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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
Rational Prescribing and Medication Safety74IMPACT SIGNAL
Evidence of global relevance

Assessment of Inappropriate Omeprazole Prescribing, Associated Factors and Financial Impact in the Outpatient Department of a General Hospital in Thailand

A review of 347 outpatient prescriptions for 229 patients from January-June 2025 at one Thai general hospital classified 58.2% of omeprazole prescriptions as potentially inappropriate. Of these, 75.2% lacked an appropriate indication, followed by inappropriate duration.

Thai researchersSaranporn Srithonrat · Chayanat Pongsathabordee · Satawat Kulworahathai · Chidawan Prapat · Aticha Jamratkittiwan · Nichakan Jitakson · Taniya Paiboonvong
Endocrine Emergency Medicine74IMPACT SIGNAL
Evidence of global relevance

Prognostic factors and prognostic risk score of 30-day all-cause mortality in thyroid storm

A retrospective cohort of 115 thyroid-storm patients at a Thai tertiary center had 13% 30-day mortality. An eight-point score using male sex, hypertension, SOFA at least 2, and GCS at most 10 achieved apparent AUC 0.81 and bootstrap-corrected AUC 0.79.

Thai researchersPakpoom Chantrapitak · Worapaka Manosroi · Sittikul Thipbumrung · Pichitchai Atthakomol
Companion-Animal AMR and One Health74IMPACT SIGNAL
Evidence of global relevance

Genomic Characterization, Antimicrobial Resistance Profiles, and tetA Nucleotide Substitutions of Escherichia coli Isolated from Healthy Dogs in Thailand

Fecal samples from 200 healthy dogs at 50 clinics in Chiang Mai and Nakhon Si Thammarat during January-March 2026 yielded 66 E. coli isolates. Resistance reached 100% for ampicillin, 84.85% for piperacillin, 60.61% for ceftriaxone, 56.06% for tetracycline, and 47% multidrug resistance.

Thai researchersRavisa Warin · Naparat Suttidate · Wanna Suriyasathaporn · Witaya Suriyasathaporn · Ratchadaporn Boripun
Microalgae and Energy Harvesting74IMPACT SIGNAL
Evidence of global relevance

Immobilized microalgae-driven triboelectric nanogenerators for sustainable bioelectricity production

Thai researchers immobilized living Chlorella vulgaris TISTR 8580 at different densities on aluminum electrodes as a triboelectric layer for solid-solid and solid-liquid interactions, reporting peak output of 110 V and 330 nA.

Thai researchersChalampol Janpum · Tanakit Komkhum · Naratip Vittayakorn · Kamon Thinsurat · Chawalit Ngamcharussrivichai · Pichaya In-na
Alternative Proteins, Drying, and Flavor73IMPACT SIGNAL
Evidence of global relevance

Drying-Induced Structural and Oxidative Transformations in Sustainable Proteins: Impact on Physicochemical Properties and Flavor-Binding Functionality

This review proposes a structure-process-function framework explaining how hot-air, heat-pump, microwave, and freeze-drying differently unfold, aggregate, and oxidize plant and marine proteins, changing how volatile flavors are bound, retained, and released.

Thai researchersYoon Hlaine Barani · Passakorn Kingwascharapong · Saroat Rawdkuen
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
74IMPACT SIGNAL
Environmental Engineering

Study on Compressive Strength, Flexural Behavior, and Chloride Penetration of Steel Fiber Reinforced Concrete (SFRC) under Chloride Environment

The Journal of King Mongkut s University of Technology North Bangkok

Thailand-affiliated authors
Thanapol Yanweerasak · Porjan Tuttipongsawat · Burachat Kittikornjarus
Institutions
Burapha University · Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Biosafety of rabies virus and related lyssaviruses: Risks, precautions, and knowledge gaps in diagnostic and research laboratories

PLoS neglected tropical diseases

Thailand-affiliated authors
Stuart Dean Blacksell · Khanh Kim Le
Institutions
Mahidol University
74IMPACT SIGNAL
Engineering

Physicochemical and microbiological qualities of shrimp (Litopenaeus vannamei) coated with pectin incorporated with green tea spent extract during refrigerated storage

Journal of Food Composition and Analysis

Thailand-affiliated authors
Nilesh Prakash Nirmal · Arthittaya Thuanthong · Anantita Sangsuriyawong · Zain ul Abideen
Institutions
Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Efficacy of 7% Ectoine Cream for Facial Seborrheic Dermatitis: A Randomized Controlled Trial of Acute and Maintenance Phases

Cosmetics

Thailand-affiliated authors
Nirynya Jitarayameth · Nanticha Kamanamool · Chotinij Lertphanichkul · Chantalck Muennarong · Montree Udompataikul
Institutions
Srinakharinwirot University
74IMPACT SIGNAL
Clinical Medicine

Ventilator-dependent unit as a specialized weaning unit in a resource-limited setting: Evidence review, implementation framework and clinical outcome

Clinical Critical Care

Thailand-affiliated authors
Rathasart Pengpu · Atikun Limsukon · Juthamas Inchai · Tula Wongpalee · Konlawij Trongtrakul
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Trade-Offs in Growth Performance, Serum Biochemistry, and Fillet Amino Acid Profiles of Red Tilapia Fed Graded Levels of Azolla microphylla Meal in a Fishmeal Replacement Blend, with Exploratory Observations on Intestinal Microbiota

Veterinary Sciences

Thailand-affiliated authors
Panitnart Auputinan · Nantapong Sumket · Somchart Tana · Payungsuk Intawicha · Phanit Srisuttha · Phadungnaree Saenmuang · Sontaya Sookying · Dutrudi Panprommin · Paiboon Panase
Institutions
University of Phayao
74IMPACT SIGNAL
Energy and Materials

Development and Field Validation of a Solar-Powered Smart Buoy for Saltwater Intrusion Monitoring

Solar

Thailand-affiliated authors
Wirote Ritthong · Kittigorn Chalernphon · Nutthapong Kunla · Pongthep Poungthong · Naphat Albutt · Akom Boonpunya · Khongdet Phasinam
Institutions
Shinawatra University · Pathumthani University · Bangkokthonburi University · King Mongkut's Institute of Technology Ladkrabang
74IMPACT SIGNAL
Clinical Medicine

A Bioactive Microbial Extract from Priestia aryabhattai PTKU-123 Suppresses Phytophthora palmivora Disease and Reprograms Defense-Associated Metabolism in Durian Seedlings

Sci

Thailand-affiliated authors
Nattawut Chaloeykram · Chutirat Ongputhza · Phatlada Saengsurin · Punyaphat Bunroengsak · Arisara Thongpech · Nisit Watthanasakphuban · Siam Popluechai · Sumallika Morakul · Nattakorn Kuncharoen · Paiboon Tunsagool
Institutions
Kasetsart University · Mae Fah Luang University
74IMPACT SIGNAL
Clinical Medicine

Clinical outcomes of different preoperative treatment approaches in locally advanced rectal cancer: real-world experience

BMC Cancer

Thailand-affiliated authors
Jitlada Khonglim · Napat Angkathunyakul · Ananya Pongpaibul · Janjira Petsuksiri · Vutisiri Veerasarn · Woramin Riansuwan · Vitoon Chinswangwatanakul · Charuwan Akewanlop · Krittiya Korphaisarn
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Analysis of Factors Affecting Consultation-to-Puncture Time in Patients with Acute Ischemic Stroke within a Metropolitan Hospital Referral Network: A Retrospective Cohort Study

Asian Journal of Neurosurgery

Thailand-affiliated authors
Ittichai Sakarunchai · Peerawas Santheerapharp · Potchara Veerarattakul · Chabarprai Tonglor
Institutions
Bangkok Metropolitan Administration
74IMPACT SIGNAL
Clinical Medicine

Functional alterations of neutrophils from β-thalassemia patients exposed to Pythium insidiosum: An ex vivo study

PLoS ONE

Thailand-affiliated authors
Pasinee Sangsiwarit · Wisitsak Phoksawat · Nattiya Teawtrakul · Sonwit Phanabamrung · Parama Budmala · Ariya Chindamporn · Pratsanee Hiengrach
Institutions
Khon Kaen University · Srinagarind Hospital, Faculty of Medicine, Khon Kaen University · Chulalongkorn University
74IMPACT SIGNAL
Environmental Engineering

Characterization and biodegradation of polyhydroxyalkanoates (PHAs) in a simulated marine environment

Scientific Reports

Thailand-affiliated authors
Piyawan Kunriya · Pilanee Vaithanomsat · Antika Boondaeng · Wachirah Jaingam · Chanaporn Trakunjae
Institutions
Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Chemical and Proteomic Characterization of Bioactive Protein-Enriched Fraction from Schizophyllum commune with Anticancer Activity in HeLa Cells

ACS Omega

Thailand-affiliated authors
Saranya Sedtananun · Lueacha Tabtimmai · Chanapat Butsukon · Chanikan Sonklin · Kiattawee Choowongkomon
Institutions
King Mongkut's University of Technology North Bangkok · Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Mucoadhesive Chitosome-Based Buccal Delivery of Goat Placenta-Derived Bioactive Macromolecules: Effects on 5-Fluorouracil-Induced Gingival Fibroblast Injury

Pharmaceutics

Thailand-affiliated authors
Worranan Rangsimawong · Phaijit Sritananuwat · Sureewan Duangjit · Natawat Chankana · Praneet Opanasopit
Institutions
Ratchathani University · Ubon Ratchathani University · Rangsit University · Silpakorn University
74IMPACT SIGNAL
Clinical Medicine

Integrated microfluidic platform for continuous downstream purification and in-line residual ethanol monitoring of exosome-mimetic nanoparticles

Sensors and Actuators B Chemical

Thailand-affiliated authors
Vasita Lapee-e · Abdulhadee Yakoh · Hyo‐Il Jung
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Cytotoxicity, antibacterial efficacy, and fluoride content of commercial herbal toothpastes

BDJ Open

Thailand-affiliated authors
Nuttanun Poeaim · Pasiree Thongthai · Pimduean Sivavong · Phakvalunch Rujiraprasert · Thanaphum Noom Osathanon · Thawanrat Singthong · Budsaraporn Boonsuth · Dusit Nantanapiboon
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Sertoli cell tumor in a boar: Pathological and immunohistochemical comparison with canine cases

The Thai Journal of Veterinary Medicine

Thailand-affiliated authors
Anurak Tibboo · Hataitip Changchum · Nuttiya Saengrueng · Panvard Unjai · Natchanon Dumniem · Kasem Rattanapinyopituk · Komkrich Teankum
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Supercharged Colonic Interposition for Total Oesophageal Reconstruction: Technical Refinements, Perioperative Protocol, and Functional Outcomes

Siriraj Medical Journal/San Sirirat

Thailand-affiliated authors
Sarut Chaisrisawadisuk · Pornchanit Karanthakarn · Sirin Apichonbancha · Nutcha Yodrabum · Jirawat Swangsri
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Engineering

Efficacy of Fluoride Toothpaste Fortified With Micro‐ and Nano‐Hydroxyapatite on Remineralization and Surface Roughness of Synthetic Enamel

Clinical and Experimental Dental Research

Thailand-affiliated authors
Porawit Kamnoedboon · Phakvalunch Rujiraprasert · Thawanrat Singthong · Thanaphum Noom Osathanon · Chalermkwan Makornpan · Chawalid Pianmee · Naruporn Monmaturapoj · Dusit Nantanapiboon
Institutions
Chulalongkorn University · National Science and Technology Development Agency · Thailand National Metal and Materials Technology Center · Surin Hospital
74IMPACT SIGNAL
Clinical Medicine

Associations of Maximal Inspiratory Pressure With Lung Hyperinflation, Functional Capacity, and Muscle Strength in Patients With Chronic Obstructive Pulmonary Disease

Physiotherapy Research International

Thailand-affiliated authors
Jarinya Kraisalee · Warawut Chaiwong · Teelek Lungta · Nutcha Vimolsutjarit · Mujalin Prasannarong · Athavudh Deesomchok · Sauwaluk Dacha
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Longitudinal Changes in Cervical Length Prior to the Onset of Spontaneous Labor at Term Gestation

AJOG Global Reports

Thailand-affiliated authors
Puntabut Warintaksa · Supakorn Chaiyakarn · Maolee Bhuwapathanapun · Chalongraj Ratanawongsaroj · Orathai Munggaranonchai · Sasivimol Rattanasiri · Piya Chaemsaithong
Institutions
Mahidol University · Ramathibodi Hospital · Phramongkutklao Hospital
74IMPACT SIGNAL
Clinical Medicine

Development and Internal Validation of the Si-AAA Prognostic Score for Five-Year Overall Survival after Endovascular Aneurysm Repair in Patients with Asymptomatic Abdominal Aortic Aneurysm

Annals of Vascular Surgery

Thailand-affiliated authors
Tossapol Prapassaro · Natwadee Jitcharoen · Khamin Chinsakchai · Sasima Tongsai · Kiattisak Hongku · Chumpol Wongwanit · Nuttawut Sermsathanasawadi · Suteekhanit Hahtapornsawan · Nattawut Puangpunngam · Kanin Pruekprasert · Tiwa Chaisongrit · Chanean Ruangsetakit
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Environmental Engineering

A Novel Indoor Environmental Quality Assessment Method for Vernacular Bamboo Houses in Tropical Climates

Emerging Science Journal

Thailand-affiliated authors
Romrawee Srithongkaew · Kantaphong Srimuang · Wirut Thinnakorn
Institutions
Walailak University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link