Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection
Two randomized controlled phase 3 trials are investigating the antisense oligonucleotide drug bepirovirsen in patients with chronic hepatitis B. with researchers from Chiang Mai University co-authoring
This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.
Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.
This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.
Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.
This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’
Phetchabun’s micro-elimination programme linked fingerstick anti-HCV testing, HCV-RNA confirmation, and 12-week sofosbuvir/velpatasvir treatment through primary-care and district-hospital services across all 11 districts under universal health coverage. From 2020 to April 2026, 389,547 of 400,567 targeted people were screened (97.25%); 14,845 of 18,340 anti-HCV-reactive participants received RNA confirmation (80.94%), identifying 10,996 active infections. Of 8,961 treatment-eligible patients, 8,842 received therapy (98.67%); among 6,719 evaluated at SVR12, 6,474 were cured (96.35%). The programme demonstrates province-scale test-to-treat feasibility, but not yet the incidence or mortality reductions required for elimination.
This study linked national policy, hospital systems, and provider behaviour in Indonesia, Nepal, Thailand, and Viet Nam during 2022–2023. It included 486 participants across 16 hospitals. All countries had antimicrobial-stewardship policies, but financing, enforcement, training, microbiology-data use, and inter-programme coordination were uneven. Hospitals averaged 72% on G-ASET, with tracking and reporting highest at 75% and training lowest at 66%. The two Thai hospitals scored 81.3% and 80.6% overall, yet both scored only 50% for training. These results identify actionable system gaps; they do not experimentally show that any intervention reduced antibiotic use, resistance, or mortality.
The article synthesises publications and long-running surveillance at the animal–human interface in Laos and Cambodia, covering Taenia solium, Trichinella, Streptococcus suis, rickettsiae, melioidosis, hepatitis E, and Japanese encephalitis. Its recurring message is diagnostic invisibility caused by limited laboratories and fragmented human–animal–environment systems, with risks embedded in smallholder livestock, informal slaughter, raw-meat consumption, wet markets, and animal-contact occupations. It proposes scaling abattoir, animal-sentinel, market, and environmental surveillance alongside livelihood-aware risk communication. This is a narrative synthesis, not a systematic review or one national survey, so it maps patterns and gaps rather than estimating current national burden.
Thai researchersStuart D. Blacksell · Syseng Khounsy · Jarunee Siengsanan-Lamont · Lida Kong · Jaison B. Kolenchery · Paul N. Newton · Nicholas P. J. Day
Using individual surveillance records from 2019–2021, this study examined both malaria case patterns and district factors associated with elimination across Sumatra. Of 13,386 reported cases, 71.8% were Plasmodium vivax; among 11,390 investigated cases, 15.3% were classified as imported. Multilevel models identified associations with mobile populations and clinical characteristics, while district elimination was associated with higher human development, lower historical burden, and fewer endemic neighbours. These are observational surveillance associations, not causal effects of a policy.
Thai researchersKarina D Lestari · Sri B Fajariyani · Pimphen Charoen · Saranath Lawpoolsri · Wirichada Pan-ngum
This synthesis mapped malaria evidence among migrant and mobile populations in the Greater Mekong Subregion across epidemiology, access, prevention, and health-system challenges. Of 847 records, 52 studies met inclusion criteria. Reported burden was generally low but highly variable, with hidden reservoirs from asymptomatic or submicroscopic infection in border and forest settings. Structural barriers contributed to delayed diagnosis, inconsistent prevention, and reliance on informal or cross-border care. The review exposes intervention-evaluation gaps rather than proving which approach works best.
Thai researchersPyae Linn Aung · Ajjima Thussachan · Naing Bo Bo Min · Jetsumon Sattabongkot
This Joanna Briggs Institute–guided scoping review synthesised 50 studies of resilience among family caregivers across cancer types and stages of care. The evidence was organised into risk factors, protective factors, and psychosocial or functional outcomes. Measurement tools varied substantially, and few interventions designed to strengthen family resilience had been tested empirically.
Thai researchersSiyu Yang · Xian Wang · Qing Li · Hunsa Sethabouppha
Using the Dahlem Framework, this commentary distinguishes caries control, elimination, and eradication. Global eradication is judged conceptually unattainable because caries has no single agent, interruptible transmission cycle, vaccine, or universal incidence surveillance. Elimination as a stable end to caries as a public-health problem in a defined population is presented as a plausible, measurable goal.
Thai researchersHabib Benzian
BIBLIOGRAPHIC RESEARCH WATCHLIST
Bibliographic research records
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
73IMPACT SIGNAL
Clinical Medicine
Efficacy and safety of intrathecal morphine compared to peripheral nerve blocks in patients underwent foot and ankle surgery: A propensity score analysis
Srinakharinwirot University · Rajamangala University of Technology Suvarnabhumi · Maharat Nakhon Ratchasima Hospital · Nakhon Ratchasima Rajabhat University · Nakhon Sawan Rajabhat University · Thaksin University
73IMPACT SIGNAL
Environmental Engineering
Extreme rainfall trends and return periods under CMIP6 scenarios in Southern Thailand
Comparative Effects of Ethanol Concentration on Phytochemical Profiles and In Vitro Bioactivities of Lime (Citrus aurantifolia) and Lemon (Citrus limon) Peel Extracts
Journal of Food Health and Bioenvironmental Science
Chiang Mai University · Burapha University · National Center for Genetic Engineering and Biotechnology
72IMPACT SIGNAL
Multidisciplinary
Characterization of Ethyl Lauroyl Arginate‐Enhanced Poly(Vinyl Alcohol)/Chitosan Biodegradable Indicator Films Containing Betalains From White‐Fleshed Dragon Fruit Peels
IL15.3, a synthetic antimicrobial peptide, attenuates LPS-induced inflammatory responses in RAW 264.7 macrophages via transcriptional and proteomic modulation
Srinakharinwirot University · Dhurakij Pundit University · Chulabhorn Royal Academy · Chiang Mai University
72IMPACT SIGNAL
Multidisciplinary
Spatiotemporal Analysis of Land Use Change in Mueang Phuket District, Phuket Province, Thailand, Between 2021 and 2025 Using Supervised Satellite Image Classification
International Journal of Advances in Engineering and Management
Electric-field process intensification in food and materials: Pulsed electric field, radio-frequency heating and cold plasma, with pilot- and community-scale demonstrations
Journal of Electrostatics
Thailand-affiliated authors
Chatchawan Kantala · Panich Intra
Institutions
Rajamangala University of Technology Lanna
72IMPACT SIGNAL
Clinical Medicine
Single-Step Sample-Activated Alternating Sequential Flow Enables Autonomous Multistep Electrochemical Lateral Flow Detection of Mpox Virus DNA