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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
HIV Epidemiology75IMPACT SIGNAL
Global surveillance evidence

A 1.39-million-sample map of HIV-1 shows the diversity diagnostics and vaccines must keep pace with

The study assembled 1,395,222 HIV-1 subtype observations from 154 countries between 1990 and 2024 and weighted country estimates using UNAIDS numbers of people living with HIV. In 2020-24, subtype C represented 48.7% globally, followed by subtype A at 11.5% and subtype B at 10.3%. Unique and circulating recombinant forms were also substantial. Regional patterns differed sharply: subtype C dominated southern Africa and south Asia, CRF01_AE southeast Asia, and CRF07_BC increased in east Asia.

Thai researchersDwip Kitayaporn
Cosmology75IMPACT SIGNAL
Unconfirmed emerging signal

DESI DR2 hints at evolving dark energy, but the evidence remains inconclusive

The analysis combined DESI DR2 baryon acoustic oscillations with three Type Ia supernova compilations and a compressed CMB likelihood across eight dark-energy parameterizations. Several models favored the w0 > -1, wa < 0 region and crossed the phantom divide near z about 0.5. However, the preference was driven mainly by the limited LRG1-2 tracers. Mirage-model Bayes factors were only inconclusive to moderate, and no model was robustly preferred by late-time data alone.

Thai researchersG. Mustafa
Chemistry and Clean Energy74IMPACT SIGNAL
Laboratory mechanistic evidence

Oxygen-vacancy engineering at Cu-Zn interfaces advances low-temperature methanol synthesis

Cu/ZnO catalysts for low-temperature methanol synthesis from CO2-containing syngas suffer activity and stability limits. Adding Ba regulated oxygen vacancies at Cu-Zn interfaces, reaching a TOF of 21.2 × 10^-3 s^-1 and methanol space-time yield of 655.17 g kgcat^-1 h^-1. Ba increased exposed Cu0 area, dispersion and basic sites while suppressing sintering. DFT supported interfacial oxygen vacancies as primary active sites.

Thai researchersPrasert Reubroycharoen; Noritatsu Tsubaki
Aging and Data Systems74IMPACT SIGNAL
Qualitative systems evidence

Longitudinal aging data in Asia face funding, workforce and data-sharing bottlenecks

This qualitative study interviewed 33 stakeholders across 13 East and Southeast Asian countries and regions, with additional experts from India, the UK and US. Four themes emerged: structural and contextual barriers; local adaptation of design and logistics; funding and staff-retention threats; and governance, privacy and comparability constraints. Recommendations emphasize policy alignment, multidisciplinary collaboration, harmonization and intentional inclusion of vulnerable populations.

Thai researchersDararatt Anantanasuwong
Global Health79IMPACT SIGNAL
Randomized-trial evidence

Star Homes reduced malaria by 44% and also lowered diarrhea and respiratory infections in children

The trial evaluated the Star Home, a two-story design intended to be insect-proof, cleaner, cooler and smoke-free while providing water and sanitation. Households with children younger than 13 were cluster-randomized to 110 Star Homes or 513 traditional mud and thatched-roof homes. Over three years, children in Star Homes experienced 44% less malaria, 30% less diarrhea and 18% fewer acute respiratory infections; children younger than five also had better height-for-age. The findings support housing as a modifiable determinant of health rather than merely the setting in which disease occurs.

Thai researchersMallika Imwong and Mahidol Oxford Tropical Medicine Research Unit-affiliated coauthors
Cancer Treatment77IMPACT SIGNAL
Phase 3 survival evidence

Perioperative enfortumab vedotin plus pembrolizumab improved survival outcomes in bladder cancer

Patients with muscle-invasive bladder cancer who cannot receive cisplatin have had limited perioperative options. This trial randomized 344 participants to enfortumab vedotin plus pembrolizumab before and after surgery or to surgery alone. At two years, event-free survival was 74.7% versus 39.4%, and overall survival 79.7% versus 63.1%. Pathological complete response also differed markedly, but grade 3 or worse adverse events occurred in 71.3% of the combination group.

Thai researchersPongwut Danchaivijitr
Neurology77IMPACT SIGNAL
Systematic review and meta-analysis

Pure autonomic failure phenoconverted to central synucleinopathies at about 5% per year

Pure autonomic failure may precede brain disorders driven by alpha-synuclein. Across nine longitudinal studies and 900 patients followed for a mean 6.4 years, 270 patients (30%) phenoconverted: 12% to MSA, 11% to DLB and 7% to Parkinson disease. The pooled rate was 5.09 per 100 person-years. Hyposmia favored PD/DLB over MSA, while REM sleep behavior disorder and subtle motor signs were consistent predictors of phenoconversion overall.

Thai researchersSasivimol Virameteekul
Infectious Disease and Public Health76IMPACT SIGNAL
Field detection and surveillance innovation

CRISPR-BEEPs mapped melioidosis exposure and sanitation gaps in northeast Thailand

Burkholderia pseudomallei is difficult to detect environmentally with conventional culture. CRISPR-BEEPs was benchmarked against plate inspection using double-qPCR as reference. Sensitivity was 93.5% versus 19.4%, with specificity of 100% versus 98.0%. Across 15,118 km² in northeast Thailand, the assay detected the organism in 73.3% of groundwater, 32.9% of surface water and 26.2% of piped-water samples. Detection within 10 km of a household was associated with melioidosis (OR 2.74), an association missed by conventional methods.

Thai researchersSukritpong Pakdeerat, Chalita Chomkatekaew, Phumrapee Boonklang and the Thai research network
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
74IMPACT SIGNAL
Clinical Medicine

Early Childhood Caries in Preschool Children With Cleft Lip and/or Palate: A Cross-Sectional Study of Prevalence and Contributing Factors

The Cleft Palate-Craniofacial Journal

Thailand-affiliated authors
Chotika Srinaul · Pornsuda Norchai · Saran Worasakwutiphong · Ruedee Sakulratchata
Institutions
Naresuan University · Naresuan University Hospital
74IMPACT SIGNAL
Environmental Engineering

Development of Sulfonated Carbon Catalysts from Waste Sugarcane Leaves and Tops for Effective Biodiesel Production from Free Fatty Acids or Waste Cooking Oil

ACS Sustainable Resource Management

Thailand-affiliated authors
Tanaporn Supakitmongkhol · Pakin Noppawan · Yuvarat Ngernyen · Nontipa Supanchaiyamat · Andrew J. Hunt
Institutions
Khon Kaen University · Mahasarakham University
74IMPACT SIGNAL
Environmental Engineering

Study on Compressive Strength, Flexural Behavior, and Chloride Penetration of Steel Fiber Reinforced Concrete (SFRC) under Chloride Environment

The Journal of King Mongkut s University of Technology North Bangkok

Thailand-affiliated authors
Thanapol Yanweerasak · Porjan Tuttipongsawat · Burachat Kittikornjarus
Institutions
Burapha University · Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Biosafety of rabies virus and related lyssaviruses: Risks, precautions, and knowledge gaps in diagnostic and research laboratories

PLoS neglected tropical diseases

Thailand-affiliated authors
Stuart Dean Blacksell · Khanh Kim Le
Institutions
Mahidol University
74IMPACT SIGNAL
Engineering

Physicochemical and microbiological qualities of shrimp (Litopenaeus vannamei) coated with pectin incorporated with green tea spent extract during refrigerated storage

Journal of Food Composition and Analysis

Thailand-affiliated authors
Nilesh Prakash Nirmal · Arthittaya Thuanthong · Anantita Sangsuriyawong · Zain ul Abideen
Institutions
Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Efficacy of 7% Ectoine Cream for Facial Seborrheic Dermatitis: A Randomized Controlled Trial of Acute and Maintenance Phases

Cosmetics

Thailand-affiliated authors
Nirynya Jitarayameth · Nanticha Kamanamool · Chotinij Lertphanichkul · Chantalck Muennarong · Montree Udompataikul
Institutions
Srinakharinwirot University
74IMPACT SIGNAL
Clinical Medicine

Ventilator-dependent unit as a specialized weaning unit in a resource-limited setting: Evidence review, implementation framework and clinical outcome

Clinical Critical Care

Thailand-affiliated authors
Rathasart Pengpu · Atikun Limsukon · Juthamas Inchai · Tula Wongpalee · Konlawij Trongtrakul
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Trade-Offs in Growth Performance, Serum Biochemistry, and Fillet Amino Acid Profiles of Red Tilapia Fed Graded Levels of Azolla microphylla Meal in a Fishmeal Replacement Blend, with Exploratory Observations on Intestinal Microbiota

Veterinary Sciences

Thailand-affiliated authors
Panitnart Auputinan · Nantapong Sumket · Somchart Tana · Payungsuk Intawicha · Phanit Srisuttha · Phadungnaree Saenmuang · Sontaya Sookying · Dutrudi Panprommin · Paiboon Panase
Institutions
University of Phayao
74IMPACT SIGNAL
Energy and Materials

Development and Field Validation of a Solar-Powered Smart Buoy for Saltwater Intrusion Monitoring

Solar

Thailand-affiliated authors
Wirote Ritthong · Kittigorn Chalernphon · Nutthapong Kunla · Pongthep Poungthong · Naphat Albutt · Akom Boonpunya · Khongdet Phasinam
Institutions
Shinawatra University · Pathumthani University · Bangkokthonburi University · King Mongkut's Institute of Technology Ladkrabang
74IMPACT SIGNAL
Clinical Medicine

A Bioactive Microbial Extract from Priestia aryabhattai PTKU-123 Suppresses Phytophthora palmivora Disease and Reprograms Defense-Associated Metabolism in Durian Seedlings

Sci

Thailand-affiliated authors
Nattawut Chaloeykram · Chutirat Ongputhza · Phatlada Saengsurin · Punyaphat Bunroengsak · Arisara Thongpech · Nisit Watthanasakphuban · Siam Popluechai · Sumallika Morakul · Nattakorn Kuncharoen · Paiboon Tunsagool
Institutions
Kasetsart University · Mae Fah Luang University
74IMPACT SIGNAL
Clinical Medicine

Clinical outcomes of different preoperative treatment approaches in locally advanced rectal cancer: real-world experience

BMC Cancer

Thailand-affiliated authors
Jitlada Khonglim · Napat Angkathunyakul · Ananya Pongpaibul · Janjira Petsuksiri · Vutisiri Veerasarn · Woramin Riansuwan · Vitoon Chinswangwatanakul · Charuwan Akewanlop · Krittiya Korphaisarn
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Analysis of Factors Affecting Consultation-to-Puncture Time in Patients with Acute Ischemic Stroke within a Metropolitan Hospital Referral Network: A Retrospective Cohort Study

Asian Journal of Neurosurgery

Thailand-affiliated authors
Ittichai Sakarunchai · Peerawas Santheerapharp · Potchara Veerarattakul · Chabarprai Tonglor
Institutions
Bangkok Metropolitan Administration
74IMPACT SIGNAL
Clinical Medicine

Functional alterations of neutrophils from β-thalassemia patients exposed to Pythium insidiosum: An ex vivo study

PLoS ONE

Thailand-affiliated authors
Pasinee Sangsiwarit · Wisitsak Phoksawat · Nattiya Teawtrakul · Sonwit Phanabamrung · Parama Budmala · Ariya Chindamporn · Pratsanee Hiengrach
Institutions
Khon Kaen University · Srinagarind Hospital, Faculty of Medicine, Khon Kaen University · Chulalongkorn University
74IMPACT SIGNAL
Environmental Engineering

Characterization and biodegradation of polyhydroxyalkanoates (PHAs) in a simulated marine environment

Scientific Reports

Thailand-affiliated authors
Piyawan Kunriya · Pilanee Vaithanomsat · Antika Boondaeng · Wachirah Jaingam · Chanaporn Trakunjae
Institutions
Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Chemical and Proteomic Characterization of Bioactive Protein-Enriched Fraction from Schizophyllum commune with Anticancer Activity in HeLa Cells

ACS Omega

Thailand-affiliated authors
Saranya Sedtananun · Lueacha Tabtimmai · Chanapat Butsukon · Chanikan Sonklin · Kiattawee Choowongkomon
Institutions
King Mongkut's University of Technology North Bangkok · Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Mucoadhesive Chitosome-Based Buccal Delivery of Goat Placenta-Derived Bioactive Macromolecules: Effects on 5-Fluorouracil-Induced Gingival Fibroblast Injury

Pharmaceutics

Thailand-affiliated authors
Worranan Rangsimawong · Phaijit Sritananuwat · Sureewan Duangjit · Natawat Chankana · Praneet Opanasopit
Institutions
Ratchathani University · Ubon Ratchathani University · Rangsit University · Silpakorn University
74IMPACT SIGNAL
Clinical Medicine

Integrated microfluidic platform for continuous downstream purification and in-line residual ethanol monitoring of exosome-mimetic nanoparticles

Sensors and Actuators B Chemical

Thailand-affiliated authors
Vasita Lapee-e · Abdulhadee Yakoh · Hyo‐Il Jung
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Cytotoxicity, antibacterial efficacy, and fluoride content of commercial herbal toothpastes

BDJ Open

Thailand-affiliated authors
Nuttanun Poeaim · Pasiree Thongthai · Pimduean Sivavong · Phakvalunch Rujiraprasert · Thanaphum Noom Osathanon · Thawanrat Singthong · Budsaraporn Boonsuth · Dusit Nantanapiboon
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Sertoli cell tumor in a boar: Pathological and immunohistochemical comparison with canine cases

The Thai Journal of Veterinary Medicine

Thailand-affiliated authors
Anurak Tibboo · Hataitip Changchum · Nuttiya Saengrueng · Panvard Unjai · Natchanon Dumniem · Kasem Rattanapinyopituk · Komkrich Teankum
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Supercharged Colonic Interposition for Total Oesophageal Reconstruction: Technical Refinements, Perioperative Protocol, and Functional Outcomes

Siriraj Medical Journal/San Sirirat

Thailand-affiliated authors
Sarut Chaisrisawadisuk · Pornchanit Karanthakarn · Sirin Apichonbancha · Nutcha Yodrabum · Jirawat Swangsri
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Engineering

Efficacy of Fluoride Toothpaste Fortified With Micro‐ and Nano‐Hydroxyapatite on Remineralization and Surface Roughness of Synthetic Enamel

Clinical and Experimental Dental Research

Thailand-affiliated authors
Porawit Kamnoedboon · Phakvalunch Rujiraprasert · Thawanrat Singthong · Thanaphum Noom Osathanon · Chalermkwan Makornpan · Chawalid Pianmee · Naruporn Monmaturapoj · Dusit Nantanapiboon
Institutions
Chulalongkorn University · National Science and Technology Development Agency · Thailand National Metal and Materials Technology Center · Surin Hospital
74IMPACT SIGNAL
Clinical Medicine

Associations of Maximal Inspiratory Pressure With Lung Hyperinflation, Functional Capacity, and Muscle Strength in Patients With Chronic Obstructive Pulmonary Disease

Physiotherapy Research International

Thailand-affiliated authors
Jarinya Kraisalee · Warawut Chaiwong · Teelek Lungta · Nutcha Vimolsutjarit · Mujalin Prasannarong · Athavudh Deesomchok · Sauwaluk Dacha
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Longitudinal Changes in Cervical Length Prior to the Onset of Spontaneous Labor at Term Gestation

AJOG Global Reports

Thailand-affiliated authors
Puntabut Warintaksa · Supakorn Chaiyakarn · Maolee Bhuwapathanapun · Chalongraj Ratanawongsaroj · Orathai Munggaranonchai · Sasivimol Rattanasiri · Piya Chaemsaithong
Institutions
Mahidol University · Ramathibodi Hospital · Phramongkutklao Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link