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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Restoring Culturally Essential Floor-Sitting in Transfemoral Prosthesis Users: A Six-Week Pilot Randomized Within-Subject Trial

A pilot randomised within-subject trial in 14 unilateral transfemoral prosthesis users compared a low-profile, femoral-adducted Asian Transfemoral Socket with each participant's usual socket after six weeks of ATS use. Twelve participants attained cross-legged sitting and six additional participants attained side-sitting with ATS, alongside comfort and quality-of-life signals. Six-minute walking distance, four-square-step balance and daily steps did not differ significantly; the small sample could not exclude clinically important harm.

Thai researchersNatthawan Sutthison · Nang Myat Myat Moe · Yasmin Nutchamlong · Marisa Amattayakul · Mathurin Rairat · Woratee Dacharux · Kazuhiko Sasaki
Clinical Medicine89IMPACT SIGNAL
Global potential

Effects of a Home-Based Fall Prevention Program in Older Lower Limb Prosthesis Users: A Randomized Controlled Trial

A randomised controlled trial assigned 44 older lower-limb prosthesis users to usual care or education plus 16 home exercises three times weekly for eight weeks; 41 completed follow-up. Change in Timed Up and Go did not differ between groups, nor did static balance or balance confidence. No falls were reported during the study, but the sample and follow-up were too small to establish fall prevention or definitive lack of benefit. The null finding applies to this relatively high-mobility study population.

Thai researchersPrawina Sakulkosol · Pieter U Dijkstra · Kazuhiko Sasaki · Jutamanee Poonsiri
Genomic Public Health and Thalassaemia88IMPACT SIGNAL
Regional policy evidence synthesis

Thalassaemia prevention in Asia: progress, challenges, and future directions

This Series paper reviews thalassaemia prevention across 14 Asian countries with high carrier frequencies, heterogeneous mutations, and unequal health-system capacity. Singapore, Malaysia, the Maldives, and Thailand had the most structured approaches, combining public awareness, carrier screening, genetic counselling, and prenatal diagnosis. Measurable success was clearest in Singapore and to a more limited extent Thailand. Many countries still face fragmented services, weak national coordination, workforce shortages, insufficient epidemiological data, and financial, technological, cultural, and social barriers. This is a regional health-system synthesis, not a comparative policy trial.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Vaccination Behaviour and Public Health89IMPACT SIGNAL
Observational cross-sectional evidence

Hepatitis B Vaccination Intention and Influencing Factors among College Students in Huanggang, Hubei, China: A Protection Motivation Theory-Based Cross-Sectional Study

This Protection Motivation Theory cross-sectional study surveyed 1,130 students aged 18–26 at three universities in Huanggang, Hubei, China, during April–May 2025. The authors dichotomized a 1–10 intention item into low scores of 1–6 and high scores of 7–10; 58.9% were in the high-intention group. In adjusted analysis, hepatitis B knowledge, vaccine knowledge, preventive behaviour, perceived severity, self-efficacy, and response efficacy were associated with higher odds of high intention, while perceived response cost was associated with lower odds. The findings identify intervention targets but do not show that changing them raises actual vaccination uptake.

Thai researchersCong Zhang · Phatcha Hirunwatthanakul · Nachalida Yukalang
Thalassaemia Epidemiology and Public Health Systems88IMPACT SIGNAL
Regional epidemiological synthesis

The Epidemiology of Thalassaemia Syndromes in Southeast Asia

This Series paper synthesizes thalassaemia epidemiology across 10 countries in WHO's South-East Asia Region by combining local expertise with a rapid literature review. Alpha- and beta-globin disorders and haemoglobin E are frequent and produce phenotypes ranging from asymptomatic carriage to lifelong transfusion dependence. Although a small set of mutations often dominates within each country, the regional spectrum is complex and population data remain incomplete. The paper highlights blood shortages, consanguinity in some settings, gender inequities, migration, and low awareness, and recommends national registries, premarital or prenatal screening, coordinated blood systems, and culturally sensitive education.

Thai researchersSuthat Fucharoen · Kittiphong Paiboonsukwong
Sustainable Livestock and Agriculture89IMPACT SIGNAL
Animal-trial evidence with modeled environmental outcomes

Crude-Glycerin Leucaena Pellets Improve Goat Feed Efficiency, but Methane Reduction Is Modeled

Thai researchers tested Leucaena leucocephala pellets containing 0–15% crude glycerin in 32 male Boer × Thai native goats for 90 days. Intake fell slightly, but gain-to-feed ratio, fermentation indicators, and modeled economics improved. Methane and greenhouse-gas reductions were estimated from a stoichiometric model rather than direct emissions measurements.

Thai researchersNirandorn Nakdaeng · Sirirat Buaphan · Kanok Chaovapasee
Electric Mobility and Energy Infrastructure85IMPACT SIGNAL
Techno-economic case-study scenario analysis

Techno-Economic Assessment of EV Charging Infrastructure in Residential Buildings in Nonthaburi, Thailand

This Nonthaburi residential-building case study compared two 60-kW DC chargers, one 60-kW DC plus two 22-kW AC chargers, and four 22-kW AC chargers. Assumptions included a seven-year project, 5.5% discount rate, mean selling price of THB7.25/kWh, service time of 4, 6, or 8 hours per day, and electricity costs of THB4.50, 4.73, or 4.95/kWh, giving 27 scenarios. All three portfolios were financially feasible under the specified conditions. Two DC chargers gave the strongest return at eight hours per day and THB4.50/kWh, while four AC chargers better fit long parking durations and lower capital and maintenance costs.

Thai researchersChatchaphon Ketviriyakit · Pasura Aungkulanon · Lakkana Ruekkasaem
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
74IMPACT SIGNAL
Clinical Medicine

Tooth surface loss associated with unshelled sunflower seed consumption: a scoping review

Frontiers in Oral Health

Thailand-affiliated authors
Thantrira Porntaveetus
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

An Optimized Protocol for the Differentiation and Fibrosis-Associated Transcriptional Priming of THP-1 Macrophages

Methods and Protocols

Thailand-affiliated authors
Janya Khattiya · Chareeporn Akekawatchai
Institutions
Thammasat University
74IMPACT SIGNAL
Global Public Health

Unraveling Hepatic Osmoregulation in Teleost: Metabolic Reprogramming and Signal Transduction in Salinity Adaptation

Reviews in Aquaculture

Thailand-affiliated authors
Sukree Hajısamae · Ilham Zulfahmi
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

Etiology and clinical severity of community-acquired acute gastroenteritis in adults at a coastal provincial hospital in Thailand

Scientific Reports

Thailand-affiliated authors
Nant The Su Mon · Sirirat Phuttasiriwat · Saranath Lawpoolsri · Kittiyod Poovorawan · Sant Muangnoicharoen · Hisham A. Imad · Prakaykaew Charunwatthana · Chatporn Kittitrakul
Institutions
Mahidol University · Samut Sakhon Hospital · Mahidol Oxford Tropical Medicine Research Unit
74IMPACT SIGNAL
Clinical Medicine

In vitro and in silico antiviral activity of Polyscias scutellaria leaf extract against drug-susceptible and drug-resistant herpes simplex virus and human papillomavirus-positive cervical cancer: implications for topical formulation development

Virus Research

Thailand-affiliated authors
Rapeepat Tipayawong · Wiratchanee Kansandee · Chaleampol Loymunkong · Padtaya Sirinantananon · Sirirat Mahawan · Kans Suwanmali · Nattarpart Lookluck · Chamsai Pientong · Tipaya Ekalaksananan · Jureeporn Chuerduangphui
Institutions
Kasetsart University · Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

Repurposing Thiazole/Benzothiazole-Based Thiazolidinone Derivatives as SARS-CoV-2 Main Protease (Mpro) Inhibitors: An Integrated Computational and Experimental Study

BioChem

Thailand-affiliated authors
Hathaichanok Chuntakaruk · Thanyada Rungrotmongkol
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Proteomics-guided characterization of Hericium erinaceus protein-capped silver nanoparticles for cytotoxicity against cancer cells and improved hemocompatibility

OpenNano

Thailand-affiliated authors
Siripong Sukdee · Onmanee Prajuabjinda · Panita Chutimanukul · Preuk Chutimanukul
Institutions
Thammasat University
74IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a multiplex PCR for simultaneous detection of Mycobacterium tuberculosis complex, Mycobacterium avium complex, and Burkholderia pseudomallei in clinical specimens

PLoS neglected tropical diseases

Thailand-affiliated authors
Hasyanee Binmaeil · Thanakon Bunsong · Janjira Thaipadungpanit · Soawarat Deekae · Sunee Chayangsu · Wang Nguitragool · Narisara Chantratita
Institutions
Mahidol University · Surin Hospital
74IMPACT SIGNAL
Clinical Medicine

Risk Factors and Outcomes of Postoperative Pulmonary Embolism in Southeast-Asian Patients Undergoing Major Surgery: A Nested Case-Control Study

Journal of Surgical Research

Thailand-affiliated authors
Nittaya Boonsri · Patteera Apiwatanakul · Sirawit Sayananon · Nichawan Koompong · Thanyawit Ninlaphut
Institutions
Mahidol University · Ramathibodi Hospital
74IMPACT SIGNAL
Clinical Medicine

Acute pharmacologic treatment versus observation for severe asymptomatic hypertension in emergency and acute care settings: a systematic review of short-term outcomes

BMC Emergency Medicine

Thailand-affiliated authors
Thanat Tangpaisarn · Wachira Wongtanasarasin · Kasidit Na Thalang · Praew Kotruchin
Institutions
Khon Kaen University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Discriminative ability and exploratory cutoff of six-minute walk distance for recent self-reported fall history in community-dwelling older adults with type 2 diabetes

BMC Geriatrics

Thailand-affiliated authors
Chiraphat Kloypan · Boonsita Suwannakul · Chakkraphan Hongluek · Tichanon Promsrisuk · Arunrat Srithawong
Institutions
University of Phayao
74IMPACT SIGNAL
Environmental Engineering

Factors affecting the release of microfibers and microplastics from laundry activities: type, quantity, and properties

Journal of Hazardous Materials Advances

Thailand-affiliated authors
Kanitchanok Muangkaew · Tunlawit Satapanajaru · Kanthika Nonthamit · Adisorn Songkun · Phonchai Noomvong · Supawit Rungmueanfa · Maneekarn Yoo-iam · Piyarat Vijuksungsith
Institutions
Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Ogataea Yeast Platform for Recombinant Porcine Interferon-Alpha 1 Production: Toward Alternative Biotherapeutics for Swine Health Management

Microorganisms

Thailand-affiliated authors
Benjamas Liwnaree · Thorntun Deangphare · Chinnawat Assana · Kitisak Sansatchanon · Jedsadakorn Ninrat · Jaraspim Narkpuk · Nanchaya Wanasen · Aekkachai Puseenam · Niran Roongsawang · Kanokarn Kocharin · Peera Jaru-Ampornpan
Institutions
National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
74IMPACT SIGNAL
Clinical Medicine

BIA-estimated visceral fat level and selected regional body composition measures are associated with high-sensitivity C-reactive protein in Thai adults

Scientific Reports

Thailand-affiliated authors
Surachat Buddhisa · Surada Satthakarn · Nattaphol Prakobkaew · Tadsawiya Padkao · Orachorn Boonla · Piyapong Prasertsri
Institutions
Burapha University
74IMPACT SIGNAL
Clinical Medicine

Virtual Phase-Contrast Microscopy for Urinary Sediment Analysis: Deep-Learning-Based Image Translation from Brightfield Microscopy

Applied Sciences

Thailand-affiliated authors
Ruchirat Rotbun · Tipparat Penglong · Atthaphong Phongphithakchai · Chonikarn Nuhom · Peempol Chokchaipermpoonphol
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

Association between early systolic blood pressure and clinical outcomes in non-critically ill patients with sepsis-associated acute kidney injury: a retrospective cohort study

Annals of Medicine

Thailand-affiliated authors
Teerawat Sriwalosakul · Surachet Vongsanim · Karn Pongsuwan · Prit Kusirisin · Surapon Nochaiwong · Chidchanok Ruengorn · Kajohnsak Noppakun
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Parkinson’s disease assessment with selfie video via feature engineering and explainable AI

PLoS ONE

Thailand-affiliated authors
Sitthatka Jaratsaeng · Anchalee Techasen · Narongrit Kasemsap · Thanapong Intharah
Institutions
Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

The Effect of Fine (PM2.5) and Coarse (PM10-2.5) Particulate Matter on Survival Outcomes in Nasopharyngeal Carcinoma Patients: A Retrospective Cohort Study in a Northern Thailand Tertiary Care Center

Journal of Clinical Medicine

Thailand-affiliated authors
Weerachai Watcharatsiriyuth · Phakhinee Leesirisopha · Pichit Sittitrai · Hanpon Klibngern · Tapanut Ariyanon · Orapan Sangiamporn · Donyarat Ruenmarkkaew
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

[2026-09-22] Efficacy and Safety of PCSK9 Inhibitors in Patients With Atherosclerotic Cardiovascular Disease at a Tertiary Hospital in the Northeast of Thailand

Research Medical Journal

Thailand-affiliated authors
Pattaraphon Tangsucharit · Chaiyasith Wongvipaporn · Naowakun Ariyapim · Chitsanupong Sumlee
Institutions
Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

Preliminary Clinical Evaluation of Inhalation Aromatherapy with Blended Essential Oils on Sleep Quality in Adults with Sleep Disturbance

Journal of Health Research

Thailand-affiliated authors
Punyanut Amorndoljai · Laddawan Choothong · Surachai Techaoei · Em–on Chaiprateep
Institutions
Rajamangala University of Technology
74IMPACT SIGNAL
Clinical Medicine

A Registry-Informed Framework for Earlier Detection of Esophageal Adenocarcinoma in Thailand: Evidence from a 16-Year Cohort Study

Methods and Protocols

Thailand-affiliated authors
Thanawat Suwatthanarak · Kullanist Thanormjit · Onchira Acharayothin · Patcharipa Chanaturakarnnon · Sripatch Sri-arporn · Tippawan Gerdsuriwong · Kanokporn Thamapala · Thapanee Saejeng · Arthit Chauykrajang · Wipanee Meesil · Tharathorn Suwatthanarak · Somsri Laiteerapong · Thammawat Parakonthun · Jirawat Swangsri · Asada Methasate · Vitoon Chinswangwatanakul · Pariyada Tanjak
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Multidisciplinary

Intercellular space limitation and ripening-associated sugar changes are associated with watercore susceptibility in durian fruit

Postharvest Biology and Technology

Thailand-affiliated authors
Naphassorn Sungtin · Kamonwan Sangsoy · Jingtair Siriphanich · Tee Havananda · Kietsuda Luengwilai
Institutions
Kasetsart University · Ministry of Higher Education, Science, Research and Innovation
74IMPACT SIGNAL
Clinical Medicine

Novel endoscopic treatment to prevent refractory caustic esophageal strictures: a propensity score-matched analysis

Surgical Endoscopy

Thailand-affiliated authors
Thitiporn Chobarporn · Dudsadee Mesiri · Papawee Chennavasin · Chadin Tharavej
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital
74IMPACT SIGNAL
Multidisciplinary

Preparation and Production of Bio‐Epoxy Composites From Sisal Fibers as a Sustainable Material for Lightweight Applications

Macromolecular Symposia

Thailand-affiliated authors
Timothy K. Mulenga · Resego Phiri · Sanjay Mavinkere Rangappa · Suchart Siengchin
Institutions
King Mongkut's University of Technology North Bangkok
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link