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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Impact of biofilm formation on mortality in Candida tropicalis candidaemia: A retrospective study of ICU and Non-ICU patients

A retrospective Thai referral-center study of 146 C. tropicalis candidemia episodes in 145 patients found high biofilm formation in 33.6% and 30-day mortality of 74.0%. Overall mortality did not differ by biofilm category; lower survival only in non-ICU patients is a subgroup finding requiring confirmation, not a stand-alone prognostic marker.

Thai researchersTeera Leepattarakit · Orawan Tulyaprawat · Anusara Mongkudkarn · Popchai Ngamskulrungroj
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Characteristic flow of different right ventricular outflow tract morphology in repaired tetralogy of fallot patients studied by 4D-flow cardiac magnetic resonance images

A retrospective study of 120 repaired tetralogy-of-Fallot patients found similar conventional CMR, pulmonary regurgitation, and clinical outcomes across tubular and pyramidal RVOT shapes, while 4D-flow CMR detected local differences in velocity, wall shear stress, and energy loss. This shows imaging sensitivity, not yet prognostic or transcatheter-valve selection utility.

Thai researchersAuttapol Srivichean · Paweena Chungsomprasong · Yonthakan Sanwong · Thanyarat Phoprom · Chodchanok Vijarnsorn · Karnkawin Patharateeranart · Watcharachai Kangvanskol · Prakul Chanthong · Thita Pacharapakornpong · Ploy Thammasate · Kritvikrom Durongpisitkul · Jarupim Soongswang
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Eight-week high-intensity inspiratory muscle training improves cardiac autonomic function in COPD: a randomized controlled trial

A randomized trial in 39 stable COPD patients found that eight weeks of 30 inspiratory breaths twice daily at the highest tolerable intensity shifted heart-rate variability toward greater parasympathetic activity and improved six-minute walk distance and health scores versus control. The trial was small, lacked sham training, and did not measure long-term cardiac events or exacerbations.

Thai researchersPairoj Suraprapapich · Wattana B. Watanapa · Sauwaluk Dacha · Wilawan Ketpan · Somruthai Yeunyong · Kanokwan Rattanasaengloet · Nontanat Sathaporn · Benjamas Chuaychoo
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Prevalence and prognostic impact of unrecognized myocardial infarction detected by cardiac magnetic resonance in Thai patients with obesity

Among 1,053 Thai patients with BMI at least 25 kg/m2 who underwent cardiac magnetic resonance, 9.9% had scars consistent with previously unrecognized myocardial infarction. This group had more major cardiovascular events over a median 9.2 years, but most participants were selected for CMR because coronary disease was suspected, so this is not population prevalence among people with obesity.

Thai researchersPunyanuch Chayanopparat · Piyachai Siriphiphatcharoen · Issarayus Laohabut · Thanawat Ruengchaisiwawaith · Yodying Kaolawanich
Basic Science74IMPACT SIGNAL
Evidence of global relevance

Aggregatibacter actinomycetemcomitans NadN Contributes to Neutrophil Extracellular Trap Degradation

Cell-based experiments found that Aggregatibacter actinomycetemcomitans, a bacterium associated with periodontitis, can degrade neutrophil extracellular traps after capture and identified membrane-associated NadN as an important mediator. Expressing NadN in Lactococcus lactis conferred NET-degrading activity, but patient or animal evidence of disease impact is not yet available.

Thai researchersYaowapa Puanglai · Anongnard Kasorn · Oranart Matangkasombut · Dujduan Waraho‐Zhmayev · Soraya Chaturongakul · Fabien Loison
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Measurement of Plasma Free Hemoglobin Using the Hemolysis Index of the Mindray BS-800

A Siriraj team validated the Mindray BS-800 hemolysis index for plasma free hemoglobin against the Harboe method, reporting high precision and correlation across the evaluated range and a 2 mg/dL detection limit. High bilirubin caused up to 15% negative bias, and analytical validation does not establish clinical-outcome benefit.

Thai researchersPunchisa Viruttanachai · Nuttiruetai Chanpo · Anchalee Thedsawad · Janejira Kittivorapart · Theera Ruchutrakool · Chattree Hantaweepant
Public Health74IMPACT SIGNAL
Evidence of global relevance

Phylogenomic structure and resistance profiles of clinical Proteus mirabilis from a Thai hospital

Whole-genome analysis of 17 clinical Proteus mirabilis isolates from hospitals in Narathiwat found genetic diversity and multiple resistance genes despite broad phenotypic susceptibility. qnrD1 appeared on similar Col3M-associated contigs in two isolates, suggesting possible mobile elements, but the small study did not demonstrate transmission.

Thai researchersThunchanok Yaikhan · Panupong Sukpan · Jarunee Pakhawan · Sarunyou Chusri · Thitaporn Dechathai · Sirikan Suwannasin · Kamonnut Singkhamanan · Komwit Surachat
Public Health74IMPACT SIGNAL
Evidence of global relevance

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability

Electronic records covering 4,094,111 US pregnancies showed severe pregnancy-associated acute kidney injury rising from 9.0 to 27.6 per 10,000 pregnancies between 2012-2013 and the COVID-19 era. Pre-existing cardiometabolic vulnerability was associated with risk, but observational data cannot separate infection, access, testing, and secular trends.

Thai researchersNattachai Srisawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Integrative hematological and transcriptomic analysis reveals monocyte alterations and molecular signatures of inflammatory-coagulation crosstalk in long COVID

A comparison of 21 people with long COVID and 24 asymptomatic controls found lower white-cell, monocyte, and platelet counts and longer APTT. Integrated with a separate public transcriptomic dataset, the findings support a proposed inflammation-coagulation model, but the small and non-identical datasets cannot establish mechanism.

Thai researchersParin Kamseng · Namngern Chantaramanee · Rittikorn Sompan · Sarayot Rareongjai
Public Health74IMPACT SIGNAL
Evidence of global relevance

Toxicological Assessment of Oligofructans Derived from Raw Sugar Fermentation by Bacillus subtilis TISTR 001 and Their Modulatory Effects on Rat Gut Microbiota

Thai researchers evaluated oligofructans produced from raw sugar using Bacillus subtilis TISTR 001. Rats showed no treatment-related mortality or toxicity at doses up to 2,000 mg/kg/day for 90 days, alongside reported shifts in gut microbial taxa. These are preclinical animal findings and do not establish human safety or benefit.

Thai researchersSirinya Taya · Boontiwa Ninchan · Sonthaya Umsumarng · Jutamat Klinsoda · Rawiwan Wongpoomchai · Charatda Punvittayagul
Environment and Engineering74IMPACT SIGNAL
Evidence of global relevance

A Multi-Frequency SAR Framework for Methane Emission Estimation in Thai Rice Paddies

A GISTDA-led framework combines Sentinel-1 and ALOS-2 radar with IPCC accounting to detect crop timing, classify water regimes, and estimate methane from irrigated rice in Thailand's central plain. Mean absolute error was 18.5 kg CH4/ha, but structural uncertainty in the IPCC Tier 1 emission factor exceeded all algorithmic errors combined.

Thai researchersNuntikorn Kitratporn · Kanjana Koedkurang · Panu Nueangjamnong · Kittiphop Simachokchai · Chompunut Chayawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Predictors of Early Recurrence and Survival Outcomes Following Curative Resection for Colorectal Liver Metastases and the Role of Salvage Surgery: A Retrospective Cohort Study

In a retrospective cohort of 109 patients undergoing liver resection for colorectal liver metastases, high tumor burden, major intraoperative blood loss, T3/T4 primary disease, and RAS mutation were associated with early recurrence. Selected patients undergoing salvage re-hepatectomy had favorable long-term survival, but small subgroups and strong selection bias prevent causal conclusions.

Thai researchersPipit Burasakarn · Nisanat Thongkua · Vachiraluck Chalokool · Anuparp Thienhiran · Sermsak Hongjinda · Pusit Fuengfoo
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
74IMPACT SIGNAL
Clinical Medicine

Tooth surface loss associated with unshelled sunflower seed consumption: a scoping review

Frontiers in Oral Health

Thailand-affiliated authors
Thantrira Porntaveetus
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

An Optimized Protocol for the Differentiation and Fibrosis-Associated Transcriptional Priming of THP-1 Macrophages

Methods and Protocols

Thailand-affiliated authors
Janya Khattiya · Chareeporn Akekawatchai
Institutions
Thammasat University
74IMPACT SIGNAL
Global Public Health

Unraveling Hepatic Osmoregulation in Teleost: Metabolic Reprogramming and Signal Transduction in Salinity Adaptation

Reviews in Aquaculture

Thailand-affiliated authors
Sukree Hajısamae · Ilham Zulfahmi
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

Etiology and clinical severity of community-acquired acute gastroenteritis in adults at a coastal provincial hospital in Thailand

Scientific Reports

Thailand-affiliated authors
Nant The Su Mon · Sirirat Phuttasiriwat · Saranath Lawpoolsri · Kittiyod Poovorawan · Sant Muangnoicharoen · Hisham A. Imad · Prakaykaew Charunwatthana · Chatporn Kittitrakul
Institutions
Mahidol University · Samut Sakhon Hospital · Mahidol Oxford Tropical Medicine Research Unit
74IMPACT SIGNAL
Clinical Medicine

In vitro and in silico antiviral activity of Polyscias scutellaria leaf extract against drug-susceptible and drug-resistant herpes simplex virus and human papillomavirus-positive cervical cancer: implications for topical formulation development

Virus Research

Thailand-affiliated authors
Rapeepat Tipayawong · Wiratchanee Kansandee · Chaleampol Loymunkong · Padtaya Sirinantananon · Sirirat Mahawan · Kans Suwanmali · Nattarpart Lookluck · Chamsai Pientong · Tipaya Ekalaksananan · Jureeporn Chuerduangphui
Institutions
Kasetsart University · Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

Repurposing Thiazole/Benzothiazole-Based Thiazolidinone Derivatives as SARS-CoV-2 Main Protease (Mpro) Inhibitors: An Integrated Computational and Experimental Study

BioChem

Thailand-affiliated authors
Hathaichanok Chuntakaruk · Thanyada Rungrotmongkol
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Proteomics-guided characterization of Hericium erinaceus protein-capped silver nanoparticles for cytotoxicity against cancer cells and improved hemocompatibility

OpenNano

Thailand-affiliated authors
Siripong Sukdee · Onmanee Prajuabjinda · Panita Chutimanukul · Preuk Chutimanukul
Institutions
Thammasat University
74IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a multiplex PCR for simultaneous detection of Mycobacterium tuberculosis complex, Mycobacterium avium complex, and Burkholderia pseudomallei in clinical specimens

PLoS neglected tropical diseases

Thailand-affiliated authors
Hasyanee Binmaeil · Thanakon Bunsong · Janjira Thaipadungpanit · Soawarat Deekae · Sunee Chayangsu · Wang Nguitragool · Narisara Chantratita
Institutions
Mahidol University · Surin Hospital
74IMPACT SIGNAL
Clinical Medicine

Risk Factors and Outcomes of Postoperative Pulmonary Embolism in Southeast-Asian Patients Undergoing Major Surgery: A Nested Case-Control Study

Journal of Surgical Research

Thailand-affiliated authors
Nittaya Boonsri · Patteera Apiwatanakul · Sirawit Sayananon · Nichawan Koompong · Thanyawit Ninlaphut
Institutions
Mahidol University · Ramathibodi Hospital
74IMPACT SIGNAL
Clinical Medicine

Acute pharmacologic treatment versus observation for severe asymptomatic hypertension in emergency and acute care settings: a systematic review of short-term outcomes

BMC Emergency Medicine

Thailand-affiliated authors
Thanat Tangpaisarn · Wachira Wongtanasarasin · Kasidit Na Thalang · Praew Kotruchin
Institutions
Khon Kaen University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Discriminative ability and exploratory cutoff of six-minute walk distance for recent self-reported fall history in community-dwelling older adults with type 2 diabetes

BMC Geriatrics

Thailand-affiliated authors
Chiraphat Kloypan · Boonsita Suwannakul · Chakkraphan Hongluek · Tichanon Promsrisuk · Arunrat Srithawong
Institutions
University of Phayao
74IMPACT SIGNAL
Environmental Engineering

Factors affecting the release of microfibers and microplastics from laundry activities: type, quantity, and properties

Journal of Hazardous Materials Advances

Thailand-affiliated authors
Kanitchanok Muangkaew · Tunlawit Satapanajaru · Kanthika Nonthamit · Adisorn Songkun · Phonchai Noomvong · Supawit Rungmueanfa · Maneekarn Yoo-iam · Piyarat Vijuksungsith
Institutions
Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Ogataea Yeast Platform for Recombinant Porcine Interferon-Alpha 1 Production: Toward Alternative Biotherapeutics for Swine Health Management

Microorganisms

Thailand-affiliated authors
Benjamas Liwnaree · Thorntun Deangphare · Chinnawat Assana · Kitisak Sansatchanon · Jedsadakorn Ninrat · Jaraspim Narkpuk · Nanchaya Wanasen · Aekkachai Puseenam · Niran Roongsawang · Kanokarn Kocharin · Peera Jaru-Ampornpan
Institutions
National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
74IMPACT SIGNAL
Clinical Medicine

BIA-estimated visceral fat level and selected regional body composition measures are associated with high-sensitivity C-reactive protein in Thai adults

Scientific Reports

Thailand-affiliated authors
Surachat Buddhisa · Surada Satthakarn · Nattaphol Prakobkaew · Tadsawiya Padkao · Orachorn Boonla · Piyapong Prasertsri
Institutions
Burapha University
74IMPACT SIGNAL
Clinical Medicine

Virtual Phase-Contrast Microscopy for Urinary Sediment Analysis: Deep-Learning-Based Image Translation from Brightfield Microscopy

Applied Sciences

Thailand-affiliated authors
Ruchirat Rotbun · Tipparat Penglong · Atthaphong Phongphithakchai · Chonikarn Nuhom · Peempol Chokchaipermpoonphol
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

Association between early systolic blood pressure and clinical outcomes in non-critically ill patients with sepsis-associated acute kidney injury: a retrospective cohort study

Annals of Medicine

Thailand-affiliated authors
Teerawat Sriwalosakul · Surachet Vongsanim · Karn Pongsuwan · Prit Kusirisin · Surapon Nochaiwong · Chidchanok Ruengorn · Kajohnsak Noppakun
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Parkinson’s disease assessment with selfie video via feature engineering and explainable AI

PLoS ONE

Thailand-affiliated authors
Sitthatka Jaratsaeng · Anchalee Techasen · Narongrit Kasemsap · Thanapong Intharah
Institutions
Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

The Effect of Fine (PM2.5) and Coarse (PM10-2.5) Particulate Matter on Survival Outcomes in Nasopharyngeal Carcinoma Patients: A Retrospective Cohort Study in a Northern Thailand Tertiary Care Center

Journal of Clinical Medicine

Thailand-affiliated authors
Weerachai Watcharatsiriyuth · Phakhinee Leesirisopha · Pichit Sittitrai · Hanpon Klibngern · Tapanut Ariyanon · Orapan Sangiamporn · Donyarat Ruenmarkkaew
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

[2026-09-22] Efficacy and Safety of PCSK9 Inhibitors in Patients With Atherosclerotic Cardiovascular Disease at a Tertiary Hospital in the Northeast of Thailand

Research Medical Journal

Thailand-affiliated authors
Pattaraphon Tangsucharit · Chaiyasith Wongvipaporn · Naowakun Ariyapim · Chitsanupong Sumlee
Institutions
Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

Preliminary Clinical Evaluation of Inhalation Aromatherapy with Blended Essential Oils on Sleep Quality in Adults with Sleep Disturbance

Journal of Health Research

Thailand-affiliated authors
Punyanut Amorndoljai · Laddawan Choothong · Surachai Techaoei · Em–on Chaiprateep
Institutions
Rajamangala University of Technology
74IMPACT SIGNAL
Clinical Medicine

A Registry-Informed Framework for Earlier Detection of Esophageal Adenocarcinoma in Thailand: Evidence from a 16-Year Cohort Study

Methods and Protocols

Thailand-affiliated authors
Thanawat Suwatthanarak · Kullanist Thanormjit · Onchira Acharayothin · Patcharipa Chanaturakarnnon · Sripatch Sri-arporn · Tippawan Gerdsuriwong · Kanokporn Thamapala · Thapanee Saejeng · Arthit Chauykrajang · Wipanee Meesil · Tharathorn Suwatthanarak · Somsri Laiteerapong · Thammawat Parakonthun · Jirawat Swangsri · Asada Methasate · Vitoon Chinswangwatanakul · Pariyada Tanjak
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Multidisciplinary

Intercellular space limitation and ripening-associated sugar changes are associated with watercore susceptibility in durian fruit

Postharvest Biology and Technology

Thailand-affiliated authors
Naphassorn Sungtin · Kamonwan Sangsoy · Jingtair Siriphanich · Tee Havananda · Kietsuda Luengwilai
Institutions
Kasetsart University · Ministry of Higher Education, Science, Research and Innovation
74IMPACT SIGNAL
Clinical Medicine

Novel endoscopic treatment to prevent refractory caustic esophageal strictures: a propensity score-matched analysis

Surgical Endoscopy

Thailand-affiliated authors
Thitiporn Chobarporn · Dudsadee Mesiri · Papawee Chennavasin · Chadin Tharavej
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital
74IMPACT SIGNAL
Multidisciplinary

Preparation and Production of Bio‐Epoxy Composites From Sisal Fibers as a Sustainable Material for Lightweight Applications

Macromolecular Symposia

Thailand-affiliated authors
Timothy K. Mulenga · Resego Phiri · Sanjay Mavinkere Rangappa · Suchart Siengchin
Institutions
King Mongkut's University of Technology North Bangkok
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link