaptive and decentralized trials, shared monitoring, and interoperable data systems. The meeting agreed to explore a formal MIPs alliance, but the paper does not show that the alliance has yet delivered operational or health outcomes.

Thai researchersNicholas P J Day · Nicholas J White
Generative AI and Higher Education85IMPACT SIGNAL
Cross-sectional PLS-SEM evidence

Extending UTAUT with Metacognition and Self-Regulation: Evidence on Generative AI Use among University Students

A survey of 451 students at seven Thai Rajabhat universities extended UTAUT by positioning metacognitive awareness and self-regulated learning between technology-acceptance determinants and GenAI-use intention, with intention predicting self-reported use of GenAI as a cognitive partner. Facilitating conditions had the strongest associations with metacognition and self-regulation but no significant direct association with intention; the significant indirect path ran through metacognition. Social influence was the strongest direct predictor of intention, followed by metacognition, while effort expectancy and self-regulated learning did not predict intention in this model.

Thai researchersNatthawan Phoonson · Thada Jantakoon · Rukthin Laoha
Geriatric and Transitional Care85IMPACT SIGNAL
Prospective observational evidence

Nearly Two-Thirds of Frail Older Adults Had an Unplanned Hospital Return Within Six Months

An interim prospective secondary analysis from a parent trial at one university hospital followed 170 frail older adults after medical-ward discharge. A broad composite of emergency visits, unplanned outpatient visits, and readmissions rose from 34.7% at one month to 64.7% at six months. Better nutritional status was associated with lower return odds, and returners had higher direct medical costs. The observational analysis does not show that nutritional intervention prevents return.

Thai researchersPatumporn Suraarunsumrit · Maytinee Srisubin · Sutisa Pitiyarn · Ponnapa Petchthai · Dariya Tantiameorn · Chaloemphon Thedpun · Sunit Jarungjitaree · Kotchamon Sukyoyot · Unchana Sura-amonrattana · Varalak Srinonprasert · Titima Wongviriyawong
HIV Prevention and Health Equity92IMPACT SIGNAL
Cross-national cross-sectional evidence

PrEP Use and Willingness Cascades Among Transgender Women in 11 Asian Countries: Findings From the PrEP APPEAL Cross-Sectional Online Survey

The 2022 PrEP APPEAL online survey included 1,178 transgender women in 11 Asian countries. Awareness was 80.0%; among those aware, 62.6% had ever used PrEP, and 78.1% of ever-users were current users. Among higher-risk PrEP-naïve respondents, 60.0% were willing to use it, but only 34.0% of those willing would pay. Healthcare discrimination was associated with lower lifetime use; causality cannot be inferred.

Thai researchersRena Janamnuaysook · Hua Boonyapisomparn · Nittaya Phanuphak
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Diagnostic accuracy of a clinical score with a rapid diagnostic test for enteric fever in Nepal, Bangladesh and Cambodia

BMC Infectious Diseases

Thailand-affiliated authors
Nicholas P.J. Day · Arjen Dondorp
Institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Shared and Distinct T-Cell Receptor Characteristics of CD4+ and CD8+ Drug-Specific T-Cells In Vitro Generated from Healthy Donors and Hypersensitive Patients

Chemical Research in Toxicology

Thailand-affiliated authors
Kanoot Jaruthamsophon · Jirawat Pratoomwun · Antida Sangiemchoey · Araya Yeunyongviwat · Kanitpong Phabphal · Chonlaphat Sukasem
Institutions
Prince of Songkla University · Huachiew Chalermprakiet University · Mahidol University · Ramathibodi Hospital · Burapha University
77IMPACT SIGNAL
Clinical Medicine

Localization of feline gammaherpesvirus 1 in lymphoid tissues and pulmonary fibrotic lesions of naturally infected cats

Veterinary Pathology

Thailand-affiliated authors
Chutchai Piewbang · Magdalena Novia Devina Putri · Aisyah Nikmatuz Zahro · Panitnan Punyathi · Sitthichok Lacharoje · Somporn Techangamsuwan
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Clinical features associated with autism spectrum disorder diagnosed before 30 months of age: evidence from tertiary care hospitals in Thailand

International Journal of Developmental Disabilities

Thailand-affiliated authors
Anya Laopongsit · Nontiya Homkham · Pimwarat Srikummoon · Kamonrut Koobubpha · Patrinee Traisathit
Institutions
Chiang Rai Rajabhat University · Thammasat University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Rapid Gel-Based Recombinase Polymerase Amplification Assay for Detection and Sequence Confirmation of Ehrlichia canis

Animals

Thailand-affiliated authors
Peeravit Sumpavong · Kitjawan Khumtub · Krittanut Kanittakul · Sarawan Kaewmongkol · Gunn Kaewmongkol
Institutions
Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Synchronous B-lymphoblastic leukemia/lymphoma and subcutaneous panniculitis-like T-cell lymphoma in an 11-year-old pediatric patient

BMC Pediatrics

Thailand-affiliated authors
Phuphinyo Limchantra · Jirat Temsangsukmanee · Suradej Hongeng · Kran Suknuntha
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

A Decade of Croup Management: Guideline Adherence, Practice Variation, and Opportunities for Improvement

Children

Thailand-affiliated authors
Jirattikarn Jirawong · Wanaporn Anuntaseree · Kanokpan Ruangnapa · Kantara Saelim · Pharsai Prasertsan
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Cloud-Based Deep Learning for Multi-Class Dermatological Screening: An Empirical Study Using Pretrained CNNs

Sci

Thailand-affiliated authors
Theetach Rabablert · Amonnat Kaewnok · Chitnarong Sirisathitkul · Yaowarat Sirisathitkul
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

Molecular Characteristics and Factors Associated with Antimicrobial Resistance in Campylobacter Isolates from Small-Scale Chicken Farms in Southern Thailand

Antibiotics

Thailand-affiliated authors
Nguyễn Thị Mỹ Nhân · Phitchayapak Wintachai · Thotsapol Thomrongsuwannakij
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

PARP inhibition induces a redox-dependent dormant reservoir vulnerable to disulfiram in high-grade serous ovarian cancer

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Sutthipun Suriya · Supawan Jamnongsong · Chanettee Jamyuang · Suwanit Therasakvichya · Somponnat Sampattavanich
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Digital Health

Electroencephalography-Based Emotion Recognition Using Auditory Stimulation for Affective Brain–Computer Interfaces

Sensors

Thailand-affiliated authors
Charoenporn Bouyam · Nannaphat Siribunyaphat · Yunyong Punsawad
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

KK12, a novel anticancer peptide, induces apoptosis in human lung cancer A549 cells

Scientific Reports

Thailand-affiliated authors
Jantana Yahuafai · Prayumat Onsrisawat · Ratasark Summart · Mariena Ketudat-Cairns · Thippawan Pimchan · Jirawat Yongsawatdigul · Natteewan Udomsil
Institutions
National Cancer Institute of Thailand · Kanchanaburi Rajabhat University · Mahidol University · Suranaree University of Technology
77IMPACT SIGNAL
Clinical Medicine

Limitations of NEWS2 for predicting 48-hour emergency department revisits: a real-world retrospective cohort study

International Journal of Emergency Medicine

Thailand-affiliated authors
Sarunpakorn Permpatdechakul · Theerapon Tangsuwanaruk · Borwon Wittayachamnankul · Pavita Laohakul · Chanon Changratanakorn · Boriboon Chenthanakij
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Efficacy of mucoadhesive nanoemulsion-based immersion vaccine against Streptococcus agalactiae and Edwardsiella tarda infections in Nile tilapia (Oreochromis niloticus)

Aquaculture Reports

Thailand-affiliated authors
Benchawan Kumwan · Pakapon Meachasompop · Yosapon Adisornprasert · Jitraporn Phaksopa · Wararut Buncharoen · Patcharapong Thangsunan · Pattanapong Thangsunan · Prapansak Srisapoome · Channarong Rodkhum · Natthapong Paankhao · Anurak Uchuwittayakul
Institutions
Kasetsart University · Chiang Mai University · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Dietary Application of Synergistically Degraded Low-Molecular-Weight Chitosan to Promote Health and Antioxidant Responses in Pacific White Shrimp (Litopenaeus vannamei)

Antioxidants

Thailand-affiliated authors
Natthapong Paankhao · Wararut Buncharoen · Benchawan Kumwan · Pakapon Meachasompop · Yosapon Adisornprasert · Chonlatat Rajitdumrong · Pimrawee Chaemlek · Prapansak Srisapoome · Passakorn Kingwascharapong · Anurak Uchuwittayakul
Institutions
Kasetsart University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Purifying Selection and Interspecific Differentiation at the Myf5 Locus Inform Hybrid Identification and Genetic Management of Thai Clariid Resources

Genes

Thailand-affiliated authors
Phonemany Thammachak · Ton Huu Duc Nguyen · Rinrapat Nitipatpornpanya · Anh Huynh Luu · Edem Uduak Linus · Thitipong Panthum · Kednapat Sriphairoj · Sittichai Hatachote · Satid Chatchaiphan · Chaiwut Grudpan · Jarungjit Grudpan · S. Kiriratnikom · Jiraboon Prasanpan · Orathai Sawatdichaikul · Worapong Singchat · Kornsorn Srikulnath
Institutions
Kasetsart University · Sakon Nakhon Rajabhat University · Ubon Ratchathani University · Thaksin University · Kalasin University
77IMPACT SIGNAL
Clinical Medicine

Long-acting reversible contraceptive use in postpartum and postabortion adolescents: initiation, predictors, and continuation outcomes

Reproductive Health

Thailand-affiliated authors
Paparnin Sangvornrungsie · Nalinee Panichyawat · Thanyarat Wongwananuruk · Nichamon Parkpinyo · Julaporn Pooliam · Marisa Vongsiri · Jaratporn Inthawong
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Proteomic Analysis of Urinary Extracellular Vesicles Reveals Estrogen/Progesterone Status-Associated Biomarkers of Breast Cancer Patients: Potential Roles in Diagnosis and Prognosis

Journal of Health Science and Medical Research

Thailand-affiliated authors
Rassanee Bissanum · Nilobon Jeanmard · Hutcha Sriplung · Sawanya Charoenlappanit · Sittiruk Roytrakul · Raphatphorn Navakanitworakul
Institutions
Prince of Songkla University · National Science and Technology Development Agency
77IMPACT SIGNAL
Clinical Medicine

New Host and Geographic Records of Epifoliar Fungi on Cinnamomum loureiroi from Thailand

Phytotaxa

Thailand-affiliated authors
Asieh Vasighzadeh · Alireza Armand · Ruvishika S. Jayawardena · Kevin D. Hyde
Institutions
Mae Fah Luang University
77IMPACT SIGNAL
Clinical Medicine

Organization of the Digestive Tract and Localization of Protein Fibre in Electrophorus sp. (Gymnotiformes: Gymnotidae)

Acta Zoologica

Thailand-affiliated authors
Sinlapachai Senarat · Narit Thaochan · Kitiya Kongthong · Peerapon Sornying · Piyakorn Boonyoung
Institutions
Prince of Songkla University · Naresuan University
77IMPACT SIGNAL
Clinical Medicine

Multi-Targeted Neuroprotection by Areca catechu Against Cisplatin-Induced Neurotoxicity: Cellular, Caenorhabditis elegans, and Metabolomic Evidence

International Journal of Molecular Sciences

Thailand-affiliated authors
Kishoree Krishna Kumaree · Clerance Su Yee Cheong · Kanika Verma · Kartina Nadyani · Nureesun Mahamud · Pornpimol Mahamad · Tewin Tencomnao · Anchalee Prasansuklab · James Michael Brimson
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Investigation of Cytokine Profiles, the Expression of Genes Involved in Somatic Hypermutation and Peripheral Tolerance, and Their Correlation with Autoantibody Levels in Northern-Thai Immunodeficient Patients Carrying Anti-Interferon-γ Autoantibodies

International Journal of Molecular Sciences

Thailand-affiliated authors
Kritsadee Rattanathammethee · Kriangkrai Chawansuntati · Nongkran Lumjuan · Nattaya Nusartsang · Romanee Chaiwarith · Jutarat Praparattanapan · Khuanchai Supparatpinyo · Jiraprapa Wipasa
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Real-world evidence on off-label underdosing of direct oral anticoagulants in Asian patients with atrial fibrillation: prescribing patterns, determinants, and outcomes

Future Science OA

Thailand-affiliated authors
Supisara Pholprasittito · Supharat Wattanasombat · Natrawee Bureekam
Institutions
Lampang Hospital · ChiangRai Prachanukroh Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link